Tamíris Amanda Júlio

Factors associated with non-pathogenic antibodies against desmoglein-3 in pemphigus foliaceus

Sebastián Vernal, Tamíris Amanda Júlio, Fernando Henrique Alves, Aline Turatti et autres

BACKGROUND: Anti-desmoglein (Dsg)1 is produced in pemphigus foliaceus (PF), affecting exclusively the skin. Pemphigus vulgaris (PV) shows the production of anti-Dsg3 in the mucosal form, and anti-Dsg1 and 3 in the mucocutaneous form. Anti-Dsg3 autoantibodies have been rarely reported in PF. OBJECTIVES: …

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Bullous pemphigoid and milia: prevalence and clinical laboratory findings in a Brazilian sample

Sebastián Vernal, Ederson Valei Lopes de Oliveira, Roberto Bueno Filho, Tamíris Amanda Júlio et autres

BACKGROUND: Bullous pemphigoid (BP) associated with milia lesions has been increasingly reported, but its prevalence has not been reported in a Brazilian BP population yet. OBJECTIVES: To describe the occurrence and clinical-laboratorial findings of BP-milia association in a southeastern Brazilian sample. METHODS: …

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Autoantibodies against desmoglein 2 are not pathogenic in pemphigus

Marcela Calixto Brandão Miguel, Tamíris Amanda Júlio, Sebastián Vernal, Natália Aparecida de Paula et autres

BACKGROUND: Anti-desmoglein 1 and 3 autoantibodies justify acantholysis in pemphigus; however, the pathogenesis of anti-desmoglein 2 is hypothetical. OBJECTIVE: To compare the participation of desmogleins 1, 2 and 3 through the production of serum autoantibodies, and protein and gene expression in the …

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Mimetismo molecular entre as proteínas hemidesmossomais BP180/BP230 e isoformas neuronais na associação do penfigoide bolhoso com a demência

Tamíris Amanda Júlio

Autoanticorpos direcionados contra as proteínas hemidesmossomais BP180 e/ou BP230, expressas na zona da membrana basal do tegumento, causam penfigoide bolhoso (PB).A associação do PB com a demência tem sido cada vez mais relatada em idosos.Tendo conhecimento de (i) a presença de anticorpos …

Molecular mimicry between BP180/BP230 hemidesmosomal proteins and neural isoforms in the association of bullous pemphigoid with dementia

Tamíris Amanda Júlio

Autoanticorpos direcionados contra as proteínas hemidesmossomais BP180 e/ou BP230, expressas na zona da membrana basal do tegumento, causam penfigoide bolhoso (PB). A associação do PB com a demência tem sido cada vez mais relatada em idosos. Tendo conhecimento de (i) a presença …

Imiquimod-Associated Pemphigus Foliaceus

Marcela Rosa de Almeida Farid, Helena Barbosa Lugão, Tamíris Amanda Júlio, Eduardo Antônio Donadi et autres

Farid, Marcela Rosa de Almeida MD; Lugão, Helena Barbosa MD, PhD; Julio, Tamiris Amanda MSc; Donadi, Eduardo Antônio MD, PhD; Bueno Filho, Roberto MD, PhD; Roselino, Ana Maria MD, PhD Author Information

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Biological predictors shared by dementia and bullous pemphigoid patients point out a cross-antigenicity between BP180/BP230 brain and skin isoforms

Tamíris Amanda Júlio, Sebastián Vernal, Juliana Doblas Massaro, Matheus Costa e Silva et autres

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Bullous Pemphigoid Associated with Ischemic Cerebrovascular Accident and Dementia: Exclusive Blistering Lesions on the Upper Hemiparetic Limb.

Sebastián Vernal, Tamíris Amanda Júlio, Norito Ishii, Takashi Hashimoto et autres

Bullous pemphigoid (BP) has been associated with neurological disorders (NDs), which has led to the hypothesis that molecular mimicry exists between hemidesmosomal proteins and neuronal peptides. A 79-year-old hemiparetic woman presented with tense bullae affecting exclusively her right paretic upper limb for …

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Anti‐desmogleins autoantibodies detected by ELISA and blotting in bullous pemphigoid: what do they mean?

Tamíris Amanda Júlio, Sebastián Vernal, Aline Turatti, Ana Maria Ferreira Roselino

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Marcadores sorológicos Bullous Pemphigoid 180/230 e fator neurotrófico derivado do cérebro (BDNF) na relação penfigoide bolhoso e demência

Tamíris Amanda Júlio

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SOLID-STATE STABILITY AND SOLUBILITY DETERMINATION OF CRYSTALLINE FORMS OF MOXIFLOXACIN HYDROCHLORIDE

Tamíris Amanda Júlio, Jerusa S. Garcia, Rudy Bonfílio, Magali Benjamim Araújo et autres

Objective: This study aims to evaluate possible crystalline changes that can occur with MOX under the influence of temperature and relative humidity (RH) as well as to determine the relative solubility of the observed crystalline forms. Methods: Thermoanalytical methods with the support …

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Compatibility and stability of valsartan in a solid pharmaceutical formulation

Tamíris Amanda Júlio, Igor Fernando Zâmara, Jerusa S. Garcia, Marcello G. Trevisan

Valsartan (VAL) is a highly selective blocker of the angiotensin II receptor that has been widely used in the treatment of hypertension. Active pharmaceutical ingredient compatibility with excipients (crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose and titanium dioxide) is usually evaluated in solid …

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