Keisuke Oka

Effectiveness of pharmacist-led management of candidemia in a tertiary care hospital without a full-time infectious disease specialist.

Teruhisa Kinoshita, Shoko Sahara, Atsuya Kondo, Yuki Kondo et autres

spp. distribution between the two groups. Compliance to the candidemia treatment bundle significantly improved in the post-antimicrobial stewardship team pharmacist intervention group (4.5% vs 39.6%); however, there was no difference between the two groups in 30-day mortality. The antimicrobial stewardship team pharmacist …

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A rare case of lateral cervical cyst infection associated with Bacillus subtilis subsp. natto

Nanako Nobuhiro, Hiroshi Morioka, Keisuke Oka, Yuto Fukuda et autres

Bacillus subtilis subsp. natto belongs to the Bacillaceae family and is used in "natto", a traditional Japanese food made from fermented soybeans. Recently, whole-genome sequencing has made it possible to distinguish B. subtilis from B. subtilis subsp. natto , and reports of …

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Evaluation of an in-house rapid antimicrobial susceptibility testing (RAST) using the direct disk-diffusion method for gram-negative bacilli from positive blood cultures in a Japanese tertiary hospital

Matt O’Hara, Mitsutaka Iguchi, Teruko Ohkura, Yukari Osada et autres

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Susceptibility to cefiderocol and other novel antibiotics against carbapenem-non-susceptible gram-negative bacilli

Teruko Ohkura, Rika Watarai, Masahiro Takekoshi, Matt O’Hara et autres

Cefiderocol (CFDC) is a novel siderophore cephalosporin with a unique cell entry feature and a high stability against a wide range of β-lactamases. We conducted antimicrobial susceptibility testing on 89 clinical isolates of carbapenem-non-susceptible gram-negative bacilli (CNS-GNB) strains detected at our hospital, …

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P-1293. Molecular and Phenotypic Characterization of ESBL-producing Enterobacter cloacae Complex Isolates Detected at a Single Japanese Hospital Over Seven Years

Tetsuya Yagi, Keisuke Oka

Abstract Background Enterobacter cloacae complex (ECC) possesses intrinsic chromosomal AmpC β-lactamase, often complicating the detection of extended-spectrum β-lactamase (ESBL) production. Although ECC has received less attention than other Enterobacterales in the context of ESBL production, the increasing prevalence of highly resistant ECC …

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Predictors of Myocardial Injury after Non-Cardiac Surgery (MINS): a retrospective single-center cohort study

K Okamoto, M Ishii, Kenjiro Ishigami, Keisuke Oka et autres

Abstract Background Myocardial injury after non-cardiac surgery (MINS) is a common and serious postoperative complication associated with increased morbidity and mortality. Various risk factors of MINS have been reported, including those in the revised cardiac risk index (RCRI), such as coronary artery …

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Prevalence of obstructive coronary artery disease in different calcification patterns on coronary computed tomography angiography

A Fujino, M Iguchi, M Abe, Keisuke Oka et autres

Abstract Background Although coronary computed tomography angiography (CCTA) is a valuable noninvasive modality for diagnosing coronary artery disease, coronary calcification can reduce its diagnostic accuracy due to artifacts. However, there are few studies investigating the association between the morphologic characteristics of coronary …

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Association between the presence or absence of symptoms and clinical outcomes in non-elderly patients with sustained atrial fibrillation without a history of heart failure: the Fushimi AF Registry

Y Ide, Keisuke Oka, K Okamoto, Y Yoshida et autres

Abstract Background We previously reported that asymptomatic patients with paroxysmal atrial fibrillation (AF) had a higher incidence of all-cause mortality than symptomatic patients, whereas this difference was not observed in those with sustained (persistent or permanent) AF (Esato M, et al. Chest. …

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Antimicrobial use in pediatric patients: a subgroup analysis of the 2020 point prevalence survey in Aichi, Japan

Hiroshi Morioka, Kenta Ito, Yusuke Koizumi, Masami Okudaira et autres

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A case of pyelonephritis and bacteremia caused by Candida glabrata in a patient on sodium glucose cotransporter 2 inhibitor, successfully treated with micafungin

Shoko Sahara, Teruhisa Kinoshita, Norio Takimoto, Keisuke Oka

BACKGROUND: Background factors for Candida spp. detection in urine include indwelling urinary catheters, diabetes mellitus, and a history of antimicrobial exposure; nevertheless, urinary tract infections caused by Candida spp. are usually rare. Fluconazole (FLCZ) is a preferable drug for the treatment of …

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Genomic insights into clinical non-O1/non-O139 Vibrio cholera e isolates in Japan

Yohei Kobayashi, Masato Suzuki, Shuntaro Umeda, Keisuke Oka et autres

ABSTRACT Non-O1/non-O139 Vibrio cholerae (NOVC) causes sporadic intestinal infections and systemic symptoms. Recently, global warming has led to an increase in NOVC infections; however, there have been no reports on the genomic analysis of clinical NOVC isolates in Japan, and the molecular …

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Antimicrobial use in Japanese hospitals: results from a point-prevalence survey in Aichi, 2020

Hiroshi Morioka, Yusuke Koizumi, Keisuke Oka, Masami Okudaira et autres

BACKGROUND: Comprehensive antimicrobial use (AMU) data are essential to promote effective antimicrobial stewardship. However, qualitative information on AMUs in Japanese hospitals is limited. AIM: To provide an overview of AMU for inpatients in Japanese hospitals. METHODS: A multi-centre point-prevalence survey was conducted …

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