Dong‐Chun Hong

Subcutaneous injection of semaglutide causes increased muscle uptake of 18F-FDG and reduces the imaging quality of PET/CT: a case report

Dong‐Chun Hong, Liyuan Le, Weipeng Chen, Wen Long et autres

Semaglutide, a glucagon-like peptide-1 receptor agonist widely used in diabetes management, has not been previously reported to interfere with PET/CT imaging. This case highlights a novel observation regarding same-day subcutaneous semaglutide injection leading to increased muscular 18 F-FDG uptake, which compromises lesion …

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Chimeric Glycoprotein Nanoparticles Elicit Robust Neutralizing Antibodies Against Epstein–Barr Virus (Adv. Mater. 7/2026)

Cong Sun, Chu Xie, Xin‐Yan Fang, Dong‐Chun Hong et autres

EBV Vaccine Cong Sun, Zheng Liu, Mu-Sheng Zeng, and colleagues design a chimeric nanoparticle displaying multiple EBV glycoproteins in virion-mimicry pattern. It induces potent neutralizing antibodies against Epstein-Barr virus. This vaccine offers a new strategy to comprise multiple antigens upon nanoparticle to …

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Supplementary Table S1 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

Clinical characteristics of patients in RIS group and SARC group as a whole, or for WES, or for mRNA- seq.

Supplementary Table S2 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

Differentially expressed genes (DEG), possible fusion genes and alternative splicing events, and the anti-tumor immunity scores and proliferation module scores of each sample.

Supplementary Figure S3 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

Comparison between RIS group and SARC group in mRNA-seq and WES data.(A) Expression levels of IDO and CTLA-4 in the RIS group and SARC group in mRNA-seq.(B) The anti-tumor immunity score and the proliferation module score of the RIFS group and the …

Supplementary Figure S1 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

The flowchart showing patient screening and identification, and analysis steps for mRNA-seq and WES data. FS: fibrosarcoma; OS: osteosarcoma.

Supplementary Figure S4 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

The landscape of copy number variants and results for blood detection.༈A༉Top genes in copy number changes in RIS and SARC groups filtered by COSMIC gene list.༈B༉Top genes in copy number changes in RIFS and FS subtypes.༈C༉Top genes in copy number changes in …

Supplementary Table S3 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

Clinical characteristics of patients treated with chemotherapy alone and chemotherapy plus anti-PD-1 antibody in RIS group.

Supplementary Table S4 from Genomic Profiling of Radiation-Induced Sarcomas Reveals the Immunologic Characteristics and Its Response to Immune Checkpoint Blockade

Dong‐Chun Hong, Jing Yang, Cong Sun, Yuan-Tao Liu et autres

Treatment-related adverse events of 30 RIS patients treated with chemotherapy plus anti-PD-1 antibody.

Chimeric Glycoprotein Nanoparticles Elicit Robust Neutralizing Antibodies Against Epstein–Barr Virus

Cong Sun, Chu Xie, Xin‐Yan Fang, Dong‐Chun Hong et autres

Epstein‒Barr virus (EBV) is a ubiquitous gammaherpesvirus linked to a broad spectrum of malignancies and autoimmune diseases with no approved therapeutic drugs or vaccines. EBV infection relies on the viral glycoproteins gB and gHgL, which, together, function as the fusion apparatus, mediating …

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Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma

Jing Yang, Xiuxia Lu, Qiyan Cai, Mengmeng Liu et autres

BACKGROUND: Soft tissue sarcoma (STS) is a rare, heterogeneous malignancy with limited treatment options for metastatic disease. Despite advances in immunotherapy, including PD-1 inhibitors, clinical outcomes remain suboptimal, highlighting the need for novel biomarkers and therapeutic strategies. This study investigated the role …

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A phase II, multicenter trial of the combination of chidamide and toripalimab in patients with advanced soft tissue sarcoma: Efficacy updates.

Xing Zhang, Ruiqing Peng, Peng Zhang, Wenhua Zhan et autres

11560 Background: Chidamide is an oral subtype-selective histone deacetylase (HDAC) inhibitor which is effective on the patients with hematological tumors and could be hoped to enhance the efficacy of checkpoint blockade therapies and regulate the host immune response. Here, we report the …

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