Sandrine Bourgoin‐Voillard

Type I interferon signaling defines a novel disease signature in xeroderma pigmentosum C human keratinocytes

Ali Nasrallah, Hamid-Reza Rezvani, Lucid Belmudes, Sandrine Bourgoin‐Voillard et autres

Xeroderma Pigmentosum C (XPC) is a DNA damage recognition protein central to the global genome nucleotide excision repair (GG-NER) pathway, where it acts as a primary sensor of UV-induced DNA lesions. Loss-of-function mutations in the XPC gene lead to a photosensitive phenotype, …

fr, iq (code pays fourni par la source)

Type I Interferon Signaling Defines a Novel Disease Signature in Xeroderma Pigmentosum C Human Keratinocytes

Ali Nasrallah, Hamid Reza Rezvani, Lucid Belmudes, Sandrine Bourgoin‐Voillard et autres

Abstract Xeroderma Pigmentosum C (XPC) is a DNA damage recognition protein central to the global genome nucleotide excision repair (GG-NER) pathway, where it acts as a primary sensor of UV-induced DNA lesions. Loss-of-function mutations in the XPC gene lead to a photosensitive …

fr, pl, iq (code pays fourni par la source)

QUANTITATIVE PROTEOMICS OF PLASMA EXTRACELLULAR VESICLES REVEALS A TTR-PLASMINOGEN NETWORK IN ATTR CARDIAC AMYLOIDOSIS

Amira Zaroui, Damien Habert, Benoît Vallée, Mounira Kharoubi et autres

ABSTRACT Background Despite recent progress, the prognosis of patients with transthyretin (TTR) cardiac amyloidosis remains poor; this is primarily due to late diagnosis, when irreversible damage has already occurred. Today’s diagnostic work-up still relies on peripheral tissue or a cardiac biopsy, while …

fr (code pays fourni par la source)

Corrigendum to “The nucleolin antagonist N6L and paclitaxel combination treatment could be a new promising therapeutic strategy for pancreatic ductal adenocarcinoma therapy” [Eur. J. Pharmacol. 991 (2025) 177310]

Fabrice Raineri, Linda LaRue, Carina Florina Cojocaru, Benedetta Ferrara et autres

fr (code pays fourni par la source)

The nucleolin antagonist N6L and paclitaxel combination treatment could be a new promising therapeutic strategy for pancreatic ductal adenocarcinoma therapy

Fabrice Raineri, Linda LaRue, Crina M. Cojocaru, Benedetta Ferrara et autres

) particles and host molecules CD for developing carrier enabling all at once the loading of PTX (hydrophobic drug) and N6L (cationic drug). This association generates water-soluble particles capable of targeting via N6L and delivering paclitaxel to tumor cells.

fr (code pays fourni par la source)

What about markers inflammation on cardiac amyloidosis?

A. Zaroui, Gabriela Neculae, B. Mélanie, Mounira Kharoubi et autres

fr (code pays fourni par la source)

Matrix stiffness regulates the protein profile of extracellular vesicles of pancreatic cancer cell lines

Benedetta Ferrara, Sandrine Bourgoin‐Voillard, Damien Habert, Benoît Vallée et autres

Abstract The fibrotic stroma characterizing pancreatic ductal adenocarcinoma (PDAC) derives from a progressive tissue rigidification, which induces epithelial mesenchymal transition and metastatic dissemination. The aim of this study was to investigate the influence of matrix stiffness on PDAC progression by analyzing the …

it, fr (code pays fourni par la source)

Value of a secretomic approach for distinguishing patients with COVID‐19 viral pneumonia among patients with respiratory distress admitted to intensive care unit

Angélique Blangy‐Letheule, Amandine Vergnaud, Thomas Dupas, Damien Habert et autres

In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand the molecular pathophysiology of viral pneumonia and to search for …

fr (code pays fourni par la source)

Proteomic Methods to Study Autophagy in Skin Exposed to Pollutants

Mohammad Fayyad‐Kazan, Sandrine Bourgoin‐Voillard, Walid Rachidi, Michel Sève

iq, fr (code pays fourni par la source)

Evaluation de la toxicité de sous-produits de médicament par approcheprotéomique : cas du furosémide.

Sandre Fidji, Sandrine Bourgoin‐Voillard, Benoît Vallée, Damien Habert et autres

International audience

fr (code pays fourni par la source)

Complete title: Value of a secretomic approach for distinguishing patients with COVID-19 viral pneumonia among patients with respiratory distress admitted to intensive care unit Shortened title: Secretomic to distinguish COVID-19 patients

Angélique Blangy‐Letheule, Amandine Vergnaud, Thomas Dupas, Damien Habert et autres

Introduction : In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with non-viral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand the molecular pathophysiology of viral pneumonia and to …

fr (code pays fourni par la source)

Proteomics approach for evaluating metabolites toxicity of furosemide, a widely-used diuretics.

Sandre Fidji, Sandrine Bourgoin‐Voillard, Benoît Vallée, Damien Habert et autres

International audience

fr (code pays fourni par la source)