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Profil bibliographique

Pascal Haffter

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

80Publications signalées
15003Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Developmental Biology and Gene RegulationZebrafish Biomedical Research ApplicationsCongenital heart defects researchNuclear physics research studiesRNA and protein synthesis mechanisms

Les publications récentes

Accès ouvert 2008 article OpenAlex

Leukocyte Tyrosine Kinase Functions in Pigment Cell Development

Susana S. Lopes, Xueyan Yang, Jeanette Müller, Thomas J. Carney et autres

A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells (NCCs) are multipotent, yet the mechanisms driving specific fate choices remain incompletely understood. Sox10 is required for specification of neural cells and melanocytes from NCCs. Like …

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175 citations PLoS Genetics
Accès ouvert 2004 preprint OpenAlex

iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo

Christian M. Wolff, Sudipto Roy, Katharine E. Lewis, Heike E. Schauerte et autres

Signaling by lipid-modified secreted glycoproteins of the Hedgehog family play fundamental roles during pattern formation in animal development and in humans; dysfunction of Hedgehog pathway components is frequently associated with a variety of congenital abnormalities and cancer. Transcriptional regulation of Hedgehog target …

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114 citations Genes & Development
Accès ouvert 2003 article OpenAlex

The zebrafish van gogh mutation disrupts tbx1 , which is involved in the DiGeorge deletion syndrome in humans

Tatjana Piotrowski, Dae-gwon Ahn, Thomas Friedrich Schilling, Sreelaja Nair et autres

The van gogh (vgo) mutant in zebrafish is characterized by defects in the ear, pharyngeal arches and associated structures such as the thymus. We show that vgo is caused by a mutation in tbx1, a member of the large family of T-box …

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215 citations Development
2002 article OpenAlex

A zebrafishsox9gene required for cartilage morphogenesis

Yi‐Lin Yan, Craig T. Miller, Robert M. Nissen, Amy Singer et autres

The molecular genetic mechanisms of cartilage construction are incompletely understood. Zebrafish embryos homozygous for jellyfish (jef) mutations show craniofacial defects and lack cartilage elements of the neurocranium, pharyngeal arches, and pectoral girdle similar to humans with campomelic dysplasia. We show that two …

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307 citations Development
2001 article OpenAlex

Zebrafishcolourlessencodessox10and specifies non-ectomesenchymal neural crest fates

Kirsten A. Dutton, Angela Pauliny, Susana S. Lopes, Stone Elworthy et autres

Waardenburg-Shah syndrome combines the reduced enteric nervous system characteristic of Hirschsprung's disease with reduced pigment cell number, although the cell biological basis of the disease is unclear. We have analysed a zebrafish Waardenburg-Shah syndrome model. We show that the colourless gene encodes …

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530 citations Development
Accès ouvert 2001 article OpenAlex

Genetic steps to organ laterality in zebrafish

Jau‐Nian Chen, Frauke van Bebber, Allan M. Goldstein, Fabrizio C. Serluca et autres

All internal organs are asymmetric along the left-right axis. Here we report a genetic screen to discover mutations which perturb organ laterality. Our particular focus is upon whether, and how, organs are linked to each other as they achieve their laterally asymmetric …

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45 citations Comparative and Functional Genomics

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