Zhenning Tang

l-rhamnose suppresses triple-negative breast cancer via GSTM5-mediated ferroptosis

Shuangshuang Li, Qingyuan Liu, Yongzhao Zhu, Zhenning Tang

Triple-negative breast cancer lacks effective targeted therapies, necessitating novel treatment approaches.To evaluate the antitumor efficacy and molecular mechanisms of l -rhamnose in TNBC. We employed an integrated approach combining in vitro cell-based assays and in vivo xenograft models. TNBC cell lines (MDA-MB-231, …

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Interaction of canadine with thymidylate synthase mediated its promising anticancer activity on MCF-7 human breast cancer cells

Yuchen Wang, Chaolin Zhang, Hui Yu, Zhenning Tang et autres

In this study, the cytotoxic effects of canadine (xanthopuccine or tetrahydroberberine), a benzylisoquinoline alkaloid with a molecular formula of C 20 H 21 NO 4 , on the proliferation of Michigan Cancer Foundation-7 (MCF-7) human breast cancer cells and MCF-10 human normal …

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Global, regional, and national analyses of the burden among adult women of breast cancer attributable to diet high in red meat from 1990 to 2021: longitudinal observational study

Xiaoyun Ding, Zhenning Tang, Hang Ma

Background: The association between red meat consumption and breast cancer risk has been well established; however, it is crucial to understand the temporal trends, geographical variations, and socio-demographic factors that influence this risk among women aged 25-45. Consequently, this study seeks to …

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Hippocampus- and neocortex-specific deletion of Aeg-1 causes learning memory impairment and depression in mice

Ning Zhou, Panpan Wan, Xintong Li, Chunyang Yu et autres

Abstract Astrocyte elevated gene-1 (AEG-1) has been characterized as an oncogene promoting the progression of various tumors. The role of AEG-1 in neurological diseases was highlighted by recent researches. However, the physiological function of AEG-1 remains elusive. Our study aimed to investigate …

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d-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer

Zhenning Tang, Hanying Song, Shaojie Qin, Zengjian Tian et autres

Breast cancer patients often have a poor prognosis largely due to lack of effective targeted therapy. It is now well established that monosaccharide enhances growth retardation and chemotherapy sensitivity in tumor cells. We investigated whether D-arabinose has capability to restrict the proliferation …

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Analysis on status quo and related factors of delays in diagnosis and treatment of breast cancer in Ningxia Hui Autonomous Region

Yuchen Wang, Zhoulan Bai, Qingyuan Liu, Hui Yu et autres

This study aimed to explore factors contributing to the delays in the diagnosis and treatment of breast cancer (BC) in Ningxia Hui Autonomous Region. We conducted a cohort analysis of 1012 patients with BC diagnosed at the General Hospital of Ningxia Medical …

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Identification of Breast Cancer Immune-related Prognostic Characteristics in Tumor Microenvironment

Zhenning Tang, Ling Li, Xiao‐Ying Huang, Yinbing Zhao et autres

BACKGROUND: Accumulated evidence suggest that tumor microenvironment (TME) plays a crucial role in breast cancer (BRCA) progression and therapeutic effects. OBJECTIVE: This study aimed to characterize immune-related BRCA subtypes in TME, and identify genes with prognostic value. METHODS: RNA sequencing profiles with …

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Association of molecular subtypes and treatment with survival in invasive micropapillary breast cancer: an analysis of the Surveillance, Epidemiology, and End Results database

Zhenning Tang, Ling Li, Xiaoying Huang, Yinbing Zhao et autres

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[Application of carbon nanoparticle in neck Ⅵ lymph node dissection for papillary thyroid carcinoma].

Haoyan Fu, Zhengping Zhang, Zhenning Tang, QI-LUN LIU

Carbon nanoparticle injected as a lymph tracer in thyroid surgery is helpful, the characteristics of the parathyroid gland negative imaging can effectively decrease the rate of parathyroid gland injury.

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[Giant nodular goiter presented as a mass in chest wall: a case report].

Zhenning Tang, Qilun Liu, Zhiqiang Hu, Ligang Wu

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A rare presentation of a large goiter with papillary thyroid microcarcinoma as a chest wall mass: A case report

Zhenning Tang, QI-LUN LIU, Zhiqiang Hu, Ligang Wu

Nodular goiter affects numerous individuals worldwide. As the thyroid enlarges, it normally extends into the mediastinum as a result of its anatomical location under the investing layer of the deep cervical fascia. The present study reports the rare case of a 76-year-old …

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