Nancy C. Buchheimer

Long-term disability after lacunar stroke

Mandip S. Dhamoon, Leslie A. McClure, Carole L. White, Kamakshi Lakshminarayan et autres

OBJECTIVES: To determine whether vascular and demographic factors predict worsening disability up to 8 years after lacunar stroke. METHODS: SPS3 (Secondary Prevention of Small Subcortical Strokes) was a clinical trial in lacunar stroke patients with annual assessment of disability using the Older …

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C-Reactive Protein as a Prognostic Marker After Lacunar Stroke

Mitchell S.V. Elkind, Jorge M. Luna, Leslie A. McClure, Yu Zhang et autres

BACKGROUND AND PURPOSE: Inflammatory biomarkers predict incident and recurrent cardiac events, but their relationship to stroke prognosis is uncertain. We hypothesized that high-sensitivity C-reactive protein (hsCRP) predicts recurrent ischemic stroke after recent lacunar stroke. METHODS: Levels of Inflammatory Markers in the Treatment …

us, ec, cl, cn, in, ca, gb, jp, de, mx, es, nl (code pays fourni par la source)

A MEG investigation of somatosensory processing in the rhesus monkey

Tony W. Wilson, Dwayne W. Godwin, Paul W. Czoty, Michael A. Nader et autres

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PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys

Michael A. Nader, Drake Morgan, H. Donald Gage, Susan H. Nader et autres

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Behavioral Depression and Positron Emission Tomography–Determined Serotonin 1A Receptor Binding Potential in Cynomolgus Monkeys

Carol A. Shively, David P. Friedman, H. Donald Gage, Michael C. Bounds et autres

CONTEXT: Current animal models of depression are inadequate to further our understanding of depression. New models that allow for analysis of cognitive function and sex differences are needed. OBJECTIVE: To characterize serotonin 1A (5-HT(1A)) receptor binding potential (BP) and its relationship with …

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N‐[18F]4′‐fluorobenzylpiperidin‐4yl‐(2‐fluorophenyl) acetamide ([18F]FBFPA): A potential fluorine‐18 labeled PET radiotracer for imaging sigma‐1 receptors in the CNS

Robert H. Mach, H. Donald Gage, Nancy C. Buchheimer, Yun‐Sheng Huang et autres

A series of brain uptake studies and PET imaging studies were conducted with the sigma(1) selective imaging agent, [(18)F]FBFPA. The results of the study indicate that this radiotracer readily crosses the blood-brain barrier and labels sigma(1) receptors in vivo. In vivo blocking …

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Neuroimaging of Rodent and Primate Models of Alcoholism: Initial Reports From the Integrative Neuroscience Initiative on Alcoholism

Edith V. Sullivan, Helen J.K. Sable, Wendy N. Strother, David P. Friedman et autres

Neuroimaging of animal models of alcoholism offers a unique path for translational research to the human condition. Animal models permit manipulation of variables that are uncontrollable in clinical, human investigation. This symposium, which took place at the annual meeting of the Research …

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Evaluation of the Quantitative Capability of a High-Resolution Positron Emission Tomography Scanner for Small Animal Imaging

Frederic H. Fahey, H. Donald Gage, Nancy C. Buchheimer, Holly C. Smith et autres

OBJECTIVE: The quantitative capability of a positron emission tomography scanner for small animal imaging was evaluated in this study. METHODS: The microPET P4 (Concorde Microsystems, Knoxville, TN) scanner's capability for dynamic imaging and corrections for radioactive decay, dead time, and attenuation were …

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Neurofunctional imaging of the pancreas utilizing the cholinergic PET radioligand [ 18 F]4-fluorobenzyltrozamicol

Paige B. Clark, H. Donald Gage, Clive Brown-Proctor, Nancy C. Buchheimer et autres

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Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration

Drake Morgan, Kathleen A. Grant, H. Donald Gage, Robert H. Mach et autres

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[18F]N-4′-Fluorobenzyl-4-(3-bromophenyl) acetamide for imaging the sigma receptor status of tumors: comparison with [18F]FDG and [125I]IUDR

Robert H. Mach, Yun‐Sheng Huang, Nancy C. Buchheimer, R. Kuhner et autres

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