M Feldmann

Wann und wie können Anfallssuppressiva bei Epilepsie abgesetzt werden?

M Feldmann, Markus Weih

Absetzen anfallssuppressiver Medikamente bei Patient*innen mit Epilepsie

M Feldmann, Luise Graf, Thea Hüsing, Jakob Immanuel Dörrfuß et autres

BACKGROUND: Approximately two thirds of patients with epilepsy become seizure-free with antiseizure medication (ASM). A central question is whether and when ASM can be discontinued. OBJECTIVE: To present an overview of the current knowledge about risks and benefits of discontinuation of ASM. …

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Risk of Seizure Recurrence Due to Autoimmune Encephalitis With NMDAR, LGI1, CASPR2, and GABA B R Antibodies

Anna Rada, Anne Hagemann, Charlotte Aaberg Poulsen, Tobias R. Baumgartner et autres

BACKGROUND AND OBJECTIVES: R). We hypothesized that after a seizure-free period of 3 months, patients with AIE have a seizure recurrence risk of <20% during the subsequent 12 months. This would render them eligible for noncommercial driving according to driving regulations in …

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Tolerability of tariquidar – A third generation P-gp inhibitor as add-on medication to antiseizure medications in drug-resistant epilepsy

M Feldmann, Oliver Langer, Martin Bauer, Marie-Claude Asselin et autres

PURPOSE: P-glycoprotein (P-gp) has been hypothesized to be involved in drug-resistance of epilepsy by actively extruding antiseizure medications (ASMs) from the brain. The P-gp inhibitor tariquidar (TQD) has been shown to effectively inhibit P-gp at the human blood-brain barrier, improving brain entry …

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Epilepsie und Schwangerschaft

Verena Gaus, M Feldmann, Bettina Schmitz

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Elevated endothelin-1 levels as risk factor for an impaired ocular blood flow measured by OCT-A in glaucoma

Claudia Lommatzsch, Kai Rothaus, Lasse Schopmeyer, M Feldmann et autres

The purpose of this study was to ascertain whether a correlation exists between glaucoma-associated alteration of ocular vascular haemodynamics and endothelin-1 (ET-1) levels exist. Eyes of patients with cataract (n = 30) or glaucoma (n = 68) were examined with optical coherence …

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Bildgebung in der prächirurgischen Epilepsiediagnostik

M Feldmann, Bernd J. Vorderwülbecke, Mirja Steinbrenner

While two thirds of patients with epilepsy become seizure-free with antiseizure medications, 30% remain drug-resistant. In drug-resistant focal epilepsy, epilepsy surgery offers an approximately 65% chance of becoming seizure-free; however, for a successful outcome of surgery a seizure focus must be precisely …

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Long-term seizure outcome and antiseizure medication use in autoimmune encephalitis

M Feldmann, Harald Prüß, Martin Holtkamp

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PET in Epilepsy

Matthias J. Koepp, Marian Galovic, M Feldmann

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Biomarkers of Drug Response and Pharmacoresistance to Epilepsy

Britta Wandschneider, M Feldmann, Matthias J. Koepp

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PET und SPECT

M Feldmann, Martin Holtkamp, Robert Pichler, Tim J. von Oertzen

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Inter-ictal [O-15]H2O/PET differentiates between drug-resistant and seizure-free mesial temporal lobe epilepsy patients

Jake Ryan, M Feldmann, Matthew C. Walker, Vryonis Charalambous et autres

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