Mohamad Hanouneh

Green discoloration of the urine

Haya Al Suradi, Dina R Gonzalez-Hernandez, C. Elena Cervantes, Cynthia M. Soriano et autres

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An Elderly Man with an Unusual Cause of Abdominal Pain and Urinary Retention

Aditi Singh, C. Elena Cervantes, Mohamad Hanouneh

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When childhood anomalies grow up: adult-onset discovery of multicystic dysplastic kidney, a case report

Dina R Gonzalez-Hernandez, Haya Al Suradi, Nickolas Coombs, Christina Tamargo et autres

INTRODUCTION: Multicystic dysplastic kidney (MCDK) is a congenital condition where noncommunicating cysts replace normal renal parenchyma, affecting about 1 in 4,300 live births. Unilateral MCDK is often asymptomatic, it may cause flank pain, hematuria, or hypertension. CASE DESCRIPTION: A 40-year-old male with …

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Sulfadiazine-induced crystalline nephropathy: a case report of a reversible cause of acute kidney injury in advanced HIV

Ziad Alahmadi, C. Elena Cervantes, Mohamad Hanouneh

INTRODUCTION: Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction. Crystal-induced AKI mostly occurs as a result of acute uric acid nephropathy and following the administration of drugs or toxins that are poorly soluble. …

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Sulfadiazine-Induced Crystalline Nephropathy: A Reversible Cause of Acute Kidney Injury in Advanced HIV

Ziad Alahmadi, C. Elena Cervantes, Mohamad Hanouneh

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A Tale of Two Patients with Acute Hyponatremia Following Cyclophosphamide: Case Reports and Pathophysiological Perspectives

Colton Jensen, Christina Tamargo, Mohamad Hanouneh, C. Elena Cervantes

Introduction: Cyclophosphamide (CYC) can lead to both acute and chronic hyponatremia through central and kidney-related mechanisms. This report presents two cases of acute hyponatremia linked to CYC use. Case Description: Case 1: A 70-year-old woman with myelodysplastic syndrome underwent preconditioning for an …

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Metformin and Mayhem: How to Corral the Chaos

Nadia Ijaz, Joshua D. King, Mohamad Hanouneh, Victoria A MacDonald

Introduction: Metformin, the most prescribed glucose lowering medication worldwide, has been used for more than six decades to manage diabetes. Introduced in Europe in the late 1950’s, it made its way to the US in 1995 after intense scrutiny due to the …

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Genetics Meets Infection: A Case of Parvovirus B19-Induced Collapsing FSGS in the Context of APOL1 High-Risk Genotype

Colton Jensen, Nasha Elavia, C. Elena Cervantes, Avi Z. Rosenberg et autres

Introduction: Collapsing focal segmental glomerulosclerosis (cFSGS) is a severe variant of FSGS, often associated with viral infections and linked to high-risk APOL1 genotypes predominantly found in individuals of recent African ancestry. Case Description: A 41-year-old Black female with a history of hypertension …

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Albuminuria Reduction with Low- vs. High-Dosage Empagliflozin: Is More Always Better?

C. Elena Cervantes, Sneha Mehta, Mohamad Hanouneh, Morgan E. Grams

Background: Sodium-glucose co-transporter 2 inhibitors (SGLT2is) reduce albuminuria and improve cardiovascular (CV) and renal outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes. The EMPA-REG OUTCOME trial showed similar CV benefit with both 10 mg and 25 mg doses …

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A Tale of Two Patterns of Membranoproliferative Glomerulonephritis Associated with Chronic Lymphocytic Leukemia

Oluwadamilola Adisa, Aditi Singh, V. Acharya, C. Elena Cervantes et autres

Introduction: Renal involvement in chronic lymphocytic leukemia (CLL) may present as glomerulonephritis (GN), interstitial nephritis, or direct infiltration. GN commonly appears as MPGN or minimal change disease, potentially causing nephrotic syndrome and renal insufficiency. Case Description: A 75-year-old male presented with acute …

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Bladder in the Hole and a Hole in the Bladder: Spigelian Hernia Involving the Urinary Bladder with Mesh Erosion

Aditi Singh, C. Elena Cervantes, Mohamad Hanouneh

Introduction: Bladder involvement within Spigelian hernias is a rare finding, involving herniation of the bladder wall through the Spigelian aponeurosis, often presenting with abdominal pain or urinary tract infections (UTIs). Mesh erosion into the bladder following inguinal hernia repair is also an …

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An atypical cause of amyloidosis: a case of combined heavy and light chain amyloidosis

Dina R Gonzalez-Hernandez, Mohamad Hanouneh, C. Elena Cervantes

BACKGROUND: The International Society of Amyloidosis recognizes 15 types of kidney-related amyloidosis, with most studies identifying immunoglobulin light chain (AL) amyloidosis as the leading cause in over half of these cases. Heavy chain (AH) amyloidosis has been reported in 0.1-2.3% of kidney …

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