Philippe Émy

Pénétrance de l’hyperplasie macronodulaire bilatérale des surrénales GIP-dépendante avec syndrome de Cushing chez les porteurs de mutations de KDM1A

F. Chasseloup, Lucie Cloix, M.L. Nunes, P. Galliot et autres

L’hyperplasie macronodulaire bilatérale des surrénales (HMBS) GIP-dépendante est une maladie génétique liée à une inactivation du gène KDM1A selon un modèle de gène suppresseur de tumeur. Notre objectif était d’évaluer la pénétrance et l’histoire naturelle de l’atteinte surrénalienne chez des porteurs de …

fr, it, be, gr, ca (code pays fourni par la source)

OR04-4 Loss of KDM1A in Bilateral Macronodular Adrenal Hyperplasia With GIP-Dependent Cushing's Syndrome and in Acromegaly With Paradoxical GH Response to Oral Glucose

Larbi Amazit, Mattia Barbot, Isabelle Beau, Jérôme Bouligand et autres

Abstract Context Primary bilateral macronodular adrenal hyperplasia (PBMAH) with glucose-dependent insulinotropic polypeptide (GIP)-dependent Cushing's syndrome is caused by ectopic expression of GIP receptor (GIPR) in the adrenal lesions. Such ectopic expression of GIPR was also reported in other endocrine neoplasm, notably in …

Loss of lysine demethylase KDM1A in GIP-dependent bilateral macronodular adrenal hyperplasia with Cushing's syndrome

Fanny Chasseloup, Isabelle Bourdeau, Antoine Tabarin, Daniela Regazzo et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

KDM1A inactivation causes hereditary food-dependent Cushing syndrome

Anna Vaczlavik, Lucas Bouys, Florian Violon, Giannone Gaetan et autres

fr, de, br, us (code pays fourni par la source)

LSD1/KDM1A Inactivation Causes Hereditary Food-Dependent Cushing’s Syndrome

Anna Vaczlavik, Lucas Bouys, Florian Violon, Giannone Gaetan et autres

fr, de, br, us (code pays fourni par la source)

Nouvelles règles relatives aux politiques de rémunération des dirigeants de sociétés cotées issues de l'ordonnance n° 2019-1234 et du décret n° 2019-1235 du 28 novembre 2019

Philippe Émy

International audience

Loi n° 2019-744 du 19 juillet 2019, de simplification, de clarification et d'actualisation du droit des sociétés : dispositions relatives aux opérations de restructuration entre sociétés commerciales

Philippe Émy

International audience

Cardiovascular complications in pituitary gigantism (results of an international study)

Liliya Rostomyan, Adrian Daly, Shah Nalini, A Naves Luciana et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients

Liliya Rostomyan, Adrian Daly, Patrick Pétrossians, E. Nachev et autres

Despite being a classical growth disorder, pituitary gigantism has not been studied previously in a standardized way. We performed a retrospective, multicenter, international study to characterize a large series of pituitary gigantism patients. We included 208 patients (163 males; 78.4%) with growth …

fr, be, bg, in, es, us, nz, nl, it, au, fi, ru, de, br (code pays fourni par la source)

Clinical Outcome, Hormonal Status, Gonadotrope Axis, and Testicular Function in 219 Adult Men Born With Classic 21-Hydroxylase Deficiency. A French National Survey

Claire Bouvattier, Laure Esterle, Peggy Renoult-Pierre, Aude Brac de la Perrière et autres

CONTEXT: Outcomes of congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency (21OHD) have been widely studied in children and women, but less so in men. OBJECTIVE: The objective was to analyze data from a network of metropolitan French teaching hospitals on the …

fr (code pays fourni par la source)

Hypopituitarism in pituitary gigantism (results of an international study)

Liliya Rostomyan, Adrian Daly, Nehal Shah, LA Naves et autres

be (code pays fourni par la source)

Adrenal rest tissue in gonads of patients with classical congenital adrenal hyperplasia: Multicenter study of 45 French male patients

P. Pierre, F Despert, François Tranquart, R. Coutant et autres

fr (code pays fourni par la source)