Stephan Brand

Lung basement membranes are compositionally and structurally altered following resolution of influenza infection

Stephan Brand, Sara Kirkham, Christopher Jagger, Matiss Ozols et autres

Identification of pathways preventing timely recovery from acute respiratory viral infection is under-studied but essential for long-term health. Using unbiased proteomics, we reveal an unexpected, reduction in lung basement membrane proteins 21 days after influenza infection when mice had symptomatically recovered. Basement …

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Time‐ and cost‐effective manufacturing of 3D templates of the pelvis and acetabulum in primary and revision hip arthroplasty using semiautomatic segmentation

Hendrik Pott, Peter Savov, Ricarda Stauß, Julian‐Arman Beheshty et autres

Purpose: To develop and evaluate a time- and cost-efficient workflow for generating three-dimensional (3D) printable models of the pelvis and acetabulum using semiautomated segmentation with free and open-source software. The goal was to enable a streamlined production of individualized models suited for …

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„Bending“ statt Explanting – Operative Versorgung von Oberschenkelschaftschmerzen bei diaphysär verankerter Hüftendoprothese

Birte Schoon, Stephan Brand, Max Ettinger

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CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites

Johannes Stallhofer, Michael Lauseker, L. Waldenmaier, Helga‐Paula Török et autres

Intestinal epithelial overexpression of the Th17 cell chemoattractant CCL20 is implicated in inflammatory bowel disease and influenced by NOD2 mutations in Crohn's disease. Vitamin D metabolites have been shown to ameliorate inflammatory bowel disease. Considering NOD2 mutations in Crohn's disease, we investigated …

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First Description of Sprue-Like Enteropathy due to Azilsartan: A Case Report

Luisa Stoeckli, Markus Köster, Tugce Tuerkmen-Uthayanan, Sergio Cogliatti et autres

Introduction: Sartan-induced enteropathy is an uncommon side effect of treatment with angiotensin II receptor antagonists (ARBs), which has predominantly been described for olmesartan. Case Presentation: For the first time, we describe sartan-induced enteropathy as an adverse drug reaction associated with azilsartan in …

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First Description of Simultaneous Sweet Syndrome and Tracheal Stenosis as Extraintestinal Manifestations in a Patient With Highly Active Ulcerative Colitis

Hala Alrasheed, Eva Markert, Olaf Chan-Hi Kim, Christin Pelzer et autres

Sweet syndrome and tracheal stenosis are very rare extraintestinal manifestations of inflammatory bowel diseases. In this study, we present a patient with ulcerative colitis, who developed Sweet syndrome in combination with an acute tracheal stenosis causing a life-threatening situation requiring admission to …

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Abstract 5839: Mimicking the immunosuppressive tumor microenvironment: a complex primary immune cell tumor killing assay to support candidate vaccine or immunomodulator screening

Stephan Brand, Elizabeth Lieverse, Henry Leonard, Elsenoor J. Klaver et autres

Recent advances in oncology vaccine strategies, from off-the-shelf to personalized approaches offer a promising new weapon in the cancer treatment arsenal. The ability of these vaccines to exploit host immunity by priming and expanding Tumor Associated Antigen (TAA)-specific T cells presents a …

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Analysis of systemic serum vancomycin levels following intraarticular application in primary total joint arthroplasty

Ricarda Stauß, Peter Savov, Seeber GH, Stephan Brand et autres

INTRODUCTION: Periprosthetic joint infection (PJI) is a serious complication following primary total joint arthroplasty (TJA). PJI accounts for 15-25% of revision surgeries, therefore it is associated with PJI is associated with substantial patient morbidity and mortality as well as increased healthcare expenditures …

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Lung basement membranes are compositionally and structurally altered following resolution of acute inflammation

Stephan Brand, Sara Kirkham, Christopher Jagger, Matiss Ozols et autres

Abstract Identification of pathways preventing recovery from acute respiratory viral infection is under-studied but essential for long-term health. Using unbiased proteomics, we reveal an unexpected persistent reduction in lung basement membrane proteins in mice recovered from influenza infection. Basement membrane provides a …

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Illegales Nahrungsergänzungsmittel mit schwerwiegender Leberschädigung

Szilárd György, Sandra Müller, Marlene Zippl, Thorsten Meuthen et autres

Complément alimentaire illégal à l’origine d’une grave lésion hépatique

Szilárd György, Sandra Müller, Marlene Zippl, Thorsten Meuthen et autres

FRI-315 Metabolic dysfunction associated steatotic liver disease with development of decompensated cirrhosis as long-term complication after distal gastric bypass surgery

Pamela Meyer-Herbon, Irina Bergamin, Patrizia Kuenzler, Patrick Folie et autres