Chiara Marrone

Lung function and exercise capacity in single ventricle patients post Fontan palliation and potential role of diaphragm ultrasound imaging

Paula Festa Cilveti, Chiara Marrone, Lamia Ait-Alì, Luca Bastiani et autres

AIMS: Patients with Fontan circulation have reduced functional capacity, due to a reduced cardiac output, but also to an abnormal lung function and respiratory muscle weakness. This study aimed to assess lung function and exercise capacity in a cohort of patients with …

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MRI predictors of diastolic dysfunction and right ventricle end diastolic pressure in repaired tetralogy of Fallot

Chiara Marrone, Maria Luisa Parisella, Francesca De Angelis, Ketty Savino et autres

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Unveiling ccTGA complexity: CMR and 3D modelling for surgical planning—a case series

Irene Cao, Vera Cetera, Gaia Viganò, Chiara Marrone et autres

Aims: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect characterized by atrioventricular and ventriculoarterial discordance and frequently associated with heterogeneous anatomical anomalies. This variability makes surgical indication and strategy particularly complex, requiring accurate preoperative anatomical and …

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Percutaneous implantation of self-expanding pulmonary valves: results from real-life experience of the Venus-P valve Registry of the Italian Society of Pediatric Cardiology (SICPED)

Mara Pilati, Angelo Fabio D’Aiello, Maria A. Chessa, Giuseppe Santoro et autres

Background: Self-expandable valves may have a significant impact on the feasibility of transcatheter treatments of RVOT dysfunction. Venus P valve is the first autoexpadable Valve that received CE mark in 2022. Here, we are reporting on a multicenter data collection about patients …

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Atrial Fistulas as Unusual Cause of Paradoxical Embolism: Prevalence and Percutaneous Treatment

Kristian Ujka, Alessandra Pizzuto, Chiara Marrone, Massimiliano Cantinotti et autres

BACKGROUND: Atrial fistulas are an utmost rare cause of right-to-left shunt (RLS) and may be potentially associated with increased risk of paradoxical embolism. OBJECTIVE: This study aimed to assess prevalence, anatomical features and transcatheter treatment of atrial fistulas in a large cohort …

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Sex Differences in Children and Adolescents With Hypertrophic Cardiomyopathy

Gabrielle Norrish, Ella Field, Elena Cervi, Olga Boleti et autres

BACKGROUND: Sex differences have been described in adults with hypertrophic cardiomyopathy (HCM), but it is unknown if similar differences exist in childhood-onset disease. OBJECTIVES: This study aimed to investigate the influence of biological sex on the clinical characteristics and outcomes of children …

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Recommendations for cardiovascular magnetic resonance and computed tomography in congenital heart disease: a consensus paper from the CMR/CCT Working Group of the Italian Society of Pediatric Cardiology and the Italian College of Cardiac Radiology endorsed by the Italian Society of Medical and Interventional Radiology (Part II)

Pierluigi Festa, Luigi Lovato, Francesco Bianco, Annalisa Alaimo et autres

Cardiovascular magnetic resonance (CMR) and computed tomography (CCT) are advanced imaging modalities that recently revolutionized the conventional diagnostic approach to congenital heart diseases (CHD), supporting echocardiography and often replacing cardiac catheterization. This is the second of two complementary documents, endorsed by experts …

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Electrophysiological assessment of atrial tachycardia substrates in patients with repaired tetralogy of Fallot

Gianluca Mirizzi, Pietro Paolo Tamborrino, Andrea P. Rossi, Umberto Startari et autres

Abstract Introduction Adults with repaired tetralogy of Fallot (rToF) are most often referred to Adult Congenital Heart Disease centers for atrial tachycardia (AT) and radiofrequency catheter ablation (RFCA) is often required. A systematic evaluation of the mechanisms and recurrences of arrhythmias in …

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Systematic right ventricular electrophysiologic evaluation in patients with repaired tetralogy of Fallot before pulmonary valve replacement

Gianluca Mirizzi, Pietro Paolo Tamborrino, Laura Ridolfi, Andrea P. Rossi et autres

Abstract Introduction Adults with repaired tetralogy of Fallot (rToF) are prone to develop ventricular tachycardia (VT) in adulthood, due to reentry related to slowly conducting anatomical isthmuses (SCAI). Pulmonary valve replacement (PVR) in patients without history of VT, may lead to obliteration …

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Impact of 4D-Flow CMR Parameters on Functional Evaluation of Fontan Circulation

Lamia Ait-Alì, Nicola Martini, Elisa Listo, Elisa Valenti et autres

Abstract We sought to evaluate the potential clinical role of 4D-flow cardiac magnetic resonance (CMR)-derived energetics and flow parameters in a cohort of patients’ post-Fontan palliation. In patients with Fontan circulation who underwent 4D-Flow CMR, streamlines distribution was evaluated, as well a …

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Personalized Approach in Transcatheter Palliation of Congenital Heart Disease with Duct-Dependent Pulmonary Circulation: Right Ventricular Outflow Tract Stenting vs. Arterial Duct Stenting

Silvia Teresa Scalera, Alessandra Pizzuto, Pietro Marchese, Massimiliano Cantinotti et autres

Despite significant improvements in techniques, the treatment of neonates and infants with congenital heart disease resulting in duct-dependent pulmonary circulation is still significantly challenging. Despite current trends toward early primary surgical repair, temporary palliation is still necessary in those patients who are …

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Overcoming Underpowering in the Outcome Analysis of Repaired—Tetralogy of Fallot: A Multicenter Database from the CMR/CT Working Group of the Italian Pediatric Cardiology Society (SICPed)

Lamia Ait-Alì, Benedetta Leonardi, Annalisa Alaimo, Giovanna Baccano et autres

Background: Managing repaired tetralogy of Fallot (TOF) patients is still challenging despite the fact that published studies identified prognostic clinical or imaging data with rather good negative predictive accuracy but weak positive predictive accuracy. Heterogeneity of the initial anatomy, the surgical approach, …

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