Accès ouvert
2026
article
OpenAlex
Alice S. Ryan, Vincent C. Marconi, Brandon C. Briggs, Alicia J. Lozano et autres
Abstract Background People with HIV (PWH) represent a high-risk patient group that will benefit from easily accessible exercise programs, particularly those centered on high intensity. Yet, limited telerehabilitation programs are available. Methods In a 12-week randomized clinical trial of PWH ≥50 years …
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2026
conference-abstract
OpenAlex
Josseirys Valentin Rivera, Naomi Layne, Kevin Mammino, Veronica Rowe et autres
Introduction: Survivors of chronic subcortical strokes often face lower limb disabilities, leading to a sedentary lifestyle and slower walking speeds than other older adults. Increasing physical activity is vital for regaining independence, enhancing quality of life, and reducing mortality rates. Research indicates …
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2026
conference-abstract
OpenAlex
Lisa C. Krishnamurthy, Emily Smith, Anastasia Bohsali, Keith McGregor et autres
Background: Previous studies show reduced gamma-aminobutyric acid (GABA) levels in the lesioned hemisphere of chronic stroke patients, linked to poorer motor learning and impaired cortical plasticity. In healthy models, exercise increases GABA levels. This imaging study aims to evaluate the impact of …
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Accès ouvert
2026
article
OpenAlex
Tom S Novak, Caroline Quan, Keith McGregor, Kevin Mammino et autres
Exercise improves cardiovascular health in older adults, yet variability in responsiveness remains. This study tested if prescribed exercise intensity adherence predicts individual differences in cardiovascular fitness gains following an intervention. From 2017 to 2022, nineteen sedentary older adults (69.78 ± 6.47 years) …
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Accès ouvert
2026
article
OpenAlex
Keith McGregor, S. Katherine Sweatt, C. Elliott Morgan, Ayat Abdullah Ahmad Najmi et autres
Chronic post-stroke headache is a common yet understudied complication of stroke, potentially driven by maladaptive connectivity between limbic and sensorimotor brain regions. This pilot study evaluated the effects of a combined intervention using repetitive transcranial magnetic stimulation (rTMS) and moderate-intensity exercise on …
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Accès ouvert
2026
preprint
OpenAlex
Keith McGregor, S. Katherine Sweatt, Charity J. Morgan, Ayat Abdullah Ahmad Najmi et autres
Chronic post-stroke headache is a common yet understudied complication of stroke, potentially driven by maladaptive connectivity between limbic and sensorimotor brain regions. This pilot study evaluated the effects of a combined intervention using repetitive transcranial magnetic stimulation (rTMS) and moderate-intensity exercise on …
us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Jamal Al Ali, J. Lucas McKay, Joe R. Nocera, Faiçal Isbaine et autres
BACKGROUND: The effect of deep brain stimulation (DBS) on gait in patients with Parkinson's disease (PD) remains variable, and prospective, long-term studies, especially involving globus pallidus interna (GPi) stimulation, are limited. OBJECTIVES: We tested the hypothesis that subthalamic nucleus (STN) and GPi …
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2025
conference-abstract
OpenAlex
Tom S Novak, Cydney Goodwin-Hamel, Risha Patel, Brandon C. Jones et autres
Background: Approximately 8.5 million US adults and 10% of veterans suffer from peripheral artery disease (PAD), the primary symptom of which is reproducible leg pain with walking (claudication) that leads to impaired mobility, loss of functional status, and increased risk of amputation. …
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Accès ouvert
2025
preprint
OpenAlex
Jamal Al Ali, J. Lucas McKay, Joe R. Nocera, Faiçal Isbaine et autres
BACKGROUND AND OBJECTIVES: The effect of deep brain stimulation (DBS) on gait in patients with Parkinson's disease (PD) is variable but prospective, long-term studies-especially including globus pallidus interna (GPi) stimulation-remain sparse. We tested the hypothesis that subthalamic nucleus (STN) and GPi DBS …
us
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
C. Kim, D. Holmes Morton, J. Lucas McKay, Joe R. Nocera et autres
Introduction: Parkinson's Disease (PD) is commonly treated with the dopamine precursor, levodopa, which is used in antiparkinsonian therapy. After several years of taking this medication, many individuals with PD experience medication-related motor fluctuations (MRMF), a.k.a., OFF-time. OFF-time is one of the most …
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Accès ouvert
2025
article
OpenAlex
Jeann L. Sabino‐Carvalho, Sabrina Li, Elsa Mekonnen, Kevin Mammino et autres
PURPOSE: Parasympathetic reactivation is essential for the rapid decrease in heart rate following exercise and delayed heart rate recovery (HRR) post-exercise is linked to poor clinical outcomes. Chronic kidney disease (CKD) is associated with autonomic dysfunction including reduced parasympathetic activity. Exercise training …
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Accès ouvert
2025
article
OpenAlex
Tom S Novak, Kevin Mammino, Medina Bello, Isabella Paredes Spir et autres
Purpose Biological aging has a profound impact on cerebral health. A prevalent factor thought to underpin overall brain health is healthy cerebrovascular function. Recent research suggests a beneficial relationship between cerebrovascular health and physical activity. Specifically, transcranial doppler (TDS) studies have shown …
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