Nobuhisa Minakata

Cold Resection for Superficial Non‐Ampullary Duodenal Epithelial Tumors: Current Evidence and Clinical Perspectives

Yoshiaki Mikuriya, Kohei Takizawa, Nobuhisa Minakata, Kazuo Shiotsuki

Superficial non-ampullary duodenal epithelial tumors (SNADETs) are increasingly treated with endoscopic resection. Although conventional thermal techniques are effective, the thin duodenal wall and distinctive anatomy have driven interest in cold resection techniques that avoid electrocautery-related injury. This narrative review individually appraises cold …

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Efficacy and safety of photodynamic therapy using an ultra-thin endoscope for local failure with esophageal stenosis after chemoradiotherapy for esophageal cancer

Aiji Hattori, Tomohiro Kadota, Hiroki Yamashita, Nobuhisa Minakata et autres

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Retrograde esophageal endoscopic submucosal dissection via gastrostomy without dilation using a thin therapeutic endoscope

Yoshiaki Mikuriya, Kazuo Shiotsuki, Nobuhisa Minakata, Kohei Takizawa et autres

E-Videos Retrograde esophageal endoscopic submucosal dissection via gastrostomy without dilation using a thin therapeutic endoscope. Publication History Received: 13 April 2026 Accepted after revision: 28 May 2026 Article published online: 12 June 2026 © 2026. The Author(s). This is an open access …

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Diagnostic performance of magnifying endoscopy with third-generation narrow-band imaging for early gastric cancer: post hoc analysis of a randomized trial (3G detection trial)

Nobuhisa Minakata, Tomohiro Kadota, Seiichiro Abe, Noriya Uedo et autres

BACKGROUND: In this study, we investigated the diagnostic performance of magnifying endoscopy (ME) with third-generation narrow-band imaging (3G-NBI) for early gastric cancer (EGC), primarily in patients with Helicobacter pylori eradication. METHODS: This was a post hoc analysis of a multicenter, randomized trial …

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Efficacy of high-dose triamcinolone acetonide injection for stricture prevention after wide-field esophageal endoscopic submucosal dissection

Kazuo Shiotsuki, Kohei Takizawa, Nobuhisa Minakata, Yuichiro Mikuriya et autres

Recovery of IR700 Fluorescence After Near-Infrared Photoimmunotherapy: Discovery and Mechanistic Insights

Hideki Tanaka, Shuhei Okuyama, Ken Shirota, Mayumi Sugahara et autres

Background/Objectives: Near-infrared photoimmunotherapy (NIR-PIT) is a molecularly targeted cancer therapy that employs antibody–photoabsorber conjugates (APCs) comprising the photosensitizer IRDye700DX (IR700) and tumor-specific antibodies. Following near-infrared (NIR) light irradiation, IR700 undergoes structural modification, inducing selective and rapid necrotic cell death. In mouse tumor …

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Objective Assessment of Visibility of Colorectal Lesions Using Eye Tracking for New Image‐Enhanced Endoscopy Observation

Aiji Hattori, Hiroaki Ikematsu, Hiroki Yamashita, Takuma Oguro et autres

BACKGROUND AND AIM: This study aimed to objectively evaluate colorectal lesion visibility using white-light imaging (WLI), narrow-band imaging (NBI), and texture and color enhancement imaging (TXI) with an eye tracking system. METHODS: Twelve endoscopists assessed 120 images of 30 colorectal lesions (29 …

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Calibrated small-caliber-tip transparent hood enables rescue of discontinued colorectal endoscopic submucosal dissection

Yoshiaki Mikuriya, Kazuo Shiotsuki, Nobuhisa Minakata, Kohei Takizawa et autres

Colorectal endoscopic submucosal dissection (ESD) is becoming a standard treatment worldwide. Although this procedure is generally safe and effective, it can be technically challenging in certain situations, particularly in the case of severe submucosal fibrosis [ 1 ] [ 2 ]. Although …

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Underwater endoscopic submucosal resection with a ligation device for a duodenal neuroendocrine tumor

Yoshiaki Mikuriya, Kazuo Shiotsuki, Nobuhisa Minakata, Kohei Takizawa et autres

Endoscopic submucosal resection with ligation (ESMR-L) is a modified endoscopic mucosal resection technique that uses a band-ligation device, and it is effective for small duodenal neuroendocrine tumors (NETs [ 1 ] [ 2 ]). Notably, however, the tapered, tube-like shape of conventional …

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Endoscopic balloon tamponade for massive bleeding from aorto-esophageal fistula: a simple technique for rapid hemostasis

Yoshiaki Mikuriya, Kazuo Shiotsuki, Takanori Hama, Nobuhisa Minakata et autres

An aorto-esophageal fistula after chemoradiotherapy (CRT) for esophageal cancer is fatal [ 1 ] [ 2 ]. Early diagnosis and prompt intervention are required for survival [ 3 ]. Endoscopic approaches have been sporadically reported; however, a standardized strategy has not been …

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Endoscopic combination therapy with photodynamic therapy and endoscopic resection for wide circumferential local recurrence after radiotherapy for esophageal cancer

Nobuhisa Minakata, Tomohiro Kadota, Hiroki Yamashita, Takashi Watanabe et autres

Background and Aims: For wide-circumferential local recurrence after chemoradiotherapy or radiotherapy (RT) for esophageal squamous cell carcinoma (ESCC), salvage surgery is performed, but combination therapy with photodynamic therapy (PDT) and endoscopic resection (ER) could be an alternative treatment for a T1b-T2 lesion. …

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The Efficacy of Texture and Color Enhancement Imaging Observation in the Detection of Colorectal Lesions: A Multicenter, Randomized Controlled Trial (deTXIon Study)

Naoya Toyoshima, Taku Sakamoto, Kensuke Shinmura, Kinichi Hotta et autres

BACKGROUND & AIMS: Colonoscopy is the gold standard for detecting and resecting adenomas and early-stage cancers to reduce colorectal cancer (CRC) incidence and mortality rates. This study aimed to confirm the superiority of texture and color enhancement imaging (TXI) over white light …

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