Mirza Muhammad Hadeed Khawar

Diagnostic yield and safety of small versus standard cryoprobes in transbronchial lung cryobiopsy for interstitial lung disease: a systematic review and meta-analysis

Dua Bashir, Aisha Bashir, Taimoor Hassan, Aizaz Ali et autres

Abstract Background Interstitial lung diseases (ILDs) are a heterogeneous group of conditions that frequently require histopathology for a confident diagnosis. Transbronchial lung cryobiopsy (TBLC) is a minimally invasive alternative to surgical lung biopsy, but evidence comparing small-diameter and standard-diameter cryoprobes remains fragmented, …

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Additional file 1 of Diagnostic yield and safety of small versus standard cryoprobes in transbronchial lung cryobiopsy for interstitial lung disease: a systematic review and meta-analysis

Dua Bashir, Aisha Bashir, Taimoor Hassan, Aizaz Ali et autres

Supplementary Material 1.

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Additional file 1 of Diagnostic yield and safety of small versus standard cryoprobes in transbronchial lung cryobiopsy for interstitial lung disease: a systematic review and meta-analysis

Dua Bashir, Aisha Bashir, Taimoor Hassan, Aizaz Ali et autres

Supplementary Material 1.

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Temporal Trends and Disparities in Liver Cell Carcinoma and Hepatic Failure Mortality in the United States: A 24-Year Analysis from CDC WONDER, 1999-2023

Saba Khan, Muneeb Khawar, Muhammad Haris Khan, Salman Ayub Jajja et autres

Background: Liver cell carcinoma (LCC) and hepatic failure (HF) are significant contributors to liver-related mortality in the United States. This study assessed LCC- and HF-related mortality trends (1999–2023) using CDC WONDER data, stratified by demographics and geography. Methods: Deaths among U.S. adults …

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Risk factors for developing acute kidney injury after heart transplant: A systematic review and meta-analysis

Muneeb Khawar, Ayesha Sehar, Manahil Shahzad, Hasnain Farooq et autres

BACKGROUND Acute kidney injury (AKI) is a common and serious complication following heart transplantation, significantly impacting patient outcomes and survival rates. AKI after transplantation can lead to prolonged hospital stays, increased morbidity, and even mortality. AIM To identify and quantify significant risk …

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Clinicopathological predictors of right para esophageal lymph node metastasis in papillary thyroid carcinoma: A systematic review and meta-analysis

Mirza Muhammad Hadeed Khawar, M S Cheema, Muneeb Khawar, Muhammad Huzaifa Ahmed Khan et autres

BACKGROUND Dissection of the right paraesophageal lymph node (RPELN) in managing papillary thyroid carcinoma remains a contentious issue. This meta-analysis assesses previously established and novel risk factors associated with RPELN metastasis. AIM To evaluate previously established and novel risk factors associated with …

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Abstract 4362395: Efficacy of Mavacamten Combined with Standard Therapy in Hypertrophic Obstructive Cardiomyopathy: A Retrospective Cohort Study

Abdul Qadeer, Mohamed R. Fouad, Muneeb Khawar, Prutha Pathak et autres

Background: Hypertrophic obstructive cardiomyopathy (HOCM) is usually treated with standard therapy: beta-blockers (BBs) and/or non-dihydropyridine calcium channel blockers (CCBs). Mavacamten, a selective cardiac myosin inhibitor, has shown efficacy in improving functional status and reducing obstruction. Research Question: Does the addition of Mavacamten …

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Abstract 4373072: Evaluating the Outcomes and Complications of Implantable Cardioverter Defibrillator Therapy in Hypertrophic Cardiomyopathy

Muneeb Khawar, Mirza Muhammad Hadeed Khawar, Ali Sohail, Muhammad Muneeb Khawar et autres

Background: Implantable cardioverter-defibrillators (ICDs) are critical for preventing sudden cardiac death in patients with hypertrophic cardiomyopathy (HCM). However, ICD implantation is associated with risks, including inappropriate therapy, lead failure, and pocket bleeding, which may impact patient outcomes. Research Question: What are the …

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Ropeginterferon alfa-2b vs standard therapy in polycythemia vera: A meta-analysis of efficacy and safety outcomes

Leo Tom, Mina Nan, Shruti Manoj Mundada, Basel Al Khatib et autres

BACKGROUND Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by excessive blood cell production, which increases the risk of thrombosis. Ropeginterferon alfa-2b (RI) offers potential advantages over standard therapy (ST; including phlebotomy, hydroxyurea, and aspirin) by achieving hematologic and molecular responses. However, …

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Posterior pericardiotomy: An effective strategy for reducing post-coronary artery bypass grafting complications, with considerations for pleural effusion risk

Muneeb Khawar, Syed Abdullah Shah, Ayesha Khan, Hanan E Saeed et autres

BACKGROUND Postoperative complications such as atrial fibrillation and pericardial effusion are frequent after coronary artery bypass grafting (CABG), contributing to increased morbidity and prolonged hospital stays. Posterior pericardiotomy (PP), a surgical technique involving incision of the posterior pericardium to allow drainage, has …

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Thoracic endovascular vs open surgical repair in descending thoracic aortic aneurysms: A systematic review and meta-analysis

Muneeb Khawar, Majeeda Rasheed, Syed Abdullah Shah, Sarmad Zain et autres

BACKGROUND Descending thoracic aortic aneurysms are dangerous and have to be treated quickly. The primary treatment methods are thoracic endovascular aortic repair (TEVAR) and open surgical repair (OSR). The comparative effectiveness and safety of TEVAR and OSR were evaluated in this meta-analysis, …

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EPIDEMIOLOGICAL TRENDS IN ACUTE RESPIRATORY DISTRESS SYNDROME AND RESPIRATORY FAILURE MORTALITY: AN ANALYSIS OF DEMOGRAPHIC AND REGIONAL VARIATIONS (1999-2023)

Saba Khan, Prutha Pathak, Mirza Muhammad Hadeed Khawar, ABDUL QADEER et autres