Victor Marcondes Lopes dos Santos

Comparison of mortality rates from cardiovascular disease and the most common cancers in Brazil in 2019 and 2022: a dimensional approach

Guillaume Bon, Isabela Silva Erthal Vieira, Samuel Santos Souza, Luiza Meireles Teixeira et autres

Bempegaldesleukin Plus Nivolumab Versus Sunitinib or Cabozantinib in Previously Untreated Advanced Clear Cell Renal Cell Carcinoma: A Phase III Randomized Study (PIVOT-09)

Nizar M. Tannir, Maria Nirvana Formiga, Konstantin Penkov, Nikolay Kislov et autres

PURPOSE Bempegaldesleukin (BEMPEG) is a pegylated interleukin (IL)-2 cytokine prodrug engineered to provide controlled and sustained activation of the clinically validated IL-2 pathway, with the goal of preferentially activating and expanding effector CD8+ T cells and natural killer cells over immunosuppressive regulator …

us, br, ru (code pays fourni par la source)

A phase II trial of pembrolizumab plus platinum-based chemotherapy as first-line systemic therapy in advanced penile cancer: HERCULES (LACOG 0218) trial.

Fernando Cotait Maluf, Karine Martins da Trindade, Daniel D’Almeida Preto, Fernando Sabino Marques Monteiro et autres

5009 Background: Over the last six decades, platinum-based chemotherapy has been the standard of care first-line treatment for advanced penile squamous cell carcinoma (PSCC). Advanced PSCC has poor prognosis with limited treatment options. Immune checkpoint inhibitors (ICI) have been associated with improved …

br, us (code pays fourni par la source)

A phase II trial of pembrolizumab combined with platinum-based chemotherapy as first-line systemic therapy in advanced penile cancer: HERCULES (LACOG 0218) trial.

Fernando Cotait Maluf, Karine Martins da Trindade, Daniel D’Almeida Preto, Murilo Luz et autres

TPS14 Background: Penile squamous cell carcinoma (PSCC) is an uncommon malignancy which accounts for 2,300 new cases and 400 deaths annually worldwide. However, in low-income countries from South America, Asia and Africa, incidence corresponds to 10-20% of all malignancies in men. Approximately …

br (code pays fourni par la source)

Induction Chemotherapy and Chemoradiotherapy Combined to ASA vs. Placebo for High-Risk Rectal Cancer: Results of a Randomized Trial

Juliana Ominelli, Rodrigo Otávio Araújo, Marcus Valadão, Mônica Luciana Agostinho Padoan et autres

br (code pays fourni par la source)

Phase II trial of induction chemotherapy plus chemoradiotherapy with aspirin or placebo in high-risk rectal cancer (ICAR).

Juliana Souza, Rodrigo Otávio Araújo, Marcus Valadão, Victor Marcondes Lopes dos Santos et autres

e16131 Background: Induction chemotherapy (IC) followed by chemoradiation (CRT) is an attractive approach in locally-advanced, high-risk rectal cancer. Additionally, aspirin has shown potential to lower recurrence rate in colorectal cancer, and improve outcomes alongside CRT in rectal cancer, with higher rate of …

br (code pays fourni par la source)

Tuberculose articular multifocal acometendo pequenas articulações

Renata Fialho Sampaio, Suzana Grassano Fadel, Victor Marcondes Lopes dos Santos, Myriam Christina Lopes Ferreira et autres

Osteoarticular tuberculosis represents 1%-3% considering all forms of tuberculosis. 90% of the cases appears like a monoarthritis, what turns rare the involvement of more than one articulation. The weight-bearing joints are frequently affected, whereby involvement of the knee and hip account for …

br (code pays fourni par la source)