Blažej Palkóci

Establishment of Coala: a novel 3D and 2D cancer cell line derived from colorectal cancer liver metastasis

Sandra Meršaková, Juraj Marcinek, Dušan Braný, Olga Chodelkova et autres

Metastatic colorectal cancer is one of the most critical causes of cancer-related dead in patients suffering this type of malignancy. As the liver metastases are found in almost 25-50% of all colorectal cancer patients, there is an urgent need for suitable in …

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Distal pancreatectomy

Martin Vojtko, Kristina CMARKOVA, Miroslav Pindura, Blažej Palkóci et autres

NTRODUCTION: Distal pancreatectomy is a standard surgical procedure for selected benign, premalignant, and malignant lesions localized in the pancreatic body or tail. Surgical resection remains the only curative option for patients diagnosed with adenocarcinoma of the pancreas. PATIENTS AND METHODS: Perioperative and …

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First Czech-Slovak Intercountry Islet Autotransplantation—Brief Case Report

Peter Girman, Jan Kříž, Lenka Németová, Ivan Leontovyč et autres

Islet autotransplantation is an effective procedure that prevents or lessens diabetes after a total pancreatectomy. Posttransplant insulin-independence rate may be as high as 30%, according to the recent data reported by experienced centers.1 The procedure availability in various countries depends on the …

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International autotransplantation of Langerhans islets into the portal tract after total pancreatectomy in a patient with chronic hereditary pancreatitis – case report and review of current literature

Daniel Bolek, Lenka Nosáková, Miroslav Pindura, Patrik Horan et autres

Summary: Chronic pancreatitis with repeated painful relapses is a severe multifactorial, fibroinflammatory syndrome that significantly affects the quality of life of patients, mainly in terms of pain, development of diabetes mellitus, and repeated attacks of acute pancreatitis. Autologous islet transplantation after total …

Establishment of PANDA - a new human pancreatic ductal adenocarcinoma cell line with 3D cell culture technology

Romana Záhumenská, Michal Kalman, Juraj Marcinek, Sandra Meršaková et autres

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive type of malignancy with one of the worst prognoses amongst any type of cancer.Surgery is applicable only to the limited number of patients with locally resectable tumors and currently represents the only curative treatment …

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EXPERIENCES WITH EXPANDED CRITERIA DONORS: 10-YEAR ANALYSIS OF THE MARTIN, SLOVAKIA TRANSPLANT CENTER

Ivana Dedinská, Blažej Palkóci, Juraj Miklušica, Martin Vojtko et autres

Background and Aims: Kidneys from expanded criteria donors with diagnosis of brain death have become a part of the organ transplant program, which have thus increased the number of transplants. Method: In this retrospective analysis, we identified the expanded criteria donors in …

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Experiences With Expanded Criteria Donors: 10-Year Analysis of the Martin, Slovakia Transplant Center.

Ivana Dedinská, Blažej Palkóci, Martin Vojtko, Denisa Osinová et autres

OBJECTIVES: Kidneys from expanded criteria donors with diagnosis of brain death have become a part of the organ transplant program, which have thus increased the number of transplants. MATERIALS AND METHODS: In this retrospective analysis, we identified the expanded criteria donors in …

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Donor Body Mass Index as a Risk Factor for Delayed Onset of Graft Function

Juraj Miklušica, Ivana Dedinská, Blažej Palkóci, Alexander Sendrey et autres

Delayed graft function continues to pose a significant challenge to clinicians in the context of kidney transplantation. The objective of this retrospective, 5-year analysis is to identify the parameters of beating heart donors and those of recipients that affect the delayed development …

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The role of proteinuria, paricalcitol and vitamin D in the development of post-transplant diabetes mellitus

Ivana Dedinská, Ľudovít Laca, Juraj Miklušica, Blažej Palkóci et autres

INTRODUCTION: Post-transplant diabetes mellitus (PTDM) occurs most frequently during the first year after transplantation. We focused on parameters of calcium-phosphate metabolism and proteinuria as possible new risk factors for PTDM after kidney transplantation. MATERIALS AND METHODS: We have prospectively identified risk factors …

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Results of Kidney Transplantation from Expanded Criteria Donors: A Single-Center Experience.

Blažej Palkóci, Martin Vojtko, Jana Fialová, Denisa Osinová et autres

BACKGROUND: Collection of kidneys from extended criteria donors (ECD) with diagnosed brain-death forms a part of the collection program that increases the number of transplantations. OBJECTIVE: To compare the results of ECD with those of standard criteria donors (SCD). METHODS: In a …

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Results of Kidney Transplantation from Expanded Criteria Donors: A Single-Center Experience

Blažej Palkóci, Martin Vojtko, J Fialov�, D Osinov� et autres

Background: Collection of kidneys from extended criteria donors (ECD) with diagnosed brain-death forms a part of the collection program that increases the number of transplantations. Objective: To compare the results of ECD with those of standard criteria donors (SCD). Methods: In a …

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Flow Cytometry Panel-Reactive Antibody Screening of Anti-HLA Antibodies in the Waiting List Significantly Reduces the Occurrence of Acute Rejection After Kidney Transplantation

Ivana Dedinská, N Macková, Katarína Kajová Macháleková, Juraj Miklušica et autres

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