Swaroopa Deme

Role of lactate albumin ratio in predicting in-hospital mortality in sepsis patients and its comparison with quick sequential organ failure assessment (qSOFA) score – A prospective observational study

Swaroopa Deme, Bhaskar Kakarla, Akula Sushmitha

ABSTRACT Background: Sepsis is defined as a dysregulated host immune response to an infection. According to the WHO in 2017, 49 million sepsis cases and 11 million deaths were reported. The quick Sequential Organ Failure Assessment (qSOFA) score has several disadvantages in …

in (code pays fourni par la source)

Analyzing Factors Influencing Mortality in Acute Respiratory Failure: A Comprehensive Study of 275 Patients

Bhaskar Kakarla, Swaroopa Deme, Ramya Durgam

This is a prospective observational study conducted in a tertiary center from December 2021 to November 2022.Approval was obtained from the Institutional Ethics Committee under reference number PBAC No. 2179/2021.Informed consent was obtained.A total of 275 patients were recruited who met the …

in (code pays fourni par la source)

A rare case of sickle cell disease with musculoskeletal manifestations and normal peripheral smear

Naval Chandra, Sunkesula Abdul Rajak, A. Nanditha, V. Sharanya et autres

Abstract Sickle cell anaemia causes significant mortality and morbidity, with a decrease of 25–30 years in the average life expectancy. Over time, sickle cell disease produces various musculoskeletal abnormalities as a result of chronic anaemia. Ischaemia and infarction are the common complications …

in (code pays fourni par la source)

Comparative Study of Outcomes of COVID-19 Infection in Vaccinated and Unvaccinated Patients- A Retrospective Analysis

Bhaskar Kakarla, Swaroopa Deme, Sugunasree Aakula, Abhilash Naini et autres

Introduction: Vaccine development was the highest priority during the Coronavirus disease 2019 (COVID-19) pandemic. An ideal vaccine should decrease the risk of infection and reduce the incidence and severity of the disease. Risk of disease or infection following COVID-19 vaccination needs to …

Pancreatic Tuberculosis Mimicking a Mass: A Case Report

Swaroopa Deme, Bhaskar Kakarla, Rajani Thakur, Purushotham Ramireddygari et autres

Tuberculosis, a preventable and curable disease caused by Mycobacterium tuberculosis, is the leading infectious cause of mortality worldwide. Organs commonly affected are lungs and extrapulmonary organs like lymph nodes, meninges, bones, genitourinary and gastrointestinal tract. Ileocaecal tuberculosis is the commonest form of …

Role of neutrophil-to-lymphocyte ratio in predicting microvascular complications in type 2 diabetes mellitus

Nandita Gollakota, Swaroopa Deme, Bhaskar Kakarla, M. Nageswara Rao et autres

Background: Tools for early recognition to enable timely intervention and prevention of micro and macrovascular complications are needed in diabetes mellitus. Our study was aimed at assessing the role of neutrophil-to-lymphocyte ratio (NLR) as a tool to identify individuals at risk for …

in (code pays fourni par la source)

Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis

Patrick Vermersch, Luís Brieva, Robert J. Fox, Friedemann Paul et autres

BACKGROUND AND OBJECTIVES: Masitinib is a selective tyrosine kinase inhibitor, targeting innate immune cells (mast cells and microglia) that are involved in the pathophysiology of progressive multiple sclerosis (MS). Study AB07002 assessed oral masitinib in patients with progressive MS who were progressing …

fr, es, pl, de (code pays fourni par la source)

Digital gangrene as an unusual paraneoplastic manifestation of hodgkins lymphoma—a rare case report

Swaroopa Deme, Bhaskar Kakarla, Venkateswar Rao P, Raju Ysn et autres

Abstract Background Hodgkin’s lymphoma presenting with digital ischemia and gangrene is a rare manifestation. Paraneoplastic manifestations are rare in Hodgkin’s lymphoma but can occur in the form of paraneoplastic cerebellar degeneration (PCD) and dermatomyositis/polymyositis. This case report adds an exceptional presentation of …

in (code pays fourni par la source)

Study of serum procalcitonin in patients with sepsis, septic shock and systemic inflammatory response syndrome (SIRS)

Swaroopa Deme, SravanK Appani, Bhaskar Kakarla, Goveen Manda et autres

Background: Sepsis is a complex syndrome caused by an uncontrolled systemic inflammatory response of infectious origin characterized by dysfunction or failure of one or more organs and even death. Procalcitonin (PCT) has been one of the promising markers in bacterial sepsis. Aim: …

in (code pays fourni par la source)

Utility of Cancer ratio (serum LDH: pleural fluid ADA) for predicting malignancy in patients with exudative pleural effusion

Bhaskar Kakarla, Varaprasad Kuruva, Swaroopa Deme, Sekhar Babu Banda et autres

Introduction: Pleural effusion is an accumulation of fluid in the pleural space. It can be transudative or exudative. Mechanisms like alteration in Starling’s forces lead to transudative effusions while inflammation and infiltration by infections, malignancy, connective tissue diseases, etc lead to exudative …

in (code pays fourni par la source)

Clinical profile and predictors of severe bleeding and mortality in dengue fever patients

Swaroopa Deme, Ravi Teja Tejavath, Bhaskar Kakarla

Background: Dengue viral infection is one of the common tropical diseases spread by the bite of infected Aedes aegypti mosquito. Nearly 100 countries and 40% of the world population are at risk of getting dengue fever. Recent 2011 WHO classification categorized this …

Comparison of estimated glomerular filtration rate equations in elderly with chronic kidney disease

Swaroopa Deme, Pardhu Bharath Neelam, Sateesh Killi, Sree Bhushan Raju et autres

Background: Chronic kidney disease (CKD) a growing epidemic in India with limited studies addressing the problem of ideal equation for estimated glomerular filtration rate (eGFR) among elderly Indian patients. Currently, eGFR is calculated employing the CKD Epidemiology Collaboration (CKD-EPI) equations of which …

in (code pays fourni par la source)