Accès ouvert
2026
article
OpenAlex
Е. Н. Карева, О. M. Oleynikova, S. Yu. Serebrova, Ирина Николаевна Кононова et autres
Обзор посвящен развитию антиэстрогеновых лекарственных средств: переходу от стандартных схем (избирательные модуляторы рецепторов эстрогенов, ингибиторы ароматазы) к инновационным стратегиям с использованием селективных индукторов деградации эстрогеновых рецепторов (SERD). В фокусе — мишени действия новых антиэстрогенов, механизмы развития резистентности к ним клеток и возможные …
us
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2019
article
OpenAlex
О. M. Oleynikova, A. A. Sarapulova, G. N. Avakyan
Objective: to study the effect of blue polarizing glasses on photosensitivity in patients with photosensitive epilepsy (PSE). Materials and methods. On the backdrop of red light stimulation, EEG and daytime video EEG recordings were performed in 19 patients with epilepsy (15 women, …
ru, us
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Accès ouvert
2018
article
OpenAlex
Yu. V. Rubleva, R A Teryan, G. G. Аvakyan, А. А. Савенков et autres
Objective. To conduct a survey of adult patients with focal epilepsy and ictal disturbances of cardiac rhythm and conduction, considering the disease classification, anamnesis, clinical, electroencephalographic and neuroimaging data. Materials and methods . We selected 70 patients aged 18 to 51 years …
ru
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Accès ouvert
2018
article
OpenAlex
О. M. Oleynikova, А. А. Савенков, Gayane Avagyan, М. А. Богомазова et autres
The aim was to study the seasonal birth rates of epileptic patients. Materials and methods. Case reports of 6934 patients with epilepsy in three districts of Moscow and one medical center were analyzed. The distribution of patients according to the forms of …
ru
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Accès ouvert
2016
article
OpenAlex
G. N. Avakyan, Л. Н. Неробкова, О. M. Oleynikova, Т. А. Воронина et autres
Possibilities of application the prolonged form valproic acid and antioxidant in secondary - generalized seizures was investigated in experiment and in clinical study in patients with epilepsy. In rats with cobalt-induced epilepsy their efficacy has been revealed by the suppression of determinant …
ru
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Accès ouvert
2016
article
OpenAlex
О. M. Oleynikova, Е. Н. Карева, М. А. Богомазова, G. N. Avakyan et autres
The pineal gland hormone melatonin is the main regulator of biological rhythms. It affects sleep, brain bioelectric activity and seizures. The majority of experimental and clinical studies are confirmed the anticonvulsant properties of melatonin. However, in the scientific literature there is no …
ru
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Accès ouvert
2012
article
OpenAlex
Е. Н. Карева, О. M. Oleynikova, В. О. Панов, N. L. Shimanovskiy et autres
Recent data upon molecular mechanisms of pleiotropic action of estrogens in human brain is presented in the article. Given detailed descriptions of properties of classical and membrane bound estradiol receptors, that maintain gene expression regulation, modulation of neurotransmittent systems and signal cascade …
ru
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