Hannatu Tarfa

The interplay between loneliness, cortisol, and NK cell function: The role of cortisol in NK cell dysfunction

Abhinav Saurabh, Yvonne Baumer, Laurel Mendelsohn, Elizabeth M Aquino Peterson et autres

Chronic psychosocial stressors contribute to cardiovascular disease (CVD) and related risk factors, particularly in under-resourced communities. Psychosocial stressors activate the hypothalamic-pituitary-adrenal (HPA) axis, leading to sustained cortisol action on immune cells. Natural killer (NK) cells are altered in distribution and function in …

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Abstract Tu0085: A Potential Role for NKG2D, an NK cell receptor, in Accelerated CVD risk in African American Women Living in More Adverse Neighborhood Conditions: Data From the Step It Up Physical Activity Digital Health-Enabled, Community-Engaged Intervention

Andrew Baez, Yvonne Baumer, Ayushi Dave, Abhinav Saurabh et autres

Background: Obesity and hyperlipidemia disproportionally affect African American (AA) women due to lifelong exposure to adverse social determinants of health (SDoH), leading to greater cardiovascular disease (CVD) risk. CVD risk factors and adverse SDoH are linked to poor immune health, particularly dysfunctional …

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Abstract 4140142: Neighborhood Perceptions Associate with Lipid Biomarkers in African-American Women with Cardiovascular-Kidney-Metabolic Syndrome: Data from the Step It Up Digital Health-Enabled, Community-Engaged Physical Activity Intervention

Sandy Reynolds, Marcus R. Andrews, Yvonne Baumer, Dana Sandler et autres

Background: Cardiovascular-kidney metabolic (CKM) syndrome is exacerbated among individuals experiencing chronic exposure to both environmental and psychosocial stressors. Both neighborhood and individual-level stressors increase chronic inflammation resulting in worsened CKM factors, such as hypertension, diabetes, and dys/hyperlipidemia. However, associations between neighborhood perceptions …

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Abstract 17: Associations Between Digital Health App Engagement and Physical Activity Among African American Women With Cardiovascular-Kidney-Metabolic Syndrome: Data From the Step It Up Digital Health-Enabled Physical Activity Intervention

Manuel A Cintron, James Troendle, Mario A. Pita, Hannatu Tarfa et autres

Background: Physical activity (PA) improves cardiovascular-kidney-metabolic health (CKMH); however, few digital health tools to increase PA are tailored for populations disproportionately impacted by adverse social determinants, such as African American (AA) women. Less is known about the effects of engagement with digital …

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Abstract 14087: Physical Activity is Associated With Monocytes and Monocyte Subsets in Low-Resourced Neighborhoods: Data From the Step It Up Physical Activity Intervention

Abhinav Saurabh, Hannatu Tarfa, Yvonne Baumer, Ayushi Dave et autres

Background: Physical activity (PA) reduces cardiovascular disease (CVD) risk; those living in lower-resourced neighborhoods have higher CVD risk in part due to limited PA access. Monocyte subsets (classical, intermediate, and non-classical) with their platelet aggregates (PlAgg) are key in CVD, but less …

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Abstract 14051: The Associations Between Loneliness and Circulating Lipoproteins as Well as Diabetes Risk in African-American Women Residing in Resource-Limited Neighborhoods: Data From the Step It Up Physical Activity Intervention

Sandy Reynolds, Yvonne Baumer, Ayushi Dave, Manuel Cintron et autres

Background: Loneliness is a public health crisis and recent reports suggest that people suffering from loneliness have increased cardiovascular disease (CVD) risk. A potential link between loneliness and CVD is an atherogenic shift in the lipoprotein profile. We investigated associations between loneliness …

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Abstract 18248: Physical Activity and Nutrition Self-Efficacy Associates With Perceived Everyday Discrimination in African American Women: The Step It Up Physical Activity Intervention

Foster Osei Baah, Yvonne Baumer, Hannatu Tarfa, Ayushi Dave et autres

Background: Increased self-efficacy facilitates health promoting behaviors such as physical activity (PA). Perceived discrimination may limit PA among minoritized populations, but little is known about the relationship between PA and nutrition self-efficacy (PANSE) and perceived discrimination (PD) among African American (AA) women …

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Social determinants of health, health disparities, and adiposity

Andrew S. Baez, Lola R. Ortiz-Whittingham, Hannatu Tarfa, Foster Osei Baah et autres

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Abstract 370: Corticosterone-mediated Associations Between Neighborhood Environment Perceptions and Lysosomal Acid Lipase Levels - Data From The Washington, D.C. Cardiovascular Health and Needs Assessment

Yvonne Baumer, Lola Ortiz-Whittingham, Manuel A Cintron, Hannatu Tarfa et autres

Experiences of adverse social determinants of health (SDoH), like less favorable neighborhood environment perceptions, are associated with cardiovascular disease (CVD). Lysosomal acid lipase (LAL) plays an important role in lipid metabolism, and genetic LAL deficiency has been linked to CVD risk. We …

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Customizing Place-Tailored Messaging Using a Multilevel Approach: Pilot Study of the Step It Up Physical Activity Mobile App Tailored to Neighborhood Environment

Nithya Vijayakumar, Sam J Neally, Kameswari Potharaju, Kaveri Curlin et autres

Given the community-centered nature of this pilot intervention, it was crucial to interact directly with com-

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