Ya‐Jane Lee

Evaluating the Adjuvant Therapeutic Effects of Probiotic Strains Lactococcus cremoris and Lacticaseibacillus paracasei on Canine Atopic Dermatitis and Their Impact on the Gut and Skin Microbiome

Hsiao-Wen Huang, Ting-Chen Yeh, Jui-Chun Hsieh, Ching‐Wen Tsai et autres

This study investigated the therapeutic potential of a novel probiotic combination consisting of Lactococcus cremoris subsp. cremoris MP01 and Lacticaseibacillus paracasei subsp. paracasei MP02, collectively referred to as LCP, in the treatment of canine atopic dermatitis (CAD). In a 60-day open-label, single-arm …

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Multi-omics analysis reveals the efficacy of two probiotic strains in managing feline chronic kidney disease through gut microbiome and host metabolome

Hsiao‐Wen Huang, Tzu-Chien Kuo, Ya‐Jane Lee, Ming‐Ju Chen

Gut dysbiosis has been implicated in the progression of chronic kidney disease (CKD), yet the functional alterations of the microbiome and their links to host metabolism in feline CKD pathophysiology remain unclear. Our previous findings suggested that Lactobacillus mix (Lm) may mitigate …

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P-434 Association of estrogen receptor alpha expression with endometrial receptivity and pregnancy outcomes

T H Lee, Ya‐Jane Lee, En‐Hui Cheng, C I Lee et autres

Abstract Study question Does estrogen receptor alpha (ERα) expression vary across different endometrial receptivity stages, and is it associated with age and pregnancy outcomes? Summary answer ERα expression significantly differs among Endometrial Receptivity Array (ERA)-defined stages and correlates with pregnancy outcomes but …

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Stem Cell Therapy as a Potentially Effective Treatment for End-Stage Kidney Failure in Cats

Ya‐Jane Lee, Eun Joo Kang, Jing Ju

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Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease

Chien-Hui Chen, Wei‐Li Hsu, Pei‐Shiue Tsai, Chun‐Fu Lai et autres

Introduction Hypoxia-inducible factors (HIF) regulate gene transcription, which aids hypoxia adaptation while promoting renal fibrosis. Non-transferrin-bound iron (NTBI) is a catalytic form of iron that can lead to oxidative damage. However, NTBI in cat biofluids has rarely been evaluated. Aims We assessed …

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631P Exploratory biomarker analysis in EGFR mutated NSCLC patients who treated with atezolizumab plus bevacizumab and chemotherapy from phase III ATTLAS trial

Hyung Jun Kim, Sehhoon Park, Taek Min Kim, J-Y. Han et autres

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RWD52 Factors Influencing Urate-Lowering Therapy Prescriptions in Gout Patients: A Retrospective National Cohort Study

Jiwon Jung, Ya‐Jane Lee, Hye‐Young Kang

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Depression and its impact on stroke risk and mortality in post-percutaneous coronary intervention patients: a nationwide retrospective cohort study

Ya‐Jane Lee, Dong Huey Cheon, Joon Hyeok Lee, Moon Soo Park et autres

Abstract Background/Introduction Cardiovascular disease (CVD) remains a leading cause of global mortality, with percutaneous coronary intervention (PCI) being a common therapeutic procedure for managing CVD. While depression is recognized as a risk factor for adverse cardiovascular outcomes post-PCI, its association with stroke …

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Evaluation of chronic stress status and quality of life in cats suffering from chronic kidney disease and suspected feline infectious peritonitis based on hair cortisol concentration analysis and a questionnaire

Chien-Hui Chen, Chao‐Chin Chang, Wei-Che Chen, Ya‐Jane Lee

Hair cortisol concentration (HCC) and a questionnaire were used as indicators of chronic stress status and quality of life (QoL), respectively, in cats. To date, there has been limited research on the simultaneous application of both indicators in unwell cats. Our aim …

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Evaluating the Adjuvant Therapeutic Effects of Probiotic Strains Lactococcus cremoris and Lacticaseibacillus paracasei on Canine Atopic Dermatitis and Their Impact on the Gut and Skin Microbiome

Hsiao‐Wen Huang, Ting-Chen Yeh, Jui-Chun Hsieh, Ching‐Wen Tsai et autres

Canine atopic dermatitis (CAD) is a common chronic allergic skin disease. In our previous study, we isolated two probiotic strains, Lactococcus cremoris subsp. cremoris MP01 and Lacticaseibacillus paracasei subsp. paracasei MP02, from Mongolian fermented milk. These strains demonstrated potential in alleviating symptoms …

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Urinary angiotensin-converting enzyme 2 and its activity in cats with chronic kidney disease

Tzu-Chien Kuo, Wei‐Li Hsu, Vin‐Cent Wu, Tong‐Rong Jan et autres

Introduction Angiotensin-converting enzyme 2 (ACE2) played an important role in the renin-angiotensin-aldosterone system (RAAS) and it was proved to be renoprotective in renal disease. Urinary angiotensin-converting enzyme 2 (uACE2) has been shown to reflect renal injury in human and experimental studies, but …

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Investigating the Efficacy of Kidney-Protective Lactobacillus Mixture-Containing Pet Treats in Feline Chronic Kidney Disease and Its Possible Mechanism

Ching‐Wen Tsai, Hsiao‐Wen Huang, Ya‐Jane Lee, Ming‐Ju Chen

mixture (Lm) was previously demonstrated to exert a renal-protective function in the CKD mice model. The efficacy of probiotics in pet foods is a relatively new area of study, and thus verifying the potential health benefits is necessary. This study evaluated the …

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