Lili Ren

Abstract 4037: Pharmacological inhibition of eIF4A1 suppresses leukemogenesis via specifically rewiring amino acid biosynthesis

Xu Hannah Zhang, H Zhang, Lei Dong, Alexandra Huang et autres

Abstract Acute myeloid leukemia (AML) is an aggressive blood malignancy with a dismal 5-year survival rate below 30%. Dysregulation of mRNA translation is a hallmark and a driver of tumorigenesis, including leukemogenesis. However, the precise contributions of translation factors to AML pathogenesis …

us, cn (code pays fourni par la source)

Supplementary Data from The IGF2BP3–COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Figures

Supplementary Tables from The IGF2BP3–COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Tables

Arginine methylation-dependent METTL14-SMN interaction regulates RNA m6A homeostasis

Yi qin Zhang, Lei Shen, Lili Ren, Jiangbo Wei et autres

Abstract N6-methyladenosine (m 6 A) homeostasis is essential for development, and its dysregulation is linked to cancers and neurological disorders. However, the mechanisms regulating m 6 A remain unclear. Here, we identify the survival of motoneuron (SMN) protein as a novel interaction …

us, sg (code pays fourni par la source)

RTP4 restricts influenza A virus infection by targeting the viral NS1 protein

Xueying Lv, Tian Zheng, Xiaobo Lei, Lili Ren et autres

cn (code pays fourni par la source)

Supplementary Data from The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Figures

Supplementary Tables from The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Tables

Data from The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Abstract Many studies have provided valuable information about genomic and transcriptomic changes that occur in colorectal cancer (CRC). However, protein abundance cannot be reliably predicted by DNA alteration or mRNA expression, which can be partially attributed to post-transcriptional and/or translational regulation of …

Supplementary Data from The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Figures

Supplementary Tables from The IGF2BP3-COPS7B axis facilitates mRNA translation to drive colorectal cancer progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Tables

Supplementary Tables from The IGF2BP3–COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Supplementary Tables

Data from The IGF2BP3–COPS7B Axis Facilitates mRNA Translation to Drive Colorectal Cancer Progression

Jing Tang, Shuoshuo Wang, Mingjiao Weng, Qingyu Guo et autres

Abstract Many studies have provided valuable information about genomic and transcriptomic changes that occur in colorectal cancer. However, protein abundance cannot be reliably predicted by DNA alteration or mRNA expression, which can be partially attributed to posttranscriptional and/or translational regulation of gene …