Crista Liesting

2D-echocardiography vs cardiac MRI strain: a prospective cohort study in patients with HER2-positive breast cancer undergoing trastuzumab

Nathalie I. Bouwer, Crista Liesting, Marcel J.M. Kofflard, Jasper J. Brugts et autres

BACKGROUND: We aimed to study the predictive value of early two-dimensional echocardiography (2DE) speckle tracking (ST) for left ventricular ejection fraction (LVEF) changes during trastuzumab treatment for HER2-positive breast cancer. METHODS: HER2-positive breast cancer patients receiving trastuzumab, with or without anthracycline, underwent …

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2D-echocardiography vs cardiac MRI strain using deep learning: a prospective cohort study in patients with HER2-positive breast cancer undergoing trastuzumab

NI Bouwer, Crista Liesting, M.J.M. Kofflard, JJ Brugts et autres

Abstract Funding Acknowledgements Type of funding sources: Private hospital(s). Main funding source(s): Promotiefonds Albert Schweitzer Hospital Background Subclinical cardiotoxicity due to trastuzumab could be recognized by repeated measurements of global longitudinal/radial strain (GLS/GRS) which could be performed with cardiac magnetic resonance (CMR) …

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ONCOR: design of the Dutch cardio-oncology registry

Janine A. M. Kamphuis, Marijke Linschoten, Maarten J. Cramer, F. Alsemgeest et autres

BACKGROUND: The relative new subspecialty 'cardio-oncology' was established to meet the growing demand for an interdisciplinary approach to the management of cancer therapy-related cardiovascular adverse events. In recent years, specialised cardio-oncology services have been implemented worldwide, which all strive to improve the …

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Cardiac monitoring in HER2-positive patients on trastuzumab treatment: A review and implications for clinical practice

Nathalie I. Bouwer, Agnes Jager, Crista Liesting, Marcel J.M. Kofflard et autres

Trastuzumab prolongs progression-free and overall survival in patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer. However, trastuzumab treatment is hampered by cardiotoxicity, defined as a left ventricular ejection fraction (LVEF) decline with a reported incidence ranging from 3 …

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NT-proBNP correlates with LVEF decline in HER2-positive breast cancer patients treated with trastuzumab

Nathalie I. Bouwer, Crista Liesting, Marcel J.M. Kofflard, Sylvia M. Sprangers-van Campen et autres

Early identification of cardiac dysfunction by non-invasive imaging in HER2-positive breast cancer patients treated with trastuzumab is challenging. In particular multigated acquisition (MUGA) scan, which is most widely used, is unable to detect subclinical cardiac changes. The use of N-terminal pro-brain natriuretic …

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Serial 18 F-fluorodeoxyglucose positron emission tomography/CT angiography in transcatheter-implanted aortic valve endocarditis

Laurens E. Swart, Asbjørn M. Scholtens, Crista Liesting, Nicolas M. Van Mieghem et autres

A 75-year-old woman was referred to our centre for suspicion of endocarditis. Six months earlier, she had undergone an uncomplicated transcatheter aortic valve implantation (TAVI; Medtronic CoreValve Evolut R). For several days prior to admission, she had been experiencing symptoms of drowsiness, …

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Obstructive cardiac tumour perfused by large vascular network from right coronary artery

Jasper J. Brugts, Crista Liesting, Leon van Woerkens, Marcel J.M. Kofflard

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Acute coronary syndrome in a patient with a single coronary artery arising from the right sinus of Valsalva

Crista Liesting

Coronary artery anomalies are usually encountered as coincidental findings during coronary angiography or at autopsy. Life threatening symptoms, such as arrhythmias, syncope, myocardial infarction, or sudden death, can occur in up to 20% of patients. However, the majority of anomalies (80%) are …

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Right-to-Left Atrial Shunting with Normal Intracardiac Pressures following Cardiac Surgery: Pathophysiology and Management

Jasper J. Brugts, Crista Liesting, Marcel J.M. Kofflard, Ewout J. van den Bos

We present a case of acute respiratory insufficiency with right-to-left atrial shunting under normal intracardiac pressures discovered several days after aortic surgery for aortic dissection. We discuss the possible mechanisms and management of right-to-left atrial shunting through an atrial septum defect with …

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Answer to the rhythm puzzle

Crista Liesting, Marcel J.M. Kofflard

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A simple broad complex tachycardia?

Crista Liesting, Marcel J.M. Kofflard

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Vroege detectie van cardiotoxiciteit bij de behandeling met HER2-blokkerende middelen bij HER2-positieve mammacarcinoompatiënten door het gebruik van serumbiomarkers, 3D-echocardiografie en cardiale MRI.

Crista Liesting, Jasper J. Brugts, G. Etienne Cramer, Jan Bakker et autres

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