Accès ouvert
2024
preprint
OpenAlex
José M. Uribe‐Salazar, Gulhan Kaya, KaeChandra Weyenberg, Brittany Radke et autres
Abstract The expansion of the human SRGAP2 family, resulting in a human-specific paralog SRGAP2C, likely contributed to altered evolutionary brain features. The introduction of SRGAP2C in mouse models is associated with changes in cortical neuronal migration, axon guidance, synaptogenesis, and sensory-task performance. …
us
(code pays fourni par la source)
Accès ouvert
2020
article
OpenAlex
Alexandra Colón-Rodríguez, José M. Uribe‐Salazar, KaeChandra B. Weyenberg, Aditya Sriram et autres
In recent years, zebrafish have become commonly used as a model for studying human traits and disorders. Their small size, high fecundity, and rapid development allow for more high-throughput experiments compared to other vertebrate models. Given that zebrafish share >70% gene homologs …
us
(code pays fourni par la source)
Accès ouvert
2020
preprint
OpenAlex
Alexandra Colón-Rodríguez, José M. Uribe‐Salazar, KaeChandra Weyenberg, Aditya Sriram et autres
ABSTRACT In recent years zebrafish have become commonly used as a model for studying human traits and disorders. Their small size, high fecundity, and rapid development allow for more high-throughput experiments compared to other vertebrate models. Given that zebrafish share >70% gene …
us
(code pays fourni par la source)
Accès ouvert
2016
article
OpenAlex
Aiko Iwata‐Otsubo, Brittany Radke, Seth D. Findley, Brian L. Abernathy et autres
Fluorescence in situ hybridization (FISH)-based karyotyping is a powerful cytogenetics tool to study chromosome organization, behavior, and chromosome evolution. Here, we developed a FISH-based karyotyping system using a probe mixture comprised of centromeric and subtelomeric satellite repeats, 5S rDNA, and chromosome-specific BAC …
us
(code pays fourni par la source)