Jacqueline Leff

DEXTENZA versus Topical Steroid or Antihistamine Therapy for Treatment of Allergic Conjunctivitis

Shani S. Reich, Maria J Lopez, Jacqueline Leff, Jordan Herman

Purpose: To compare clinical outcomes and patient preference for the dexamethasone intracanalicular insert (DEX) versus topical loteprednol (LOT) or olopatadine (OLO) for the treatment of allergic conjunctivitis in a real-world model of allergen exposure. Methods: This was a prospective comparative trial. Adults …

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Using Simulated Patient Avatar and Monitor (SPA©M) to Advance Learner’s Knowledge of Pathophysiology and Pharmacology

David Colbourne, Matsuko Takeshige, Katrin Tamari, Harold Sirota et autres

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Distinct phases of adult microglia proliferation: a Myc-mediated early phase and a Tnfaip3-mediated late phase

Wulin Tan, Po‐Yi Paul Su, Jacqueline Leff, Xiang Gao et autres

Microgliosis is a hallmark of many neurological diseases, including Alzheimer's disease, stroke, seizure, traumatic brain and spinal cord injuries, and peripheral and optic nerve injuries. Recent studies have shown that the newly self-renewed microglia have specific neurological functions. However, the mechanism of …

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Cervicogenic dizziness alleviation after coblation discoplasty: a retrospective study

Liangliang He, Ru-jing Lai, Jacqueline Leff, Rong Yuan et autres

Objective Little is known about the therapeutic relationship between coblation discoplasty and cervicogenic dizziness (CGD). CGD can be caused by abnormal proprioceptive inputs from compressed nerve roots, intradiscal mechanoreceptors and nociceptors to the vestibulospinal nucleus in the degenerative cervical disc. The aim …

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Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

Xiaobing Yu, Hongju Liu, Katherine A. Hamel, Maelig G. Morvan et autres

Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG). Here we demonstrate a critical contribution of DRG macrophages, but not those at the …

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Rapid Isolation of Dorsal Root Ganglion Macrophages

Xiaobing Yu, Jacqueline Leff, Zhonghui Guan

There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral nerve injury. Peripheral monocytic cells, including macrophages, are known to respond to a tissue injury through phagocytosis, antigen …

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Rapid Isolation of Dorsal Root Ganglion Macrophages

Xiaobing Yu, Jacqueline Leff, Zhonghui Guan

There are growing interests to study the molecular and cellular interactions among immune cells and sensory neurons in the dorsal root ganglia after peripheral nerve injury. Peripheral monocytic cells, including macrophages, are known to respond to a tissue injury through phagocytosis, antigen …

us (code pays fourni par la source)