Viveka P. Jyotsna

Prediction of First-Year Growth Velocity Response to Growth Hormone Therapy in Patients with Growth Hormone Deficiency

Ravindranath K. Reddy, Manasvini Bhatt, Vanshja Pandit, Aashima D. Gupta et autres

Abstract Introduction: First-year growth response to biosynthetic growth hormone (GH) largely varies between populations. We aimed to predict first-year growth response to growth hormone replacement therapy (GHRT) in children with growth hormone deficiency (GHD). Methods: Growth response during the first year of …

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Nurse-led intervention on knowledge and awareness regarding chronic kidney disease among hypertensive and/or diabetic patients: A quasi-experimental study

Jyoti Jangid, Manju AK Rajora, Rajiv Narang, Viveka P. Jyotsna

Background: Diabetes and hypertension are the leading causes of chronic kidney disease (CKD) worldwide, and adequate awareness is crucial for its prevention and early detection among high-risk populations. Objective: To evaluate the effectiveness of a nurse-led educational program through a booklet on …

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P31 - Bilateral adrenalectomy as primary surgical treatment modality for Cushing syndrome – 10 years’ experience from tertiary care centre

Bhawna Attri, Alpesh Goyal, Mani Kalaivani, Devika Kandasamy et autres

Abstract Background/Introduction Bilateral adrenalectomy (BLA) is often deemed as last resort in the management of patients with Cushing sundrome (CS). However, it is a lifesaving procedure in severe endogenous hypercortisolism and palliative therapy in those with metastatic disease. Data describing the utility …

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Clinical Profile and Treatment Outcomes of Tumour-Induced Osteomalacia – A Single-Centre Experience

Prashiddha Dhakal, Alpesh Goyal, Viveka P. Jyotsna, Ashutosh Kumar Arya et autres

Introduction: Tumour-induced osteomalacia (TIO) is rare. At our referral centre, we see a substantial number of TIO. Therefore, we planned to study their profile and treatment outcomes to provide insight in management. Methods: = 12; occult tumour and negative genetic testing for …

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83P Metabolic health of Indian women with breast cancer and its relation with other known prognostic and predictive factors of breast cancer

P. Shukla, S. V. S. Deo, Amar J. Gajjar, Vathulru Seenu et autres

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Two families, two pathways: a case series of 46, XY DSD with 17α-hydroxylase deficiency and isolated 17,20-lyase deficiency due to novel CYB5A variant

Rakesh Kumar Garg, Manasvini Bhatt, Ashutosh Kumar Arya, Viveka P. Jyotsna et autres

Abstract Objectives 17α-Hydroxylase and 17,20-lyase are enzymes encoded by the CYP17A1 gene mapped at chromosome 10q, and are required for the synthesis of sex steroids and cortisol. 17α-hydroxylase deficiency causes a decrease in cortisol and androgen with a subsequent overproduction of adrenocorticotrophic …

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Delayed Presentation of Thyroid Storm Postradioiodine Ablation: Case Report and Review of Literature

Yogita Khandelwal, Preeti Vijay Namjoshi, Jeepalem Sai Moulika, Bela Jain et autres

Thyroid storm is an acute life-threatening complication of hyperthyroidism that presents with multisystem involvement. It can be precipitated by radioiodine therapy in high-risk patients. It has become less frequent, as current therapeutic approaches (antithyroid drugs and beta blockers) prevent the impact of …

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Trends in Presentation and Management of Endogenous Hyperinsulinaemic Hypoglycaemia Over the Last Three Decades at a Tertiary Care Centre (1992–2022)

Setu Gupta, Alpesh Goyal, Devasenathipathy Kandasamy, Shipra Agarwal et autres

Introduction: Endogenous hyperinsulinaemic hypoglycaemia (EHH) is characterized by inappropriate insulin secretion from pancreatic beta cells despite low blood glucose concentrations. We aimed to evaluate the secular changes in presentation and management of EHH due to insulinoma/non-insulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) at our …

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Cross-Reactivity of Insulin Immunoassays Important for Insulin Analogue Detection in Factitious Hypoglycaemia

Sachin K. Raj, Setu Gupta, Alpesh Goyal, Viveka P. Jyotsna

Sir, Read with interest the article by Deep Dutta et al.[1] where they described the efficacy of lispro insulin in diabetes. With the increasing use of insulin analogues, a new dimension has been added to the diagnosis of factitious hypoglycaemia. We recently …

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A Randomized Controlled Trial of Intrathecal versus Caudal Morphine-Bupivacaine on Postoperative Analgesia and Cortisol Levels in Pediatric Patients

Neha Pangasa, Rajeshwari Subramaniam, Gunjan Singh, Mani Kalaivani et autres

BACKGROUND: Morphine is commonly used in pediatric caudal blocks. We compared the analgesic efficacy and effect on cortisol levels of intrathecal morphine and bupivacaine with caudal morphine and bupivacaine in children undergoing lower abdominal surgeries. METHODS: Forty children undergoing lower abdominal surgeries …

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Utility of an in-house real-time PCR in whole blood samples as a minimally invasive method for early and accurate diagnosis of invasive mould infections.

Mragnayani Pandey, Immaculata Xess, Janya Sachdev, Neha Sharad et autres

INTRODUCTION: Invasive mould infections (IMIs) are a leading cause of death in patients with compromised immune systems. Proven invasive mould infection requires detection of a fungus by histopathological analysis of a biopsied specimen, sterile culture, or fungal DNA amplification by PCR in …

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Pragmatic Evaluation of Growth Hormone Stimulation Tests in Short Stature

Rahul Gupta, Aashima Dabas, Shweta Kohli, Rekha Ramot et autres

Introduction: To assess the performance of growth hormone stimulation tests (GHSTs) in the evaluation of short stature. Methods: It was a single-centre retrospective study carried out in children evaluated for short stature between January 2005 to March 2020. The clonidine stimulation test …

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