Blanka Adamová

Spinal muscular atrophy with five SMN2 copies: Phenotypic heterogeneity and implications for newborn screening and treatment decisions

Olesja Parmová, Blanka Adamová

Background The severity of spinal muscular atrophy (SMA) is partially influenced by SMN2 copy number, although this relationship becomes less reliable at higher copy numbers. The implementation of newborn screening has led to increasing identification of presymptomatic infants with five SMN2 copies, …

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Lumbar paraspinal muscles in patients with chronic non-specific low back pain and the effect of exercise: comparative and interventional study

Viktória Kokošová, Daniela Vlažná, Peter Krkoška, Michaela Sládečková et autres

Background: Lumbar paraspinal muscles (LPM), which belong to lumbar extensor muscles, play a key role in stabilising the lumbar spine and maintaining spine health. Although chronic non-specific low back pain (CNLBP) represents a major health problem worldwide, there is a knowledge gap …

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Comparison of hybrid guided home-based and outpatient rehabilitation in patients with chronic low back pain: A randomized controlled trial

Filip Dosbaba, Vojtech Senkyr, Daniela Vlažná, Jitka Minarikova et autres

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The effect of regular exercise on the clinical status and paraspinal muscles of patients with chronic non-specific low back pain

Blanka Adamová, Daniela Vlažná

Quantitative magnetic resonance imaging parameters of lumbar paraspinal muscles and their relationship to function and ageing in healthy subjects

Viktória Kokošová, Peter Krkoška, Daniela Vlažná, Marek Dostál et autres

Muscle ageing involves structural and functional changes of muscles, mainly their replacement by fatty and fibrous tissue accompanied by the loss of muscle function. Quantitative magnetic resonance imaging (qMRI) methods have potential to provide biomarkers of degenerative changes in muscles with ageing. …

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Quantitative magnetic resonance imaging parameters of lumbar paraspinal muscle impairment in myotonic dystrophy type 2 and their evolution with aging

Viktória Kokošová, Peter Krkoška, Daniela Vlažná, Michaela Sládečková et autres

Introduction: Muscle magnetic resonance imaging (MRI) is an emerging method in the diagnosis and monitoring of muscular dystrophies. This cross-sectional, comparative study aimed to evaluate quantitative MRI (qMRI) parameters of the lumbar paraspinal muscles (LPM) in myotonic dystrophy type 2 (DM2), to …

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Strength and endurance of the lumbar extensor muscles and their predictors: A cross-sectional study in healthy subjects

Daniela Vlažná, Blanka Adamová, Peter Krkoška, Viktória Kokošová et autres

The purpose of this cross-sectional study was to present the values of maximal isometric lumbar extensor muscle strength (MILEMS) and lumbar extensor muscle endurance (LEME) in healthy subjects and to study the influence of physiological factors on these parameters. MILEMS using a …

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Cutaneous ischemia and vertebral body infarction indicating spinal cord ischemia

Karolína Vavrušová, Lucia Bakošová, Eva Vlčková, Zuzana Pazdičová et autres

Assessment of lumbar paraspinal muscle morphology using mDixon Quant magnetic resonance imaging (MRI): a cross-sectional study in healthy subjects

Peter Krkoška, Viktória Kokošová, Marek Dostál, Daniela Vlažná et autres

Background: Lumbar paraspinal muscles (LPM) are a part of the deep spinal stabilisation system and play an important role in stabilising the lumbar spine and trunk. Inadequate function of these muscles is thought to be an essential aetiological factor in low back …

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Strength and Endurance of the Lumbar Extensor Muscles and Their Predictors - a Cross-Sectional Study in Healthy Subjects

Daniela Vlažná, Blanka Adamová, Peter Krkoška, Viktória Kokošová et autres

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Trunk muscle dysfunction in patients with myotonic dystrophy type 2 and its contribution to chronic low back pain

Daniela Vlažná, Peter Krkoška, Michaela Sládečková, Olesja Parmová et autres

Introduction: Myotonic dystrophy type 2 (MD2) presents with a varied manifestation. Even though the myopathy in these patients is more widespread, axial musculature involvement is one of the most prominent conditions. MD2 patients also often report chronic low back pain (CLBP). The …

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Lumbar spinal stenosis - clinical manifestation, diagnosis and therapeutic strategy

Blanka Adamová, Peter Krkoška

LumbĂĄlnĂ­ spinĂĄlnĂ­ stenĂłza (LSS) je klinicko­‑radiologickĂ˝ syndrom, nejnovějĹĄĂ­ definice zohledňuje klinickou manifestaci i anatomickĂŠ změny (zúŞenĂ­ pĂĄteřnĂ­ho kanĂĄlu). PřevaĹžujĂ­cĂ­m věkem začátku potíŞí je ĹĄestĂĄ dekĂĄda. OnemocněnĂ­ bĂ˝vĂĄ poddiagnostikovĂĄno, přičemĹž přispĂ­vĂĄ k omezenĂ­ mobility starĹĄĂ­ch pacientĹŻ. MĹŻĹže se manifestovat neurogennĂ­mi klaudikacemi, radikulĂĄrnĂ­m syndromem …