B. Maraghechi

Evaluation of QUASAR Insight Phantom for daily imaging QA of MRgRT linacs

Eli Grant, Jiayi Liu, Ronak Etemadpour, Chengyu Shi et autres

PURPOSE: Magnetic resonance imaging (MRI) and its importance in modern radiation therapy requires a standardized daily quality assurance (QA) procedure that is both comprehensive and efficient. Current imaging QA guidelines require a more inclusive analysis of imaging characteristics, as well as a …

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Determining the Ideal Uptake Time for Gadoxetate Disodium-Enhanced Liver Tumor Delineation on a 0.35 T MR-Linac

Edward Grant, A. Kassardjian, Chengyu Shi, Huisi Ai et autres

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Quantitative use of cone-beam computed tomography in proton therapy: challenges and opportunities

Hamid Ghaznavi, B. Maraghechi, Hailei Zhang, Tong Zhu et autres

The fundamental goal in radiation therapy (RT) is to simultaneously maximize tumor cell killing and healthy tissue sparing. Reducing uncertainty margins improves normal tissue sparing, but generally requires advanced techniques. Adaptive RT (ART) is a compelling technique that leverages daily imaging and …

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CT-Guided Online Adaptive Radiotherapy Delivered via Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) for a Bulky Thoracic and Abdominal Mass in Oligometastatic Renal Cell Carcinoma

Ari A Kassardjian, Colton Ladbury, B. Maraghechi, Chengyu Shi et autres

In the context of oligometastatic renal cell carcinoma (RCC), local treatment with stereotactic body radiotherapy (SBRT) may improve oncologic outcomes. However, the location and size can often pose a technical challenge in standard SBRT delivery, and the dose is potentially limited by …

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CT-Guided Online Adaptive Hypofractionated Radiotherapy for Primary Bladder Cancer: A Report of Two Cases

Ryan M. Davis, Colton Ladbury, Kevin Tsai, B. Maraghechi et autres

Trimodality treatment for bladder cancer, consisting of maximal transurethral resection of the tumor followed by concurrent chemoradiotherapy, is an attractive management option with curative and organ-sparing intent. However, such treatment can be associated with acute toxicities related to the large treatment margins …

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Use of Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy for Oligometastatic Lung Adenocarcinoma: Leveraging CT-Guided Online Adaptive Radiotherapy

Nicholas Eustace, Colton Ladbury, Yufei Liu, Arya Amini et autres

Management of oligometastatic non-small cell lung cancer (OM-NSCLC) has changed considerably in recent years, as these patients were found to have better survival with systemic therapy followed by consolidative radiation. Stereotactic body radiotherapy (SBRT), characterized by high doses of radiation delivered in …

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Dosimetric predictors of acute and late gastrointestinal toxicities in stereotactic online adaptive magnetic resonance-guided radiotherapy (SMART) for locally advanced pancreatic adenocarcinoma

Alden D'Souza, H.B. Stowe, Olga L. Green, Joshua P. Schiff et autres

BACKGROUND AND PURPOSE: A retrospective evaluation of dosimetric predictors and leveraged dose-volume data for gastrointestinal (GI) toxicities for locally-advanced pancreatic cancer (LAPC) treated with daily stereotactic MRI-guided online-adaptive radiotherapy (SMART). MATERIALS AND METHODS: 147 patients with LAPC were treated with SMART at …

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Dosimetric Predictors of Acute and Late Gastrointestinal Toxicities in Stereotactic Online Adaptive Magnetic Resonance-Guided Radiotherapy (Smart) for Locally Advanced Pancreatic Adenocarcinoma

H.B. Stowe, Olga L. Green, Joshua P. Schiff, Geoff Hugo et autres

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Initial clinical experience building a dual CT- and MR-guided adaptive radiotherapy program

Alex Price, Joshua P. Schiff, Eric Laugeman, B. Maraghechi et autres

Introduction: Our institution was the first in the world to clinically implement MR-guided adaptive radiotherapy (MRgART) in 2014. In 2021, we installed a CT-guided adaptive radiotherapy (CTgART) unit, becoming one of the first clinics in the world to build a dual-modality ART …

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MO-0884 knowledge-based adaptive QA using dosimetric indicators for stereotactic adaptive RT for pancreas

Alex Price, F. Forghani-Arani, B. Maraghechi, Luke Marut et autres

Knowledge-based adaptive planning quality assurance using dosimetric indicators for stereotactic adaptive radiotherapy for pancreatic cancer

Farnoush Forghani, John Ginn, Joshua P. Schiff, Tong Zhu et autres

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Noninvasive tissue temperature estimation using nonlinear ultrasound harmonics

B. Maraghechi, Michael C. Kolios, Jahangir Tavakkoli

Non-invasive tissue temperature estimation is important in thermal therapies for having an efficient treatment. A noninvasive ultrasonic technique for monitoring tissue temperature changes is proposed based on the changes in the harmonics of ultrasound backscatter as a function of temperature. The backscattered …

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