Pierre-François D’Haese

Neuromodulation in Alzheimer’s disease: a review with illustrative pilot data using focused ultrasound

Marc W. Haut, Camila Vieira Ligo Teixeira, Manish Ranjan, Jeffrey Carpenter et autres

us (code pays fourni par la source)

Bridging the outcome documentation gap in epilepsy surgery: Validating large language model agents for automated Engel and International League Against Epilepsy scoring from clinical notes

P. David Adelson, Haley Delaney, Pierre-François D’Haese

OBJECTIVE: Timely and accurate classification of postepilepsy surgery outcomes using Engel and International League Against Epilepsy (ILAE) scales is essential for clinical follow-up, yet electronic health record documentation often lacks the structured detail needed for reliable scoring. This study aimed to validate …

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Principles of Physiologic Closed-Loop Controllers in Neuromodulation

Victoria S. Marks, Joram J. van Rheede, Dean M Karantonis, Rosana Esteller et autres

RATIONALE: As neurostimulation devices increasingly incorporate closed-loop functionality, the greater design complexity brings additional requirements for risk management and special considerations to optimize benefit. This manuscript creates a common framework on which all current and planned neuromodulation-based physiologic closed-loop controllers (PCLCs) can …

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EP.04.42 Alunghive: Autonomous Registry and Analytics System to Transform Clinical Workflow and Enable Multicenter Lung Cancer Screening Research

Michael N. Kammer, Pierre-François D’Haese, Fabien Maldonado

fr, us (code pays fourni par la source)

A case report of focused ultrasound neuromodulation of the bilateral nucleus accumbens for methamphetamine use disorder.

James J. Mahoney, Daisy G.Y. Thompson-Lake, Manish Ranjan, Jennifer L. Marton et autres

Nearly 2 million people had a diagnosis of methamphetamine use disorder (MUD) in 2023 and overdose deaths involving psychostimulants are increasing. Given that there are no currently approved U.S. Food and Drug Administration medications for MUD, novel treatments are needed to complement …

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Navigational Bronchoscopy or Transthoracic Needle Biopsy for Lung Nodules

Robert J. Lentz, Katherine Frederick-Dyer, Virginia B. Planz, Tatsuki Koyama et autres

BACKGROUND: Each year, millions of pulmonary nodules are identified incidentally or through lung cancer screening, and many involve biopsy to distinguish cancer from benign processes. Both navigational bronchoscopy and computed tomography-guided transthoracic needle biopsy are commonly used in patients undergoing biopsies of …

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Focused Ultrasound Neuromodulation: Exploring a Novel Treatment for Severe Opioid Use Disorder

Ali R. Rezai, Daisy G.Y. Thompson-Lake, Pierre-François D’Haese, Nathalie H. Meyer et autres

BACKGROUND: Opioid use disorder remains a critical health care challenge because current therapeutic strategies have limitations that result in high recurrence and deaths. We evaluated the safety and feasibility of focused ultrasound (FUS) neuromodulation to reduce substance cravings and use in severe …

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Memory Consolidation, Brain Atrophy, and Metabolism in Amyloid Positive and Negative Amnestic Mild Cognitive Impairment

Camila Vieira de Ligo Teixeira, Cierra M. Keith, Marc W. Haut, Rashi I. Mehta et autres

Abstract Background The existing literature has established that Alzheimer's disease (AD) is typically characterized by changes in memory‐associated temporal and parietal lobe atrophy and hypometabolism. However, some individuals clinically diagnosed with AD do not have biomarkers consistent with AD pathology. In this …

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The role of the insula predicting memory performance in Alzheimer's disease amyloid positive and negative: a clinical cohort study

Michelle M. Coleman, Marc W. Haut, Camila Vieira de Ligo Teixeira, Cierra M. Keith et autres

Abstract Background Known areas of Alzheimer’s pathology, including the hippocampus, entorhinal cortex and medial temporal cortex, have been well‐demonstrated as demonstrating atrophy in Alzheimer’s disease (AD). Using surface‐based morphometry measures, recent studies have suggested that the insula may play a role in …

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Navigational Bronchoscopy Versus Computed Tomography-guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules: Initial Results From the VERITAS Multicenter Randomized Trial

Robert J. Lentz, Katherine Frederick-Dyer, Virginia B. Planz, Tatsuki Koyama et autres

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Navigational Bronchoscopy vs CT Scan-Guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules

Robert J. Lentz, Katherine Frederick-Dyer, Virginia B. Planz, Tatsuki Koyama et autres

Background: Lung nodule incidence is increasing. Many nodules require biopsy to discriminate between benign and malignant causes. The gold standard for minimally invasive biopsy, CT scan-guided transthoracic needle biopsy (CT-TTNB), has not been compared directly with navigational bronchoscopy, a method that recently …

us, cn, gb (code pays fourni par la source)

Navigational Bronchoscopy versus Computed Tomography-guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules: protocol and rationale for the VERITAS multicenter randomized trial

Robert J. Lentz, Katherine Frederick-Dyer, Virginia B. Planz, Tatsuki Koyama et autres

Background: Lung nodule incidence is increasing. Many nodules require biopsy to discriminate between benign and malignant etiologies. The gold-standard for minimally invasive biopsy, computed tomography-guided transthoracic needle biopsy (CT-TTNB), has never been directly compared to navigational bronchoscopy, a modality which has recently …

us, cn, gb (code pays fourni par la source)