Raj Bathula

Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial

Philip S. Nash, Hakim‐Moulay Dehbi, Norin Ahmed, Liz Arram et autres

BACKGROUND: Patients with chronic kidney disease (CKD) are at increased risk of ischemic stroke (IS) and intracerebral hemorrhage, so the safety and efficacy of early direct oral anticoagulant (DOAC) initiation in those with CKD are of clinical relevance. METHODS: OPTIMAS (Optimal Timing …

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Improving hyperacute stroke pathways at two specialist cardiothoracic centres (Royal Brompton Hospital and Harefield Hospital)

Jennie Han, Aneliya Takova, Dominic Lowcock, Hein Htet Zaw et autres

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Can Interventional Cardiologists Help Deliver the UK Mechanical Thrombectomy Interventional Programme for Patients with Acute Ischaemic Stroke? A Discussion Paper from the British Cardiovascular Interventional Society Stroke Thrombectomy Focus Group

Helen Routledge, Andrew Sharp, Jan Kovac, Mark Westwood et autres

There is a willingness among UK interventional cardiologists to contribute to provision of a 24/7 mechanical thrombectomy (MT) service for all suitable stroke patients if given the appropriate training. This highly effective intervention remains unavailable to the majority of patients who might …

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Stroke admissions: are we being paid enough? A cross-sectional study.

Amedra Basgaran, Knara Harut, Aravinth Sivagnanaratnam, Raj Bathula

Objectives: To investigate whether discharge summaries are accurately coding clinical details of patient admissions and to identify whether such differences lead to a loss of financial income for acute trusts. Design: A cross-sectional study of medical records, discharge summaries and financial outcomes. …

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Evaluating Rates of Recurrent Ischemic Stroke Among Young Adults With Embolic Stroke of Undetermined Source

Kanjana Perera, Danielle de Sá Boasquevisque, Rao Ps, Amanda Taylor et autres

Importance: Cryptogenic strokes constitute approximately 40% of ischemic strokes in young adults, and most meet criteria for the embolic stroke of undetermined source (ESUS). Two randomized clinical trials, NAVIGATE ESUS and RESPECT ESUS, showed a high rate of stroke recurrence in older …

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Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non-inferiority trial

Rustam Al‐Shahi Salman, Catriona Keerie, Jacqueline Stephen, Steff Lewis et autres

Impact of COVID-19 on Stroke Caseload in a Major Hyperacute Stroke Unit

Fionn Mag Uidhir, Raj Bathula, Aravinth Sivagnanaratnam, Mudhar Abdul-Saheb et autres

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Decreasing referrals to transient ischaemic attack clinics during the COVID-19 outbreak: results from a multicentre cross-sectional survey

Lucio D’Anna, Ambreen Sheikh, Raj Bathula, Salwa Elmamoun et autres

OBJECTIVE: The COVID-19 pandemic is having major implications for stroke care with a documented significant fall in hospital acute stroke admissions. We investigated whether COVID-19 has resulted in a decreased number of referrals to the transient ischaemic attack (TIA) clinics across the …

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Correction: Intensive Care Weaning (iCareWean) protocol on weaning from mechanical ventilation: a single-blinded multicentre randomised control trial comparing an open-loop decision support system and routine care, in the general intensive care unit

Lucio D’Anna, Ambreen Sheikh, Raj Bathula, Salwa Elmamoun et autres

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Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

H. Bart van der Worp, Malcolm Macleod, Philip M. Bath, Raj Bathula et autres

Abstract Introduction We assessed whether modest systemic cooling started within 6 hours of symptom onset improves functional outcome at three months in awake patients with acute ischaemic stroke. Patients and methods In this European randomised open-label clinical trial with blinded outcome assessment, …

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131 Acute stroke in ANCA associated vasculitis

Hasnain Hashim, Andrew Porter, Raj Bathula, Shahir Hamdulay

Background: Ischemic stroke is recognised in large vessel vasculitis, but is unusual in ANCA associated vascuiltis, often occurring with augmented cardiovascular risk factors and uncontrolled vascular inflammation. We describe three cases of ANCA associated vascuilitis presenting as acute stroke. Methods: Case 1: …

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Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Scott E. Kasner, Balakumar Swaminathan, Pablo M. Lavados, Mukul Sharma et autres

BACKGROUND: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa …

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