Muhammad Rashad

Unraveling the Regenerative Proteomic Signature of Helix aspersa ’s Slime in Human Dermal Fibroblasts by Data-driven Proteomics Approach

Muhammad Rashad, Alessia Ricci, Marwa Balaha, Zsuzsanna Darula et autres

Abstract Proteins orchestrate essential cellular processes, including metabolism, communication, survival, and regeneration, making proteomic profiling a powerful strategy to elucidate complex biological responses. Snail slime (SnS) has emerged as a bioactive material with documented pro-healing, antioxidant, and anti-inflammatory properties; however, its effects …

it, Égypte, hu (code pays fourni par la source)

Nature’s Synergy: Cellular and Molecular Evaluation of Snail Slime and Its Principal Component, Glycolic Acid, on Keratinocytes, with Preliminary Evidence from Endothelial Cells

Muhammad Rashad, Alessia Ricci, Serena Pilato, Amelia Cataldi et autres

Snail slime (SS) is a natural secretion rich in bioactive components such as glycoproteins, hyaluronic acid, glycolic acid (GA), and antimicrobial peptides. GA, a key component of SS, is known for its exfoliative properties. This study investigates SS's effects on keratinocytes (HaCaT) …

it, Égypte (code pays fourni par la source)

Characterization of mucins, glycosaminoglycans, and bioactive compounds in Helix aspersa’s slime by spectroscopic and biochemical analysis

Michele M. Ciulla, Muhammad Rashad, Mattia Spano, Luisa Mannina et autres

• SS is rich in biological macromolecules, including mucins and glycosaminoglycans. • NMR, FT-IR, and Raman confirm mucins, glycosaminoglycans, and peptides in SS. • SS inhibits the cholinesterases, tyrosinase, amylase and glucosidase enzymes. • SS is a rich source of phenolic compounds …

it, tr (code pays fourni par la source)

Development and characterization of a new cosmetic formulation enriched with optimized Thanaka bark extract (H. crenulata)

Lucrezia Di Nicolantonio, Dolores Vargas Peregrina, Muhammad Rashad, Roberta Censi et autres

it (code pays fourni par la source)

The Quest for Ligands Against Kinesin Motor Protein Eg5

Ahmet Fatih Şahin, Simone Carradori, Alessia Ricci, Muhammad Rashad et autres

ABSTRACT The Kinesin Eg5 motor protein is essential for the formation of the mitotic spindles and chromosome segregation, which is necessary for cell division. The inhibition of Eg5 has emerged as a potential therapeutic strategy for inhibiting the uncontrolled proliferation of cancer …

tr, it (code pays fourni par la source)

Big Data for Sustainability: Examining the Role of Big Data Governance in Enhancing Sustainable Performance

Hafiz Anees Afzal, Muhammad Rashad, Hafiz Khalil Ur Rehman, Muhammad Tufail et autres

The aim of this study is to identify the gap in the literature regarding the role of big data characteristic on the sustainable performance of the organization. In this research, the data were collected from public and private hospitals of Malaysia that …

lt, pk (code pays fourni par la source)

From Nature to Nurture: The Science and Applications of Snail Slime in Health and Beauty

Muhammad Rashad, Simone Sampò, Amelia Cataldi, Susi Zara

BACKGROUND: Snail slime (SS), a complex biological substance produced by various snail species, has garnered significant attention in recent years due to its diverse applications in health, cosmetics, and biotechnology. AIMS: Our previous review focused on the biological activities of SS, while …

it (code pays fourni par la source)

Pollution indicators and human health risk assessment of fluoride contaminated drinking groundwater in southern Pakistan

Shakeel Ahmed Talpur, Muhammad Rashad, Aziz Ahmed, Gianluigi Rosatelli et autres

This study investigated fluoride contamination in groundwater and associated health risks in the Badin district of Pakistan. Fifty-seven groundwater samples were analyzed for fluoride, turbidity, iron, and total dissolved solids (TDS). Pollution indices and health risk models were employed to assess contamination …

it, us, cn, es (code pays fourni par la source)

Exploration of neuroprotective and cognition boosting effects of Mazus pumilus in Alzheimer’s disease model

Malik Saadullah, Jahan Ara Batool, Muhammad Rashad, Muhammad Asif et autres

Abstract Objectives Mazus pumilus (MP) an Asian flowering plant, known for various reported pharmacological activities including antioxidant, anti-nociceptive, anti-inflammatory, anticancer, antibacterial, antifungal, and hepatoprotective effects. This study focused on further exploring Mazus pumilus’ s methanol leaf extract (MPM) for bioactive principles and …

pk, it (code pays fourni par la source)

Isatin-based ibuprofen and mefenamic acid Schiff base derivatives as dual inhibitors against urease and α–glucosidase: In vitro, in silico and cytotoxicity studies

Saima Daud, Obaid‐ur‐Rahman Abid, Malik Saadullah, M. Fakhar-e-Alam et autres

α-Glucosidase and urease inhibitors have emerged as crucial for developing therapeutic drugs targeting diabetes and gastrointestinal disorders. This study reports on new series of ibuprofen and mefenamic acid Schiff base derivatives incorporating isatin as dual inhibitors of α-glucosidase and urease enzymes. These …

pk, it, sa (code pays fourni par la source)

Antitumor activity of zinc oxide nanoparticles fused with green extract of Nigella sativa

M. Fakhar-e-Alam, Irsa Amjad, Malik Saadullah, Muhammad Nawaz Tahir et autres

Zinc oxide nanoparticles have attracted considerable attention as promising candidates in various fields, especially in the realm of medical science. In the present experimental study, the co-precipitation method was used to synthesize chemical and green ZnO NPs. Zinc nitrate Zn (NO3)2 served …

pk, sa, it (code pays fourni par la source)

Biological activities of gastropods secretions: snail and slug slime

Muhammad Rashad, Simone Sampò, Amelia Cataldi, Susi Zara

Gastropods, a mollusk class including slugs and snails, represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates. They can be classified as aquatic and terrestrial animals having coiled shells, although some species have reduced or …

it (code pays fourni par la source)