Sophia V. Tachmitzi

Optical Coherence Tomography Angiography (OCTA) of the eye: A review on basic principles, advantages, disadvantages and device specifications

Aristotle G. Koutsiaris, Vasilios Batis, Georgia Liakopoulou, Sophia V. Tachmitzi et autres

Optical Coherence Tomography Angiography (OCTA) is a relatively new imaging technique in ophthalmology for the visualization of the retinal microcirculation and other tissues of the human eye. This review paper aims to describe the basic definitions and principles of OCT and OCTA …

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Serpin Family E Member 1 Tag Single-Nucleotide Polymorphisms in Patients with Diabetic Nephropathy: An Association Study and Meta-Analysis Using a Genetic Model-Free Approach

Maria Tziastoudi, Efthimios Dardiotis, Georgios Pissas, Georgios Filippidis et autres

Background: Many lines of evidence highlight the genetic contribution on the development of diabetic nephropathy (DN). One of the studied genes is SERPINE1 whose the role in the risk of developing DN remains questionable. In order to elucidate the contribution of SERPINE1 …

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Blood flow velocity comparison in the eye capillaries and postcapillary venules between normal pregnant and non-pregnant women

Stamatina Moka, Aristotle G. Koutsiaris, Antonios Garas, Ioannis E. Messinis et autres

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The contribution of genetic variants of SLC2A1 gene in T2DM and T2DM-nephropathy: association study and meta-analysis

Ioannis Stefanidis, Maria Tziastoudi, Evangelia E. Tsironi, Efthimios Dardiotis et autres

An association study was conducted to investigate the relation between 14 variants of glucose transporter 1 gene (SLC2A1) and the risk of type 2 diabetes (T2DM) leading to nephropathy. We also performed a meta-analysis of 11 studies investigating association between diabetic nephropathy …

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SLC2A1 Tag SNPs in Greek Patients with Diabetic Retinopathy and Nephropathy

Vasileios Siokas, Anatoli Fotiadou, Efthimios Dardiotis, Maria G. Kotoula et autres

Backround: Genetic variants are implicated in the development of diabetic retinopathy (DR) and nephropathy (DN). The role of solute carrier family 2-facilitated glucose transporter member 1 (SLC2A1), also known as glucose transporter (GLUT1), on DR and DN remain controversial. OBJECTIVE: Examination of …

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Plasminogen Activator Inhibitor Type-1 Tag Single-Nucleotide Polymorphisms in Patients with Diabetes Mellitus Type 2 and Diabetic Retinopathy

Vasileios Siokas, Efthimios Dardiotis, Thomas Sokolakis, Maria G. Kotoula et autres

Background: There is accumulating evidence for genetic susceptibility to the development of diabetic retinopathy (DR). The role of plasminogen activator inhibitor-1 (PAI-1) in DR risk remains controversial.Objective: The present study was designed to investigate possible influence of PAI-1 gene region polymorphisms on …

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Supplementary Material for: SLC2A1 Tag SNPs in Greek Patients with Diabetic Retinopathy and Nephropathy

Vasileios Siokas, Anastasia N. Fotiadou, Efthimios Dardiotis, Maria G. Kotoula et autres

Backround: Genetic variants are implicated in the development of diabetic retinopathy (DR) and nephropathy (DN). The role of solute carrier family 2-facilitated glucose transporter member 1 (SLC2A1), also known as glucose transporter (GLUT1), on DR and DN remain controversial. Objective: Examination of …

Plasminogen Activator Inhibitor Type-1 Tag Single-Nucleotide Polymorphisms in Patients with Diabetes Mellitus Type 2 and Diabetic Retinopathy

Vasileios Siokas, Efthimios Dardiotis, Thomas Sokolakis, Maria G. Kotoula et autres

Background: There is accumulating evidence for genetic susceptibility to the development of diabetic retinopathy (DR). The role of plasminogen activator inhibitor-1 (PAI-1) in DR risk remains controversial. Objective: The present study was designed to investigate possible influence of PAI-1 gene region polymorphisms …

Association between Polymorphisms and Haplotypes in AKR1B1 and Diabetes Type 2 leading to Complications

Sophia V. Tachmitzi, Evangelia E. Tsironi, Maria G. Kotoula, Efthimios Dardiotis et autres

Background: A candidate-gene association study in a south eastern Mediterranean population was conducted to investigate the association of five AKR1B1 gene variants (rs2259458 G/T, rs2734653 G/A, rs2670230 C/A, rs1790998 C/A, rs17188118 A/C) with i) diabetes progression and ii) risk of diabetes leading …

Wall shear stress quantification in the human conjunctival pre-capillary arterioles in vivo

Aristotle G. Koutsiaris, Sophia V. Tachmitzi, Nick Batis

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THAP1 mutations in a Greek primary blepharospasm series

Georgia Xiromerisiou, Efthimios Dardiotis, Evangelia E. Tsironi, Georgios M. Hadjigeorgiou et autres

Benign essential blepharospasm (BEB) is an adult onset focal dystonia that manifests as forced involuntary eyelid closure usually starting between the fifth and the seventh decade [1]. The frequency is rare; affecting around 1 in 20,000 people, where most of the cases …

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European ST80 community-associated methicillin-resistant Staphylococcus aureus orbital cellulitis in a neonate

Evangelia E. Tsironi, Fani Zacharaki, Ioanna N. Grivea, Sophia V. Tachmitzi et autres

BACKGROUND: Methicillin-resistant Staphylococcus aureus is a serious cause of morbidity and mortality in hospital environment, but also, lately, in the community. This case report is, to our knowledge, the first detailed description of a community-associated methicillin-resistant S. aureus ST80 orbital cellulitis in …

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