Gabriele Brondino

Pilot study to relate clinical outcome in pancreatic carcinoma and angiogenic plasma factors/circulating mature/progenitor endothelial cells: Preliminary results

Barbara Vizio, Anna Novarino, Alice Giacobino, Carmen Cristiano et autres

Circulating endothelial cells (CEC) and bone marrow-derived endothelial progenitors (ECP) play important roles in tumor growth and have been proposed as non-invasive markers of angiogenesis. However, CEC and ECP levels have not been investigated in pancreatic carcinoma patients. Using four-color flow cytometry …

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IL-18 Paradox in Pancreatic Carcinoma: Elevated Serum Levels of Free IL-18 are Correlated With Poor Survival

Anna Carbone, Barbara Vizio, Anna Novarino, Francesco Mauri et autres

The role of the proinflammatory interleukin (IL)-18 in cancer progression remains controversial; we thus examined the hypothesis that impaired antitumor immune response in pancreatic carcinoma patients is related to elevated levels of its natural inhibitor IL-18 binding protein (BP) and/or to alteration …

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Primary Duodenal Adenocarcinoma

Mario Solej, Silvia D’Amico, Gabriele Brondino, Marco Ferronato et autres

AIMS AND BACKGROUND: Primary duodenal adenocarcinoma is a rare tumor with a poorly defined natural history and prognostic factors. It presents with nonspecific symptoms, and for this reason the diagnosis is often delayed. It is a serious problem for the surgeon because …

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Transforming Growth Factor-β Binding Receptor Endoglin (CD105) Expression in Esophageal Cancer and in Adjacent Nontumorous Esophagus as Prognostic Predictor of Recurrence

Graziella Bellone, Dino Solerio, Luigi Chiusa, Gabriele Brondino et autres

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Prognostic impact of HER‐2/neu expression on squamous head and neck carcinomas

A Cavalot, Tiziana Martone, Nicolò Roggero, Gabriele Brondino et autres

BACKGROUND: HER-2/neu gene amplification and protein overexpression have been identified in various solid tumors, but its prognostic relevance in head and neck squamous cell carcinoma (HNSCC) is still controversial. METHODS: The study investigated the expression of HER-2/neu oncoprotein in HNSCC and sought …

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Prognostic impact of HER-2/neu expression on squamous head and neck

A Cavalot, Tiziana Martone, Nicolò Roggero, Gabriele Brondino et autres