Winnie Muyindike

Delays in Tuberculosis Treatment Among People With Pulmonary Tuberculosis in East Africa: Findings From a Prospective Cohort Study

Kirsten Prabhudas-Strycker, Lameck Diero, Winnie Muyindike, Helen Byakwaga et autres

Background: Although timely tuberculosis (TB) diagnosis and treatment are essential to TB elimination, care delays remain a challenge. Understanding factors associated with delayed TB diagnosis and treatment may inform interventions. Methods: The TB Sentinel Research Network of the International epidemiology Databases to …

us, Kenya, Ouganda (code pays fourni par la source)

Gabapentin to achieve HIV viral load suppression in people with risky drinking in Mbarara, Uganda: study protocol for a randomized, double-blinded, placebo-controlled trial (GRAIL)

Ve Truong, Allen Kekibiina, Winnie Muyindike, Natalia Gnatienko et autres

BACKGROUND: Ending the HIV epidemic requires achieving HIV viral load (HVL) suppression for key populations including those with risky drinking. Gabapentin can decrease alcohol use and thus holds potential for improving medication adherence and HIV viral load suppression for individuals with HIV …

us, Ouganda (code pays fourni par la source)

Exploring Phosphatidylethanol Cutoffs for Self‐Reported Unhealthy Alcohol Use: An International Multi‐Site Analysis

Pamela M. Murnane, Fan Xia, Majid Afshar, Jennifer L. Brown et autres

ABSTRACT Background Unhealthy alcohol use is a preventable cause of morbidity and mortality, yet screening is hampered by inaccurate reporting. Phosphatidylethanol (PEth) is a biomarker that quantifies total drinking over the past 2–4 weeks, but PEth cutoffs for unhealthy drinking have not …

us, Afrique du Sud, gb, Tanzanie, ru, Ouganda, au (code pays fourni par la source)

High Prevalence of Unhealthy Alcohol Use Among Persons with HIV, Viral Non-suppression and Any Alcohol Use in Mbarara, Uganda: A Brief Report

Rebecca Fisk-Hoffman, Allen Kekibiina, Winnie Muyindike, Huimin Cheng et autres

Unhealthy alcohol use is associated with HIV viral non-suppression. It is unclear how common unhealthy alcohol use is among non-suppressed persons with HIV (PWH) who drink alcohol. We conducted chart reviews to recruit PWH in Uganda with recent viral non-suppression for a …

us, Ouganda, tw (code pays fourni par la source)

Novel integrase mutations linked to genotypic DTG resistance in African non-B HIV-1 strains: the DTG RESIST study

Nuri Han, Tom Loosli, Mamatha Sauermann, İpek Çelikağ et autres

BACKGROUND: Integrase mutations associated with dolutegravir resistance have been well characterized, but based on limited data from non-B subtypes. OBJECTIVES: We aim to identify potential integrase mutations not currently classified as integrase strand transfer inhibitor (INSTI) resistance mutations (DRMs) in individuals with …

ch, Afrique du Sud, Zambie, us, Ouganda, Zimbabwe, in, Malawi, Congo, Côte d’Ivoire, nl, Burkina Faso, fr, gb (code pays fourni par la source)

Novel integrase mutations linked to genotypic DTG resistance in African non-B HIV-1 strains: the DTG RESIST study.

Nuri Han, Tom Loosli, Mamatha Sauermann, İpek Çelikağ et autres

Background Integrase mutations associated with dolutegravir resistance have been well characterized, but based on limited data from non-B subtypes.Objectives We aim to identify potential integrase mutations not currently classified as integrase strand transfer inhibitor (INSTI) resistance mutations (DRMs) in individuals with viremia …

ch, nl (code pays fourni par la source)

Novel integrase mutations linked to genotypic DTG resistance in African non-B HIV-1 strains: the DTG RESIST study

Nuri Han, Tom Loosli, Mamatha Sauermann, İpek Çelikağ et autres

Background: Integrase mutations associated with dolutegravir resistance have been well characterized, but based on limited data from non-B subtypes. Objectives: We aim to identify potential integrase mutations not currently classified as integrase strand transfer inhibitor (INSTI) resistance mutations (DRMs) in individuals with …

Vitamin D deficiency and its associated factors among HIV patients at Mbarara City Health Centre IV, south-western Uganda

Jazira Tumusiime, Charles Nkubi Bagenda, Daniel Nzaramba, Bashir Ruzige et autres

Background: HIV is a global health challenge. Despite increased life expectancy because of antiretroviral therapy, vitamin D deficiency (VDD) remains widespread among HIV-positive individuals. Factors such as poor nutrition, limited sunlight exposure, and certain medications, contribute to high VDD rates. Despite this, …

Ouganda, us (code pays fourni par la source)

‘Empowerment’ as a proximal implementation outcome for task shifting with informal cadres: findings from a qualitative study with traditional healers in rural Uganda

Misha Hooda, Gabriel Nuwagaba, Sylvia Natukunda, William Bugeza et autres

BACKGROUND: Task shifting and task sharing (TSS) are widely used implementation strategies to expand HIV service delivery in low-resource settings. Informal lay health workers, such as traditional healers (THs), have been proposed as critical partners in bridging service delivery gaps. However, the …

us, Ouganda (code pays fourni par la source)

Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning

Cristina Espinosa da Silva, Robin Fatch, Winnie Muyindike, Nneka Emenyonu et autres

BACKGROUND: Unhealthy alcohol use is prevalent among persons with HIV (PWH) and is associated with adverse outcomes, but is underestimated partly due to use of self-reported measures prone to underreporting. Phosphatidylethanol (PEth) is a direct measure of past month alcohol consumption but …

us, Ouganda (code pays fourni par la source)

Novel integrase mutations linked to genotypic DTG resistance in non-B HIV-1 strains from African participants: The DTG RESIST study

Nuri Han, Tom Loosli, Mamatha Sauermann, İpek Çelikağ et autres

Background: Integrase mutations associated with dolutegravir resistance have been well characterized, but based on limited data from non-B subtypes. Objectives: We aim to identify integrase mutations not currently classified as integrase strand transfer inhibitor (INSTI) resistance mutations (DRMs) in individuals with viremia …

ch, Afrique du Sud, Zambie, us, Ouganda, in, Malawi, Congo, Côte d’Ivoire, Burkina Faso, Rwanda, gb (code pays fourni par la source)

A mobile health-based alcohol reduction intervention and its usability among persons with Human Immunodeficiency Virus in Uganda

Julian Adong, Robin Fatch, Naomi Sanyu, Anita Katusiime et autres

Background: Human Immunodeficiency Virus (HIV) and alcohol use are widespread in sub-Saharan Africa (sSA), negatively impacting the continuum of HIV care, from prevention and testing to treatment outcomes. Reducing alcohol consumption among people with HIV (PWH) is therefore a public health priority. …

Ouganda, us (code pays fourni par la source)