Mariusz R. Wiȩckowski

Introducing OBEClust: A Pan‐European Initiative to Harmonize Obesity Prevention Research and Strengthen Translation Into Policy

Maria Kafyra, PELIN ALPAY, Anabela Marisa Azul, Fernando Fernández‐Aranda et autres

Obesity remains one of the most pressing public health challenges in Europe, with substantial health, social, and economic consequences. Despite extensive research and numerous national strategies, obesity prevention efforts remain fragmented across countries, limiting comparability, scalability, and policy impact. The present description …

gr, pt, es, de, nl, gb, ch, pl, at, fr, lu, no (code pays fourni par la source)

Correction: Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and Imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

pl (code pays fourni par la source)

Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Abstract Background Alterations in cancer cell metabolism have recently gained considerable attention as a possible cause of adaptation and resistance to therapy. However, the underlying molecular mechanisms, particularly in leukemia resistance occurring in the bone marrow microenvironment, remain unclear. Here, we explore …

pl (code pays fourni par la source)

Additional file 1 of Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Supplementary Material 1.

pl (code pays fourni par la source)

Additional file 2 of Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Supplementary Material 2.

pl (code pays fourni par la source)

Additional file 2 of Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Supplementary Material 2.

pl (code pays fourni par la source)

Additional file 1 of Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Supplementary Material 1.

pl (code pays fourni par la source)

Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

Abstract Background Alterations in cancer cell metabolism have recently gained considerable attention as a possible cause of adaptation and resistance to therapy. However, the underlying molecular mechanisms, particularly in leukemia resistance occurring in the bone marrow microenvironment, remain unclear. Here, we explore …

pl (code pays fourni par la source)

Autophagy inhibition potentiates anti-cancer activity of Sunitinib in kidney cancer cells

Mariusz R. Wiȩckowski

This dataset corresponds to the article titled "Autophagy inhibition potentiates anti-cancer activity of Sunitinib in kidney cancer cells". It comprises the source data used for creating figures. Further information related to this dataset can be found in the correspondingly titled article. Mariusz …

Autophagy-related proteomics reveals lysosomal alterations linked to C19orf12 mutations and candidate biomarkers in MPAN patients' fibroblasts

B. Pakuła, Agata Wydrych, Magdalena Lebiedzinska-Arciszewska, Patrycja Jakubek et autres

Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) is the third most common genetically-defined subtype of Neurodegeneration with Brain Iron Accumulation (NBIA), a group of rare, clinically heterogeneous disorders. The MPAN pathomechanism, including the link between C19orf12 mutations, iron accumulation, and metabolic alterations, is still …

pl, it, nl (code pays fourni par la source)

Stroma-driven horizontal transfer of TCA-related proteins mediates metabolic plasticity and imatinib resistance in chronic myeloid leukemia

Piotr Chrościcki, Nikodem Kasak, Dorota Dymkowska, Laura Turos-Korgul et autres

BACKGROUND: Alterations in cancer cell metabolism have recently gained considerable attention as a possible cause of adaptation and resistance to therapy. However, the underlying molecular mechanisms, particularly in leukemia resistance occurring in the bone marrow microenvironment, remain unclear. Here, we explore the …

pl (code pays fourni par la source)

Distinct Neurodegenerative Pathways in Two NBIA Subtypes: Inflammatory Activation in C19orf12 but Not in PANK2 Mutation Carriers

Marta Skowrońska, Agnieszka Cudna, Barbara Pakuła, Magdalena Lebiedzińska et autres

BACKGROUND: Biomarker analysis in neurodegeneration with brain iron accumulation (NBIA) can offer valuable insights into the disease's pathology and natural history. METHODS: mutations causing pantothenate kinase-associated neurodegeneration (PKAN), and 30 age- and gender-matched controls were studied. Serum levels of MMP-9, S100B, ICAM-1, …

pl (code pays fourni par la source)