Peihang Yu

Engineering Anti‐CRISPR Proteins to Create CRISPR‐Cas Protein Switches for Activatable Genome Editing and Viral Protease Detection

Wenyuan Kang, Fei Xiao, Xi Zhu, Xinyu Ling et autres

Proteins capable of switching between distinct active states in response to biochemical cues are ideal for sensing and controlling biological processes. Activatable CRISPR-Cas systems are significant in precise genetic manipulation and sensitive molecular diagnostics, yet directly controlling Cas protein function remains challenging. …

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Engineering Anti‐CRISPR Proteins to Create CRISPR‐Cas Protein Switches for Activatable Genome Editing and Viral Protease Detection

Wenyuan Kang, Fei Xiao, Xi Zhu, Xinyu Ling et autres

Abstract Proteins capable of switching between distinct active states in response to biochemical cues are ideal for sensing and controlling biological processes. Activatable CRISPR‐Cas systems are significant in precise genetic manipulation and sensitive molecular diagnostics, yet directly controlling Cas protein function remains …

cn (code pays fourni par la source)

The IPGA1‐ANGUSTIFOLIA module regulates microtubule organisation and pavement cell shape in Arabidopsis

Binqing Chen, Xie Dang, Wenting Bai, Min Liu et autres

Plant cells continuously experience mechanical stress resulting from the cell wall that bears internal turgor pressure. Cortical microtubules align with the predicted maximal tensile stress direction to guide cellulose biosynthesis and therefore results in cell wall reinforcement. We have previously identified Increased …

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A switchable Cas12a enabling CRISPR-based direct histone deacetylase activity detection

Wenyuan Kang, Lin Liu, Peihang Yu, Tianyi Zhang et autres

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Integration of electrochemical interface and cell-free synthetic biology for biosensing

Peihang Yu, Chunyang Lei, Zhou Nie

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An all-in-one telomerase assay based on CRISPR-Cas12a trans-cleavage while telomere synthesis

Peihang Yu, Tiantian Yang, Decai Zhang, Lulu Xu et autres

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Reactive oxygen species mediate conical cell shaping in Arabidopsis thaliana petals

Xie Dang, Peihang Yu, Yajun Li, Yanqiu Yang et autres

Plants have evolved diverse cell types with distinct sizes, shapes, and functions. For example, most flowering plants contain specialized petal conical epidermal cells that are thought to attract pollinators and influence light capture and reflectance, but the molecular mechanisms controlling conical cell …

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Spatio-temporal orientation of microtubules controls conical cell shape in Arabidopsis thaliana petals

Huibo Ren, Xie Dang, Xianzhi Cai, Peihang Yu et autres

The physiological functions of epidermal cells are largely determined by their diverse morphologies. Most flowering plants have special conical-shaped petal epidermal cells that are thought to influence light capture and reflectance, and provide pollinator grips, but the molecular mechanisms controlling conical cell …

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