Norifumi Shigemoto

Re-incubation of positive anaerobic blood culture bottles for detecting additional anaerobes in polymicrobial bacteremia

Kensuke Shimbara, Hiroki Kitagawa, Kayoko Tadera, Yuta Kuhara et autres

ABSTRACT Anaerobes are important causes of bloodstream infections, but may be overlooked in routine blood culture workflows because of their slow growth and frequent involvement in polymicrobial infections. We hypothesized that in polymicrobial bacteremia, rapidly growing organisms may trigger early blood culture …

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Pharmacokinetics of intravenous metronidazole in the plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients undergoing lower gastrointestinal surgery

Hiroyuki Taogoshi, Hiroki Ohge, Kazuro Ikawa, Shinnosuke Uegami et autres

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Association between an inpatient oral self-care promotion programme and hospital-acquired infections: a propensity score-matched cohort study

Hiromi Nishi, Hiroyuki Kawaguchi, Noriaki Ide, Syuichi Munenaga et autres

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Clinical and molecular characteristics of Streptococcus agalactiae bacteremia in nonpregnant adults: a single-center analysis over 16 years in Hiroshima, Japan

Hiroki Kitagawa, Satoshi Nakano, Kayoko Tadera, Yuta Kuhara et autres

PURPOSE: Molecular epidemiological data on Streptococcus agalactiae (Group B Streptococcus [GBS]) causing bacteremia in non-pregnant adults in Japan remain limited. This study elucidated the clinical characteristics and molecular epidemiology of GBS strains causing bacteremia in this population. METHODS: Data on non-pregnant adults …

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Evaluating the sensitivity of the Wako β-D-glucan assay for the diagnosis of candidemia caused by Candida parapsilosis

Yuta Kuhara, Hiroki Kitagawa, Kayoko Tadera, Keitaro Omori et autres

Candidemia poses diagnostic challenges because of non-specific symptoms and low sensitivity of blood cultures. The Wako (1,3)-β-D-glucan (BDG) assay was recently introduced in Europe; however, its diagnostic performance for Candida parapsilosis compared to that of the Fungitell assay, which has demonstrated lower …

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Clinical characteristics of Parvimonas micra bacteremia in Japan: A single-center case series and literature review

S Inada, Hiroki Kitagawa, Keitaro Omori, Kayoko Tadera et autres

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P-1688. Prevalence of Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum along with antimicrobial susceptibility patterns of Mycoplasma hominis in vaginal samples from pregnant women in Japan

Hiroki Kitagawa, Kayoko Tadera, Mitsuyasu Ikeda, Norifumi Shigemoto et autres

Abstract Background Information on Mycoplasma hominis resistance is currently limited in Japan. Therefore, this study investigated the antimicrobial susceptibility of M. hominis in clinical samples, along with the prevalence of M. hominis and Ureaplasma spp. in vaginal samples. Methods Vaginal samples from …

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P-1608. Inactivating Effect of 222-nm Far Ultraviolet-C Irradiation on Aerosolized SARS-CoV-2 and SARS-CoV-2 in Solution

Hiroki Kitagawa, Toshihito Nomura, Keitaro Omori, Norifumi Shigemoto et autres

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted by droplets, aerosols, and contact. Recent studies have demonstrated the effect of 254-nm, 265-nm, and 280-nm UVC on inactivating aerosolized SARS-CoV-2. This study aimed to investigate the in vitro efficacy of …

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Clinical and Microbiological Characteristics of Patients with Desulfovibrio spp. Bacteremia in a Japanese Tertiary Hospital: A Case Series

Hiroki Kitagawa, Kayoko Tadera, Keitaro Omori, Takuji Omoto et autres

We retrospectively analyzed nine cases of Desulfovibrio spp. bacteremia at a Japanese tertiary hospital: five cases were caused by D. fairfieldensis and four by D. desulfuricans (three MB and one Essex 6 genotype). Intra-abdominal infection was the most common source of infection. …

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Longitudinal Evaluation of Serum Varicella-zoster Virus Viral Load in a Woman with Systemic Lupus Erythematosus Complicated by a Visceral Disseminated Varicella-zoster Virus Infection: A Case Report

Takuji Omoto, Hiroki Kitagawa, Keitaro Omori, Kayoko Tadera et autres

Visceral disseminated varicella-zoster virus infection (VD-VZV) is a rare but life-threatening condition, and treatment-response monitoring has not yet been established. We report a case of a 47-year-old woman with systemic lupus erythematosus who developed primary varicella complicated by VD-VZV during prednisolone and …

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Impact of antimicrobial prophylaxis in colorectal cancer surgery on the gut and oral microbiome and resistome: A prospective observational cohort study

Hiroki Kitagawa, Toshiki Kajihara, Koji Yahara, Norikazu Kitamura et autres

• Perioperative antibiotic prophylaxis induced pronounced and lasting shifts in oral and gut microbial communities. • Antibiotic exposure reduced microbial diversity and anaerobes while expanding Enterococcus, Limosilactobacillus , and Lacticaseibacillus . • The total abundance of antibiotic resistance genes significantly increased and …

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Delayed anastomotic leakage after short-course radiotherapy in a 91-year-old patient with rectal cancer

Yuta Kuhara, Shinnosuke Uegami, Masahide Miyata, Hirofumi Doi et autres

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