Isabel Martín‐Fuentes

Effects of high-intensity interval training with or without resistance training on Alzheimer’s disease brain signatures in individuals with coronary artery disease: the Heart-Brain randomized controlled trial

Javier Sanchez‐Martinez, Patricio Solis‐Urra, Ángel Toval, Andrea Coca‐Pulido et autres

Abstract Background Coronary artery disease (CAD) increases the risk of cognitive impairment, dementia, and brain structural alterations. This heart-brain connection suggests that exercise-induced cardiovascular responses may influence brain regions vulnerable to Alzheimer’s disease (AD), the most common cause of dementia. This study …

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Effect of a 24‐week resistance exercise intervention on cognitive function in cognitively normal older adults: The AGUEDA randomized controlled trial

Beatriz Fernandez‐Gamez, Patricio Solis‐Urra, Andrea Coca‐Pulido, Cristina Molina-Hidalgo et autres

INTRODUCTION The Active Gains in Brain Using Exercise During Aging (AGUEDA) trial examined the effects of a 24 week resistance exercise (RE) intervention on executive function (EF) and other cognitive domains in cognitively normal older adults. METHODS Ninety participants (mean age, 71.8 …

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Associations of cardiorespiratory fitness indicators with brain volumes and cognitive function in patients with coronary artery disease: findings from the Heart–Brain trial

Anna Carlén, Lucía Sánchez‐Aranda, Patricio Solis‐Urra, Andrea Coca‐Pulido et autres

AIM: Patients with coronary artery disease (CAD) are at risk of accelerated cognitive decline. We aimed to explore how different cardiorespiratory fitness (CRF) indicators associate with brain structure and cognitive function in these patients. METHODS: We studied 105 stable CAD patients (62.1±6.6 …

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Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Acute Exercise (flADex): Protocol for a Randomized Crossover Trial

Isabel Martín‐Fuentes, Beatriz Fernandez‐Gamez, Sol Vidal‐Almela, Alfredo Caro‐Rus et autres

INTRODUCTION: Alzheimer's disease (AD) is a leading cause of disability worldwide. Alterations in cerebral blood flow (CBF) and AD blood biomarkers are fundamental at early stages of AD. Exercise shows promise in delaying physiological changes, but its mechanisms for enhancing brain health …

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Reliability and Concurrent Validity of a Low-Cost Handgrip Dynamometer: The Camry

Lucía Sánchez‐Aranda, Javier Fernández-Ortega, Isabel Martín‐Fuentes, Ángel Toval et autres

IMPORTANCE: Handgrip testing is highly valid and reliable, but the high cost of dynamometers limits their use in some settings. A more affordable option, the Camry dynamometer, has recently been used in fitness surveillance; however, its reliability and validity compared with known …

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Real-Time HIIT Response in Patients with Coronary Artery Disease: A CERT-Based Report from the Heart-Brain Randomized Controlled Trial

Javier Fernández‐Ortega, Ángel Toval, Lucía Sánchez‐Aranda, Patricio Solis‐Urra et autres

Abstract Aims High-intensity interval training (HIIT) and resistance training (RT) are promising options for cardiac rehabilitation, yet exercise trials seldom report sufficient protocol details or participants’ response and experience in a standardised way. We therefore quantified and compared attendance rate, heart-rate–based compliance, …

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Association of 24 h-movement behaviors with cerebral and hippocampal amyloid beta levels and executive function in cognitively normal older adults: a compositional data analysis from the AGUEDA trial

Alessandro Sclafani, Jairo H. Migueles, Marcos Olvera‐Rojas, Patricio Solis‐Urra et autres

OBJECTIVES: This study investigated the associations between movement behaviors (physical activity, sedentary behavior, and sleep duration), global and hippocampal amyloid beta levels, and executive function in cognitively normal older adults. DESIGN: Cross-sectional analysis using data from the Active Gains in brain Using …

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Gait Variability Is Associated With Gray Matter Volumes Implicated in Cognitive Function: A Cross-Sectional Analysis From the AGUEDA Trial

Isabel Martín‐Fuentes, Patricio Solis‐Urra, Emilio J. Ruiz‐Malagón, Andrea Coca‐Pulido et autres

Abstract Background and Objectives Aging is associated with both gait impairments and cognitive decline; however, the relationship between specific gait variability parameters, gray matter volume (GMV), and cognitive function remains poorly understood. This study aims to examine the associations between gait variability …

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Resistance exercise for optimizing cognitive function during aging: the role of individual characteristics

Patricio Solis‐Urra, Beatriz Fernandez‐Gamez, Andrea Coca‐Pulido, Cristina Molina-Hidalgo et autres

Physical exercise has emerged as one of the leading non-pharmaceutical approaches to delay cognitive decline. However, the limited understanding of the mechanisms by which exercise impacts cognition and the poor description of exercise programs in late adulthood hinder the widespread use of …

Understanding Cerebral Blood Flow Dynamics for Alzheimer's Disease Prevention Through Acute Exercise (flADex) : Protocol for a Randomized Crossover Trial

Isabel Martín‐Fuentes, Beatriz Fernandez‐Gamez, Sol Vidal‐Almela, Alfredo Caro‐Rus et autres

Introduction Alzheimer's disease (AD) is a leading cause of disability worldwide. Alterations in cerebral blood flow (CBF) and AD blood biomarkers are fundamental at early stages of AD. Exercise shows promise in delaying physiological changes, but its mechanisms for enhancing brain health …

es, nl, us, se (code pays fourni par la source)

Understanding cerebral blood flow dynamics for Alzheimer’s disease prevention through acute exercise (flADex): Protocol for a randomized crossover trial

Isabel Martín‐Fuentes, Beatriz Fernandez‐Gamez, Sol Vidal‐Almela, Alfredo Caro‐Rus et autres

ABSTRACT INTRODUCTION Alzheimer’s disease (AD) is a leading cause of disability worldwide. Alterations in cerebral blood flow (CBF) and AD blood biomarkers are fundamental at early stages of AD. Exercise shows promise in delaying physiological changes, but its mechanisms for enhancing brain …

jp, cl, nl, us, se, es, fi (code pays fourni par la source)

Fitness, Gray Matter Volume, and Executive Function in Cognitively Normal Older Adults: Cross‐Sectional Findings From the AGUEDA Trial

Andrea Coca‐Pulido, Patricio Solis‐Urra, Beatriz Fernandez‐Gamez, Marcos Olvera‐Rojas et autres

The aim of the study is to investigate the association of cardiorespiratory fitness (CRF) and muscular strength indicators with gray matter volume (GMV) and to study whether fitness-related regions of GMV are associated to executive function (EF) in cognitively normal older adults. …

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