Stephen Morris

A randomised controlled trial to assess the feasibility and acceptability of remote psychosocial and exercise interventions for people with lupus: The ADAPT feasibility trial

Thomas Pollak, David D’Cruz, Wendy Diment, Michael Bosley et autres

Limited psychosocial support is available for people with lupus despite the highly reduced quality of life. This study assessed the acceptability, feasibility, and effectiveness estimations, of three (two psychosocial, one exercise) interventions. Lupus patients (N = 124) were randomised to a control …

gb, qa, us (code pays fourni par la source)

Procurement and early deployment of artificial intelligence tools for chest diagnostics in NHS services in England: a rapid, mixed method evaluation

Angus I. G. Ramsay, Nadia Crellin, R. C. Lawrence, Holly Walton et autres

Background: Artificial Intelligence (AI) may support accurate, efficient radiology diagnostics. However, little is known about implementing AI in clinical settings. In 2023, NHS England launched a programme funding 12 networks of 66 NHS Trusts to implement AI for chest diagnostics, including lung …

gb (code pays fourni par la source)

Costs and cost-effectiveness of returning secondary findings from genomic sequencing based on the return of additional findings in the 100,000 Genomes Project

Emma J. Smith, Melissa Hill, Lyn S. Chitty, Stephen Morris

gb (code pays fourni par la source)

Artificial intelligence for diagnostics in radiology practice: a rapid systematic scoping review

R. C. Lawrence, Emma Dodsworth, Efthalia Massou, Chris Sherlaw‐Johnson et autres

Background: The aim of this review was to evaluate evidence on the use of Artificial Intelligence (AI) to support diagnostics in radiology, including implementation, experiences, perceptions, quantitative, and cost outcomes. Methods: = 6). Findings: Factors influencing AI adoption were identified, including the …

gb (code pays fourni par la source)

Evaluating the return of additional findings from the 100,000 Genomes Project: A mixed-methods study exploring participant experiences of receiving secondary findings from genomic sequencing

Bethany Stafford‐Smith, Morgan Daniel, Michelle Peter, Jana Gurasashvili et autres

PURPOSE: The 100,000 Genomes Project participants could consent to receive additional findings (AFs) for variants associated with susceptibility to cancer and familial hypercholesterolemia. Here, we evaluate stakeholder experiences to inform clinical practice. METHODS: Mixed-methods study conducted at 18 sites across England that …

gb, ca (code pays fourni par la source)

OA33 A randomised controlled trial to assess the feasibility and acceptability of remote psychosocial and exercise interventions for people with lupus: the ADAPT feasibility trial

Melanie Sloan, David D’Cruz, Thomas Pollak, Wendy Diment et autres

Abstract Background/Aims Limited support is available to help people adapt to living with lupus despite the highly reduced quality of life, and almost 50% of lupus patients having experienced suicidal thoughts. Reducing the high burden of symptoms through psychosocial and exercise interventions …

gb, ca (code pays fourni par la source)

‘I still can’t forget those words’: mixed methods study of the persisting impact on patients reporting psychosomatic and psychiatric misdiagnoses

Melanie Sloan, Michael Bosley, Caroline Gordon, Thomas Pollak et autres

OBJECTIVES: This research aimed to improve understanding of persisting impacts of patient-reported psychosomatic and psychiatric misdiagnoses on patients with systemic autoimmune rheumatic diseases (SARDs). METHODS: Mixed methods data from two SARDs cohorts were analysed (N = 1543 and N = 1853). Validated …

gb, qa (code pays fourni par la source)

Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers

Anne Miles, R. Steele, Gemma Hutton, Stephen Morris

AIM: Treatment for rectal cancer can leave patients with a permanent stoma or bowel dysfunction. In this work we aimed to examine preferences for treatment outcomes among people with and without rectal cancer. METHOD: Our discrete choice experiment examined the effect of …

gb (code pays fourni par la source)

Rapid mixed-method evaluation of implementing Artificial Intelligence in chest diagnostics for lung disease

Angus I. G. Ramsay, Chris Sherlaw‐Johnson, Kevin Herbert, Nadia Crellin et autres

gb (code pays fourni par la source)

Implementation of a National Prenatal Exome Sequencing Service in England: Cost‐Effectiveness Analysis

Emma J. Smith, Melissa Hill, Michelle Peter, Wing Han Wu et autres

OBJECTIVE: Prenatal exome sequencing (pES) for diagnosing fetal structural anomalies commenced in the English National Health Service (NHS) in 2020. We evaluated cost-effectiveness to the healthcare system, and costs to families, of pES in addition to standard testing, compared to standard testing …

gb (code pays fourni par la source)

Implementation of a national prenatal exome sequencing service in England: cost-effectiveness analysis

Emma J. Smith, Melissa Hill, Michelle Peter, Wing Han Wu et autres

Objective To evaluate costs and cost-effectiveness to the healthcare system, and costs to families, of a national prenatal exome sequencing (pES) service additional to standard testing, compared to standard testing alone. Design A cost-effectiveness analysis combining costs, outcomes, parent and professional interview …

gb (code pays fourni par la source)

State Capacity Coordination Centers to Facilitate Access to Acute Care: A National Survey and Analysis

Brian J. Franklin, Steven H. Mitchell, Lisa Villarroel, Karyn D. Baum et autres

us (code pays fourni par la source)