Christopher Dixon

Use of a rapid digital microfluidics-powered immunoassay for assessing measles and rubella infection and immunity in outbreak settings in the Democratic Republic of the Congo

Alaine Knipes, Aimee Summers, Alexandros A. Sklavounos, Julian Lamanna et autres

The Democratic Republic of the Congo (DRC) has a high measles incidence despite elimination efforts and has yet to introduce rubella vaccine. We evaluated the performance of a prototype rapid digital microfluidics powered (DMF) enzyme-linked immunoassay (ELISA) assessing measles and rubella infection, …

us, ca, République démocratique du Congo (code pays fourni par la source)

Portable sample processing for molecular assays: application to Zika virus diagnostics

Tanya Narahari, Joshua Dahmer, Alexandros A. Sklavounos, Tae-Hyeong Kim et autres

level from a 5 μL sample (equivalent to an RT-qPCR cycle threshold value of 32.0), demonstrating its potential as a sample processing platform for miniaturized diagnostic testing.

ca, br (code pays fourni par la source)

Can dynamic assessment predict growth in reading skills and risk status for reading difficulties?

Hannah M. Nash, Christopher Dixon, Paula J. Clarke, Anna Steenberg Gellert

In contrast to traditional ‘static’ tests,dynamic assessment (DA) focuses on the process rather than the product of learning by measuring response to teaching. As such, DA is better able to distinguish between underlying learning difficulties and lack of opportunity to learn, making …

gb (code pays fourni par la source)

Can a dynamic vocabulary learning task add to the prediction of growth in reading comprehension and the identification of children with reading comprehension difficulties?

Hannah M. Nash, Paula J. Clarke, Anna Steenberg Gellert, Anna Weighall et autres

current diagnostic and treatment systems?The multidimensional nature of reading development (2) » Prof.

gb (code pays fourni par la source)

Printed Digital Microfluidics for Diagnosis of Disease

Christopher Dixon

Digital Microfluidics (DMF) is a liquid handling technology comprising the manipulation of discrete droplets using electrostatic forces. Droplets are sandwiched in between a counter-electrode top plate and a bottom plate bearing an array of insulated driving electrodes. In this configuration, individual droplets, …

A Digital‐to‐Channel Microfluidic Interface via Inkjet Printing of Silver and UV Curing of Thiol–Enes

Gowtham Sathyanarayanan, Markus Haapala, Christopher Dixon, Aaron R. Wheeler et autres

Abstract Microfluidic sample manipulation is a key enabler in modern chemical biology research. Both discrete droplet‐based digital microfluidic (DMF) assays and continuous flow in‐channel assays are well established, each featuring unique advantages from the viewpoint of automation and parallelization. However, there are …

fi, ca (code pays fourni par la source)

Direct loading of blood for plasma separation and diagnostic assays on a digital microfluidic device

Christopher Dixon, Julian Lamanna, Aaron R. Wheeler

Finger-stick blood sampling is convenient for point of care diagnostics, but whole blood samples are problematic for many assays because of severe matrix effects associated with blood cells and cell debris. We introduce a new digital microfluidic (DMF) diagnostic platform with integrated …

ca (code pays fourni par la source)

A digital microfluidic system for serological immunoassays in remote settings

Alphonsus H. C. Ng, Ryan Fobel, Christian Fobel, Julian Lamanna et autres

= 135) compared with reference tests (measles IgG and rubella IgG ELISAs from Siemens Enzygnost) conducted in a centralized laboratory. These results demonstrate a potential role for this point-of-care system in global serological surveillance, particularly in remote areas with limited access to …

ca, Ouganda, Kenya, us, ch (code pays fourni par la source)

Language and Literacy Development in Children Learning English as an Additional Language: a Longitudinal Cohort and Vocabulary Intervention Study

Christopher Dixon

Children learning English as an Additional Language (EAL) are a growing but understudied population of learners in English primary schools. As EAL learners vary in their amount of exposure to English, they often begin formal education with relatively lower levels of English …

Printed Microfluidics

Christopher Dixon, Julian Lamanna, Aaron R. Wheeler

Microfluidics has become an important tool that is useful for a wide range of applications. A drawback for microfluidics is that many of the techniques that are commonly used to fabricate devices are not widely accessible, not scalable to high‐volume manufacturing processes, …

ca (code pays fourni par la source)

Pre-concentration by liquid intake by paper (P-CLIP): a new technique for large volumes and digital microfluidics

Darius G. Rackus, Richard P. S. de Campos, Calvin C. H. Chan, Maria M. Karcz et autres

Microfluidic platforms are an attractive option for incorporating complex fluid handling into low-cost and rapid diagnostic tests. A persistent challenge for microfluidics, however, is the mismatch in the "world-to-chip" interface - it is challenging to detect analytes present at low concentrations in …

ca (code pays fourni par la source)

An inkjet printed, roll-coated digital microfluidic device for inexpensive, miniaturized diagnostic assays

Christopher Dixon, Alphonsus H. C. Ng, Ryan Fobel, Mark B. Miltenburg et autres

for RV infection and immunity. We propose that this represents a breakthrough for DMF, lowering the costs to a level such that the new platforms will be an attractive alternative to LFAs for the diagnosis of infectious disease at the POC.

ca (code pays fourni par la source)