Susann Skovbjerg

Clinical evaluation of artificial intelligence for diagnostics of antibiotic-resistant bacteria

Magnus Hessel, Juan S. Inda-Díaz, A Sjöberg, Francisco Salvà‐Serra et autres

Abstract Antimicrobial resistance is a public health challenge, driving the need for rapid, cost-effective diagnostic support tools. Artificial intelligence (AI) may enable prediction of susceptibility to untested antibiotics from known susceptibility results, but prospective clinical validation is required before routine use. We …

se, au (code pays fourni par la source)

Invasive pneumococcal disease unmasks monoclonal immunoglobulins and antibody deficiencies: a multicenter prospective study in adults

Tor Härnqvist, Karin Bergman, Åsa Mellgren, Magnus Brink et autres

Immunoglobulins (Ig) are essential for protection against invading pneumococci but are not routinely analyzed in patients with invasive pneumococcal disease (IPD). In this prospective study, we assessed the prevalence of monoclonal Ig (M protein) and analyzed Ig concentrations in sera from 156 …

se (code pays fourni par la source)

Epidemiology of invasive pneumococcal disease in Southwest Sweden during the first eleven years after the introduction of general childhood pneumococcal vaccination

Tor Härnqvist, Karin Bergman, Erik Backhaus, Mats Dahl et autres

BACKGROUND: Invasive pneumococcal disease (IPD) still causes significant morbidity and mortality. In this study, we describe incidence, risk factors, manifestations, and outcome of IPD in Southwest Sweden during the first eleven years after the introduction of conjugate pneumococcal vaccines in the childhood …

se (code pays fourni par la source)

Data for "Epidemiology of invasive pneumococcal disease in Southwest Sweden during the first eleven years after the introduction of general childhood pneumococcal vaccination"

Tor Härnqvist, Karin Bergman, Erik Backhaus, Mats Dahl et autres

This dataset contains pseudonymised data on sex, age, clinical manifestations, and comorbidities for 2,280 individuals with invasive pneumococcal disease (IPD) in Region Västra Götaland during the post-introduction period following the inclusion of pneumococcal vaccination in the childhood immunisation programme in 2009 through …

it, se (code pays fourni par la source)

Data for "Epidemiology of invasive pneumococcal disease in Southwest Sweden during the first eleven years after the introduction of general childhood pneumococcal vaccination"

Tor Härnqvist, Karin Bergman, Erik Backhaus, Mats Dahl et autres

This dataset contains pseudonymised data on sex, age, clinical manifestations, and comorbidities for 2,280 individuals with invasive pneumococcal disease (IPD) in Region Västra Götaland during the post-introduction period following the inclusion of pneumococcal vaccination in the childhood immunisation programme in 2009 through …

it, se (code pays fourni par la source)

Clinical presentation and recent health care contacts in patients with invasive group a streptococcal infection, Western Sweden 2020–2024

Lars Gustavsson, Petter Söderlund, Susann Skovbjerg, Ulrika Snygg‐Martin

Background Cases of invasive group A streptococcal infections (iGAS) increased dramatically in Sweden and other high-income countries during 2023 and 2024. Changing epidemiology and stricter antibiotic stewardship policies are suggested to contribute to this increase.Objectives To describe the clinical presentation and previous …

se (code pays fourni par la source)

Urine bioassay optimisation to assess the association between antimicrobial exposure, pneumococcal carriage and antimicrobial resistance among hospitalised children in Malawi

Susann Skovbjerg, Comfort Brown, Andrew A. Mataya, Jacquline Msefula et autres

BACKGROUND: Understanding antibiotic exposure in low-income settings is crucial when designing and evaluating field research on bacterial carriage and antimicrobial resistance. We evaluated the concordance between reported pre-hospitalisation antibiotic use and antimicrobial activity in urine from children presented with acute respiratory infection …

se, gb, Malawi (code pays fourni par la source)

Healthcare workers´ perspectives on antibiotic utilization in children under five years of age in the Eastern Democratic Republic of the Congo

Jeannière Tumusifu Manegabe, Rose Mwangi, John Mulindwa, David Sumaili et autres

Antimicrobial resistance remains a pressing global challenge, driving efforts worldwide to reduce antibiotic consumption and mitigate its emergence and spread. The aim of this study was to describe how utilizing antibiotics for children under five years of age in the Democratic Republic …

République démocratique du Congo, Tanzanie, se, au, id, no (code pays fourni par la source)

Epidemiology of invasive pneumococcal disease in western Sweden during the first 11 years after the introduction of general childhood pneumococcal vaccination

Tor Härnqvist, Karin Bergman, Erik Backhaus, Mats Dahl et autres

se (code pays fourni par la source)

Surface-Shaving of Staphylococcus aureus Strains and Quantitative Proteomic Analysis Reveal Differences in Protein Abundance of the Surfaceome

Anders Karlsson, Leonarda Achá Alarcón, Beatriz Piñeiro-Iglesias, Gunnar Jacobsson et autres

Staphylococcus aureus is a pathogen known to cause a wide range of infections. To find new targets for identification and to understand host–pathogen interactions, many studies have focused on surface proteins. We performed bacterial-cell surface-shaving, followed by tandem mass tag for quantitative …

se (code pays fourni par la source)

Household air pollution and pneumococcal density related to nasopharyngeal inflammation in mothers and children in Ethiopia: A cross-sectional study

Henrik Olsson, Mulugeta Tamire, Ebba Samuelsson, Adamu Addissie et autres

BACKGROUND: Three billion people in low- and middle-income countries are exposed to household air pollution as they use biomass fuel for cooking. We investigated the associations between solid fuel use and nasopharyngeal (NP) inflammation, as well as the associations between high pneumococcal …

se, Éthiopie (code pays fourni par la source)

Co-occurrence of bacteria and viruses and serotype distribution of Streptococcus pneumoniae in the nasopharynx of Tanzanian children below 2 years of age following introduction of the PCV13

Matilda Emgård, Maria Andersson, Lucia Gonzales‐Siles, Sia E. Msuya et autres

Introduction Pneumococcal conjugate vaccines have reduced severe disease attributed to vaccine-type pneumococci in children. However, the effect is dependent on serotype distribution in the population and disease development may be influenced by co-occurrence of viral and bacterial pathogens in the nasopharynx. Methods …

se, Tanzanie (code pays fourni par la source)