Dimitrios D. Dionyssiou

The Greek LYMPH-Q Upper Extremity Module for Breast Cancer-Related Lymphedema: Translation and Cultural Adaptation

Maddalena Robotti, Adriano Fabi, Alexandra Schulz, Shakuntala Savanthrapadian et autres

Combined minimally invasive lymphatic microsurgery and aligned nanofibrillar collagen scaffold for refractory post-traumatic eyelid lymphedema: A case report

Dimitrios D. Dionyssiou, Avra Drougou, Anastasios Topalis, Rebecca Ardemagni et autres

Lymphedema arises from impaired lymphatic drainage, leading to accumulation of protein-rich fluid in the interstitium and progressive soft-tissue fibrosis. Although eyelid lymphedema is rare, it can cause marked functional and aesthetic morbidity, while often proves refractory to conservative measures. We report a …

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Pilot Study: Lymphatic Brain Decongestion: A New Surgical Technique in Alzheimer Disease

Anastasios Topalis, Chrysanthi Bekiari, Efterpi C. Demiri, Dimitrios D. Dionyssiou

Background: Alzheimer disease (AD) is characterized by progressive cognitive function decline and neurodegeneration. Accumulation of amyloid-beta peptides forms plaques leading to brain inflammation and neuronal death. Glymphatic and meningeal lymphatic systems regulate brain fluid homeostasis and affect neurodegeneration by transferring amyloid-beta peptides …

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Epithelioid sarcoma of the hand mimicking Dupuytren's disease: A case report and review of the literature

Athanasios Papas, Ioannis Kaloudis, Stavroula Pervana, Eleni Georgiadou et autres

We report a case of recurrent epithelioid sarcoma in a 30-year-old man whose initial clinical and histological findings were compatible with Dupuytren's contracture. Lymph node spread, distant metastases, and targeted histological examination eventually led to a correct diagnosis. Epithelioid sarcoma should always …

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The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema – study protocol of a pragmatic randomised international multicentre superiority trial

Elisabeth A. Kappos, Yvonne Haas, Alexandra Schulz, Florian Peters et autres

INTRODUCTION: Up to one-fifth of breast cancer survivors will develop chronic breast cancer-related lymphoedema (BCRL). To date, complex physical decongestion therapy (CDT) is the gold standard of treatment. However, it is mainly symptomatic and often ineffective in preventing BCRL progression. Lymphovenous anastomosis …

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Long-term results of lymphedema treatment with Combined lymph node transfer and collagen scaffolds: An Observational Study

Dimitrios D. Dionyssiou, Antonios Tsimponis, Eleni Georgiadou, Konstantina Mamaligka et autres

Aim: Vascularized lymph node transfer (VLNT) accelerates growth factor secretion, lymphatic endothelial cell migration toward the interstitial flow and lymphagiogenesis in a multidirectional pattern. Our observational study aimed to examine the hypothesis that nanofibrillar collagen scaffolds (NCS) combined with VLNT can provide …

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A Novel Approach to Incision Marking in Abdominoplasty Using 3D Printing Technology: A Description of Technique

Ioannis Panagiotis Kyriazidis, Efterpi C. Demiri, Dimitrios D. Dionyssiou, Georgia-Alexandra Spyropoulou et autres

Dear Editor, We read with great interest the article by Mortada et al entitled “A Novel Approach to Incision Marking in Abdominoplasty Using 3D Printing Technology: A Description of Technique.”1 The authors present an innovative technique utilizing 3-dimensional (3D)-printed tools for abdominoplasty …

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LYMPHATIC BRAIN DECONGESTION IN ALZHEIMER’S DISEASE: EXPERIMENTAL PILOT STUDY

Anastasios Topalis, Dimitrios D. Dionyssiou, Chryssa Bekiari, Efterpi C. Demiri

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When Nerves Tell a Different Story: Functional Neurological Disorder (FND) After a Minor Hand Injury

Ioannis Panagiotis Kyriazidis, Efterpi C. Demiri, C. H. Mitsaki, Dimitrios D. Dionyssiou

Hand injuries typically present with localized symptoms. However, we report an unusual case of a 32-year-old female who experienced a transient complete loss of sensation and motor function in her entire left nondominant hand after sustaining a minor 1 cm stab wound …

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Comparing the Impact of Diluents and Injection Techniques on Patient Comfort During Indocyanine Green Lymphangiography: A Prospective Study

Ioannis Panagiotis Kyriazidis, Efterpi C. Demiri, Dimitrios D. Dionyssiou

Background: Indocyanine green (ICG) lymphography, a key diagnostic tool for lymphedema, is influenced by the dilution process of ICG dye, impacting patient experience. Methods and Results: In our study, we assessed three different ICG diluents—water for injection (WFI), normal saline (NS), and …

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The LYMPH Trial - Comparing Microsurgical with Conservative Treatment of Chronic Breast Cancer Associated Lymphedema: Study Protocol of a Pragmatic Randomized International Multicentre Superiority Trial

Elisabeth A. Kappos, Yvonne Haas, Alexandra Schulz, Florian Peters et autres

ABSTRACT Introduction Up to one fifth of breast cancer survivors will develop chronic breast cancer-related lymphedema (BCRL). To date complex physical decongestion therapy (CDT) is the gold standard of treatment. However, it is mainly symptomatic and often ineffective in preventing BCRL progression. …

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Predesigned chimeric deep inferior epigastric perforator and inguinal lymph node flap for combined breast and lymphedema reconstruction: A comprehensive algorithmic approach

Efterpi C. Demiri, Dimitrios D. Dionyssiou, Ioannis Panagiotis Kyriazidis, Avra Drougou et autres

The combined use of a deep inferior epigastric perforator (DIEP) flap coupled with vascularized inguinal lymph nodes (VILNs) for simultaneous breast and lymphedema reconstruction has already been well established, and promising results have been reported. However, a standardized approach for the planning …

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