Umberto Ricardi

Outcomes and adverse events of postoperative stereotactic interventional radiotherapy/brachytherapy for brain metastases: a systematic review

Mateusz Bilski, Federico Mastroleo, Izabela Baranowska, Katarzyna Konat-Bąska et autres

Postoperative radiotherapy is commonly used after resection of brain metastases, but durable local control with a low rate of adverse events (AEs) remains challenging. This systematic review summarizes outcomes and AEs of postoperative stereotactic interventional radiotherapy (S-IRT; brachytherapy) for resected brain metastases. …

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Metabolic Outcome and CV Risk in Breast Cancer Patients

Francesco Felicetti, Gloria Mittica, Chiara Cavallin, Ester Campus et autres

Breast cancer [BC] is the most diagnosed cancer among women worldwide. Thanks to advancements in early detection, systemic therapies, and supportive care, survival rates have significantly improved. As more patients survive BC, cardiovascular disease [CVD] has emerged as a leading cause of …

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Bone metastases in salivary gland cancer: a retrospective analysis and review of the literature

Fabrizio Ferretti, Paolo Garzino Demo, Caterina Chiara Bianchi, Carlo Strada et autres

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ESTRO clinical practice guideline on high-dose thoracic reirradiation for non-small cell lung cancer

Nicolaus Andratschke, Jonas Willmann, Edy Ippolito, Carlo Greco et autres

PURPOSE: High-dose thoracic reirradiation is increasingly used in clinical practice for patients with non-small cell lung cancer (NSCLC) in a variety of clinical scenarios ranging from locoregional recurrence to selected metastatic settings. The treatment goals of thoracic reirradiation include durable local control, …

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Bridging evidence and practice: international multidisciplinary consensus on non-metastatic NSCLC

May‐Lucie Meyer, Solange PETERS, Hossein BORGHAEI, Tina CASCONE et autres

BACKGROUND: The management of non-metastatic non-small-cell lung cancer (NSCLC) has become increasingly complex with the integration of multimodality strategies and biomarker-driven approaches. Several clinically relevant areas remain insufficiently defined by current evidence and international guidelines. We conducted an international multidisciplinary consensus to …

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Local control in oligometastatic cancer patients following metastasis-directed stereotactic ablative radiotherapy: An interim analysis of ESTRO EORTC E2-RADIatE OligoCare cohort

Ines Joye, Umberto Ricardi, Marta Scorsetti, Filippo Alongi et autres

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Continuous positive airway pressure as an alternative to deep-inspiration breath holding for mediastinal lymphoma radiotherapy

Mario Levis, Paolo Solidoro, F.R. Giglioli, E. Gallio et autres

PURPOSE: This study explored Continuous Positive Airway Pressure (CPAP) as an alternative to breath-holding (DIBH) techniques by comparing it with free-breathing (FB) in mediastinal lymphoma patients treated with optimized volumetric arc therapy (VMAT). METHODS: Patients underwent computed tomography (CT) simulation in both …

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High-dose-rate vaginal brachytherapy for treatment of recurrent high-grade vaginal intraepithelial neoplasia

Jacopo Di Muzio, Niccolò Gallio, Valeria Chiofalo, Mario Preti et autres

PURPOSE: High-grade vaginal intraepithelial neoplasia (HG VaIN) is a rare preinvasive lesion characterized by a high risk of recurrence. Management strategies encompass both surgical excision, ablative procedures, and topical treatments. Brachytherapy provides a less invasive option, particularly for recurrent HG VaIN cases …

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365P Global patterns and future burden of lung cancer: Worldwide incidence and mortality in 2022 with projections to 2050

B. Donelian, N. Botelho Libonati, Vanessa Freitas Bratti, J. Willmann et autres

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401eP Patterns of lung cancer incidence and mortality in Europe: Age- and sex-stratified epidemiology and long-term projections

N. Botelho Libonati, B. Donelian, Julie‐Ann Francis, V. Zhang et autres

Lung cancer continues to impose the greatest mortality burden of any malignancy in Europe, reflecting historical tobacco exposure and persistent gaps in prevention and early detection. Contemporary, disaggregated estimates of disease burden and forward-looking projections are essential to guide evidence-based cancer control …

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Low-Dose Radiotherapy for Primary Cutaneous Indolent B-Cell Lymphomas: a Multicenter Retrospective Study

Emanuele Alì, Gabriele Simontacchi, Mario Levis, Silvia Gambara et autres

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ESMO-ESTRO consensus statements on the safety of combining radiotherapy with CDK4/6, HER2, PARP, or mTOR inhibitors

Evert S.M. van Aken, Ajeet Kumar Gandhi, Séan M. O’Cathail, Gerben Borst et autres

BACKGROUND: While combining radiotherapy (RT) with targeted agents or immunotherapy may improve outcomes, it may also increase toxicity. High-quality toxicity data and multidisciplinary, evidence-based guidelines on the combination of these treatment modalities are scarce. DESIGN: The European Society for Medical Oncology (ESMO) …

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