Mercedes Chan

La maladie de Kawasaki: des directives cliniques sur le diagnostic et la prise en charge

Audrea Chen, Evelyn Rozenblyum, Nagib Dahdah, Bianca Lang et autres

Résumé La maladie de Kawasaki est une vasculite systémique qui doit être traitée rapidement pour éviter des anévrismes coronaires et les complications cardiaques qui en découlent. Le présent point de pratique propose des directives pour diagnostiquer la maladie de Kawasaki et la …

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Kawasaki disease: practical guidance on diagnosis and management

Audrea Chen, Evelyn Rozenblyum, Nagib Dahdah, Bianca Lang et autres

Kawasaki disease (KD) is a systemic vasculitis that requires prompt treatment to prevent coronary artery aneurysms and subsequent cardiac complications. This practice point presents guidance on the diagnosis and management of KD, including scenarios with severe disease and high risk for developing …

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Work productivity and activity impairment in patients under 18 with juvenile idiopathic arthritis (JIA): the international UCAN CAN-DU prospective study

Deborah A. Marshall, Rodrigo Dal Ben, Gillian Currie, Rae S.M. Yeung et autres

BACKGROUND: To measure the impact, over time, of juvenile idiopathic arthritis (JIA) on the work and daily activities of patients under age 18. METHODS: Data were collected in a prospective international cohort—the Canada-Netherlands Personalized Medicine Network in Childhood Arthritis and Rheumatic Diseases …

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Referral letters to pediatric rheumatology: referral content and impact on triage – an observational study

Alexandra Rydz, Fangfang Fu, Zhe Lü, Mark L. Drew et autres

BACKGROUND: Delays in access to care in rheumatology are well documented. Many factors contribute to these delays and studies in adult populations indicate that incomplete referral letters may play a role. This study aims to describe the content of referral letters to …

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A Tale of Many Canadas: Associations of Ancestry With Juvenile Idiopathic Arthritis Categories and Disease Severity at Presentation to Care

Stephanie Wong, Lori B. Tucker, Kristin Houghton, David A. Cabral et autres

Objective To assess associations of ancestry with juvenile idiopathic arthritis (JIA) categories and clinical Juvenile Arthritis Disease Activity Scores (cJADAS10) at presentation to pediatric rheumatology care in a multicultural country with universal health care. Methods Parents reported their child's ancestry in the …

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Immune checkpoint inhibitors and the pediatric rheumatologist: a pediatric needs assessment

John Storwick, Carrie Ye, Shahin Jamal, Nancy Maltez et autres

BACKGROUND: The use of immune checkpoint inhibitor (ICI) therapy is increasing in pediatric oncology. ICIs can cause rheumatic-immune related adverse events (Rh-irAEs) such as inflammatory arthritis and myositis. Few case reports detail Rh-irAEs and their management in the pediatric population. Our objective …

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Confidence Check: Closing the Educational Gaps in Immune Checkpoint Inhibitors

John Storwick, Carrie Ye, Shahin Jamal, Nancy Maltez et autres

Objectives The growing use of immune checkpoint inhibitors (ICIs) in pediatric oncology has introduced pediatric rheumatologists (PR) to immune-related adverse events (irAEs), including rheumatic-irAEs (Rh-irAEs).[1] These novel conditions prompt a need for learning around their presentation and complex management issues, especially due …

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Immune Checkpoint Inhibitors: A Pediatric Needs Assessment

John Storwick, Carrie Ye, Shahin Jamal, Nancy Maltez et autres

Objectives Immune checkpoint inhibitor (ICI) therapy is increasing in pediatric oncology. Immune-related adverse events (irAEs) can affect various organ systems, including rheumatic-irAEs (Rh-irAEs) such as inflammatory arthritis, myositis, sicca syndrome, systemic lupus erythematosus, sarcoidosis, and vasculitis.[1] Few cases report detail Rh-irAEs and …

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Referral letters to pediatric rheumatology: referral content and impact on triage - an observational study

Alexandra Rydz, Fangfang Fu, Zhe Lü, Mark L. Drew et autres

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Teenage heartache: A 14-year-old with pleuritic chest pain

Ashleigh India Nazareth, Shamma Alzaabi, Mercedes Chan

A 14-year-old transgender male presented with 1 month of worsening intermittent pleuritic chest pain, 2–3 weeks after an upper respiratory infection. A review of systems revealed mild fatigue, low appetite and mild frontal headache without red flags. Examination revealed left-sided ptosis, persistent …

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A decade of progress in juvenile idiopathic arthritis treatments and outcomes in Canada: results from ReACCh-Out and the CAPRI registry

Kelly Nguyen, Julie Barsalou, Daniah Basodan, Michelle Batthish et autres

OBJECTIVE: To assess changes in juvenile idiopathic arthritis (JIA) treatments and outcomes in Canada, comparing 2005-2010 and 2017-2021 inception cohorts. METHODS: Patients enrolled within three months of diagnosis in the Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) and the Canadian …

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Predictors of persisting pain in children with Juvenile Idiopathic Arthritis: a case control study nested in the ReACCh-Out cohort

Tara McGrath, Jaime Guzmán, Lori B. Tucker, Natalie J. Shiff et autres

BACKGROUND: To identify baseline predictors of persisting pain in children with Juvenile Idiopathic Arthritis (JIA), relative to patients with JIA who had similar baseline levels of pain but in whom the pain did not persist. METHODS: We used data from the Research …

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