Yupan Bai

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying et autres

Intratumoral bacteria are increasingly recognized as integral and dynamic components of the tumor microenvironment (TME), with profound implications for tumor initiation, progression, metastasis, immune remodeling, and therapeutic response. These microorganisms may originate from mucosal barrier breaches, hematogenous or lymphatic dissemination, local migration …

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β-hydroxybutyrate potentiates anti-tumor immunity by modulating cytotoxic CD8+ T cell responses

Yupan Bai, Han Xue, Yujie Bao, Yue Pan et autres

Ketogenic diets (KDs) have been reported to influence tumor progression through metabolic and immunological modulation of the tumor microenvironment. β-hydroxybutyrate (βOHB), the predominant ketone body elevated by KD, functions not only as an energy substrate but also as a potent signaling metabolite. …

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β-hydroxybutyrate potentiates anti-tumor immunity by modulating cytotoxic CD8+ T cell responses

Yupan Bai, Han Xue, Yujie Bao, Yue Pan et autres

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Risk factors analysis for progression to severe hepatitis in acute hepatitis E: a retrospective study of 146 hospitalized cases

Jiawei Chen, Donglin Yin, Yuanyuan Zhou, Yupan Bai et autres

BACKGROUND: Hepatitis E virus (HEV) infection typically presents as a self-limiting acute hepatitis, but a subset of patients may progress to severe hepatitis, with potential progression to liver failure or even death. Identifying clinical predictors of such severe progression is essential for …

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BBIBP-CorV vaccination accelerates anti-viral antibody responses in heterologous Omicron infection: A retrospective observation study in Shanghai

Yu-Jie Bao, Liheng He, Benjie Miao, Zhengrong Zhong et autres

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BBIBP-CorV Vaccination Reduces COVID-19 Severity Rate and Accelerates Anti-Viral Antibody Responses in Heterologous Omicron Infection

Yu-Jie Bao, Liheng He, Benjie Miao, Zhengrong Zhong et autres

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Retrospective study of characteristics and management of pyogenic liver abscess during 5 years' experience.

Zhou Yuanyuan, Guanzhu Lu, Yupan Bai, Yu-Jie Bao et autres

was the predominant pathogen in pyrogenic liver abscesses, especially in patients with diabetes; and patients with hyperglycemia had poor outcome.

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Discipline Education from “Natural Person” to “Social Person”

Yupan Bai

The individual is the unity of nature and sociality, and sociality is the essential attribute of the individual.Induced by using high power, speech and school discipline rules of three kinds of external forces that affect the students' physical behavior, mood, emotion and …

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Noninvasive indicators predict advanced liver fibrosis in autoimmune hepatitis patients

Lingyan Liu, Junying Cao, Zhengrong Zhong, Yunfei Jiang et autres

BACKGROUND: Liver biopsy is the criterion standard for diagnosing liver fibrosis, but it is not widely used to monitor liver fibrosis because of the invasiveness, risk of complications, and sample errors. Therefore, it is necessary to involve other techniques to monitor liver …

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