Leon Ruiter-Lopez

Opposing Roles of CYP2E1 and ALDH2 in Binge Alcohol-Mediated Cerebellar Damage

Leon Ruiter-Lopez, Wiramon Rungratanawanich, Byoung‐Joon Song

To explore the opposing roles between the toxic acetaldehyde-producing enzyme Cytochrome P450-2E1 (CYP2E1) and acetaldehyde-clearing protein mitochondrial Aldehyde Dehydrogenase-2 (ALDH2) in alcohol-mediated cerebellar damage, two separate experiments were conducted. Young Svj/129 wild-type (WT) vs. Cyp2e1-Knockout (KO) mice were administered consecutive doses of …

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Acceptability of a Brain-Injury-Tailored Yoga and Meditation Program Among Female Patients with Concussion

Hemika Vempalli, Nabeeha Jabir Affan, Katherine Snedaker, Y. Chen et autres

Background:Although concussion symptoms often resolve within 4–6 weeks, for a minority of patients, persistent postconcussion symptoms (PPCS), such as headaches, fatigue, and mood disturbances, may continue for months or years following a head injury. Rehabilitation of this group—often female—is crucial for reducing …

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Roles of Oxidative Stress and Autophagy in Alcohol-Mediated Brain Damage

Leon Ruiter-Lopez, Mohammed Abdul Sattar Khan, Xin Wang, Byoung‐Joon Song

Excessive alcohol consumption significantly impacts human health, particularly the brain, due to its susceptibility to oxidative stress, which contributes to neurodegenerative conditions. Alcohol metabolism in the brain occurs primarily via catalase, followed by CYP2E1 pathways. Excess alcohol metabolized by CYP2E1 generates reactive …

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Resilience and Concussion Recovery in Minority Women: Promoting Health Equity

Leon Ruiter-Lopez, Jack K. Donohue, Hemika Vempalli, Rebecca C. Thurston et autres

Resilience is associated with the degree to which post-concussion symptoms (PCS) are experienced. However, the role of resilience in the recovery trajectory of minority women, who tend to have prolonged concussion recovery, is poorly characterized. We evaluated the association between resilience and …

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Implications of genome plasticity for drug development

Sandra López‐León, Yeimy González‐Giraldo, Leon Ruiter-Lopez, Talía Wegman-Ostrosky

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Contributors

Ibitayo Abigail Ademuwagun, Reem Akika, Ayyappan Anitha, Olufemi Aromolaran et autres

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Predatory journals: Do not judge journals by their Editorial Board Members

Leon Ruiter-Lopez, Sandra López‐León, Diego A. Forero

Objective: Given that often the quality of journals is based on its editors, the objective of this study was to describe quantitatively the profiles of members of editorial boards (MEBs) of presumed predatory journals.Methods: The following information was retrieved from 1015 editors …

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Psychotropic medication in children and adolescents in the United States in the year 2004 vs 2014

Sandra López‐León, Manuel I. Lopez-Gomez, Barbara Warner, Leon Ruiter-Lopez

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