Ching-Che Charng

Lateralized and bilateral sensory mechanisms independently regulate sociability and social preference in Drosophila

C C Yang, Ching-Hsin Chen, Ching-Che Charng, Kuan-Lin Feng et autres

Social behavior involves sociability—the drive to interact—and social preference—the choice of partners. Using FlySocialer , an automated system for tracking group interactions, we analyzed male Drosophila melanogaster and found highly individualized, non-random social behaviors. Compared to randomized controls, flies showed stable individual …

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High-resolution volumetric intravital imaging reveals asymmetric serotonin-dependent post-shock activity in the Drosophila brain

Heng Chang, Yueh‐Feng Wu, Ching-Che Charng, Kai-Chun Jhan et autres

Abstract Volumetric intravital imaging of adult Drosophila brains remains challenging due to optical scattering and speed limitations of conventional microscopy. Here, we present V-shape Bessel-beam light-sheet microscopy (vSPIM), an upright, high-speed platform achieving subcellular resolution across large, opaque volumes in vivo. Through …

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Reviewer #3 (Public review): Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

Chi-Lien Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

Reviewer #1 (Public review): Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

Chi-Lien Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

C C Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

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Reviewer #2 (Public review): Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

Chi-Lien Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

Author Response: Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

Chi-Lien Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

C C Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

In Drosophila, noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate nociceptor activity …

tw, in, us, jp, cn (code pays fourni par la source)

Individualized decision-making driven by long-term memory retrieval in Drosophila

Kuan-Lin Feng, Ming-Chin Wu, Ching-Che Charng, Chih-Yu Chou et autres

Decision-making is a dynamic process shaped by the accessibility of memory. The same information can lead to varying decisions both across individuals and within the same individual under different conditions. While memory retrieval plays a key role in guiding decision-making, its neural …

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Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

C C Yang, Chia-Wen Chen, Kuan-Lin Feng, Hsiao-Chien Peng et autres

Abstract In Drosophila , noxious heat is detected by peripheral nociceptors expressing transient receptor potential (TRP) channels, including Painless and TrpA1, and rapidly triggers escape behavior. Although peripheral transduction has been defined in detail, the central circuits and neuromodulatory mechanisms that translate …

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Hybrid neural networks in the mushroom body drive olfactory preference in Drosophila

Li-Shan Cheng, Ching-Che Charng, R Chen, Kuan-Lin Feng et autres

, olfactory encoding in the mushroom body (MB) involves thousands of Kenyon cells (KCs) processing inputs from hundreds of projection neurons (PNs). Recent data challenge the notion of random PN-to-KC connectivity, revealing preferential connections between food-related PNs and specific KCs. Our study …

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Unique Asymmetric Branching of Drosophila Neurons Optimizes Temporal Dendritic Computation

Ching-Che Charng, Harrison Hao-Yu Ku, Ann‐Shyn Chiang, Chung‐Chuan Lo

Neurons execute a versatile array of computations through a complex interplay of factors, including their morphology and synaptic architecture. Dendritic branching encodes upstream inputs into diverse spike patterns transmitted via downstream axons. While earlier studies highlighted the distinct morphologies and functions of …

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