Profil bibliographique

Yann-Vai LeBihan

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

2Publications signalées
11Citations signalées
1Affiliations récentes

Les institutions déclarées

Institute of Cancer Research

Les domaines associés

Protein Degradation and InhibitorsCancer-related Molecular PathwaysMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research

Les publications récentes

2023 conference-abstract OpenAlex

Investigating the Functional Impact of CRBN Mutations on Response to IMiD/Celmod Agents in Myeloma

Yakinthi Chrisochoidou, Yann-Vai LeBihan, Salomon Morales, Shannon Martin et autres

Introduction Immunomodulatory drugs (IMiDs) have revolutionized the treatment of myeloma (MM), with lenalidomide (Len) and pomalidomide (Pom) approved and novel cereblon E3 ligase modulators (CELMoDs, e.g. iberdomide, Iber and mezigdomide, Mezi) in clinical trials. IMiDs and CELMoDs bind to cereblon (CRBN), which …

gb, us (code pays fourni par la source)

6 citations Blood
2021 conference-abstract OpenAlex

Abstract LBA004: Identification of GSPT1-directed molecular glue degrader (MGD) for the treatment of Myc-driven breast cancer

Gérald Gavory, Bernhard Fasching, Débora Bonenfant, Amine Sadok et autres

Abstract The Myc family of transcription factors is a well-established driver of human cancers. However, despite being amongst the most frequently mutated, translocated and overexpressed oncogenes, no therapy directly targeting the Myc family members has been developed to date. Abnormal activation of …

ch, gb (code pays fourni par la source)

5 citations Molecular Cancer Therapeutics
Notice OpenAlex

BNTIC News n’est pas le producteur de ces données. Les publications sont interrogées à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, AfricArXiv, ROR et la Banque mondiale, sans clé d’accès. OpenAlex reste optionnel. Aucun service payant n’est nécessaire et aucune donnée externe n’est enregistrée en base. Consulter les sources et leurs limites.