Dan Luo

Engeletin alleviates doxorubicin-induced cardiotoxicity via the AMPK pathway in mice

Xin Chen, Xing Zhong, Dan Luo, Qingning Huang et autres

Background The extensively employed antineoplastic drug doxorubicin (DOX) is constrained in clinical utilization on account of its severe cardiotoxicity, and there persists a dearth of protective agents against doxorubicin-induced cardiotoxicity (DIC). Engeletin (ENG) is a natural product endowed with multiple biological activities …

cn, us (code pays fourni par la source)

Network pharmacology, machine learning, and experiments uncover β-sitosterol targeting HSP90AA1 in medicinal-edible black soybean against aging

Yuanyuan Jia, Jingyi Yang, Qian Chen, Yuting Yang et autres

Background Aging involves progressive dysregulation of cellular homeostasis, while current anti-aging agents face limitations in specificity and safety. Black soybean, a medicinal-edible substance, contains various bioactive compounds. This study aims to investigate the anti-aging mechanism of its key component, β-sitosterol, through integrated …

cn (code pays fourni par la source)

Perceptions and experiences of a multicomponent traditional Chinese medicine lifestyle medicine program for depression: a qualitative study

Jia Ruan, Xi Chen, Hui Lin Cheng, Wan Yi Qing et autres

BACKGROUND: Depression, a debilitating mental disorder, has become the leading cause of disability worldwide. A growing body of evidence supports the feasibility and effectiveness of multicomponent lifestyle medicine programs for the treatment of depression, including the recent novel multicomponent Traditional Chinese Medicine …

hk, us, cn, my (code pays fourni par la source)

Salt Stress Enhances Aroma Component 2-Acetyl-1-pyrroline in Aromatic Coconut (Cocos nucifera Linn.)

Jinyao Yin, Dan Luo, Cuinan Shi, Hao Ding et autres

L.) is valued in the consumer market primarily for its distinctive fragrance, which is largely attributed to the compound 2-acetyl-1-pyrroline (2AP). The accumulation of 2AP has been observed in several crops, such as rice, when exposed to salt stress. In rice, exposure …

cn, pk (code pays fourni par la source)

Secure Computation Scheme for the Intersection Area of Polygons Resistant to Malicious Participants

Xin Liu, Anyang Qi, Lanying Liang, Dan Luo et autres

In computer vision, the intersection determination of polygonal areas is utilized to segment different regions in an image and assist in detecting the boundaries of the regions. Moreover, the secure computation of the intersection area of polygons can solve the private calculation …

cn (code pays fourni par la source)

The role of personality traits on fear of childbirth in pregnant women: A systematic review and meta-analysis

Tingting Zhang, Rui Wang, Cuicui Yang, Dan Luo

cn (code pays fourni par la source)

Modeling and analysis of active thermal regulation in segmented PCM wall systems for optimizing energy efficiency in severe cold regions

Jingwei Li, Dan Luo, Jiaojio Jia, Dong Li et autres

cn (code pays fourni par la source)

Effect of population aging on pulmonary tuberculosis burden in Zhejiang Province, China: a population-based study

Yuxiao Ling, Wei Wang, Songhua Chen, Yu Zhang et autres

Background: China's aging population poses a growing challenge to disease burden. This study aims to evaluate the impact of population aging on the incidence of pulmonary tuberculosis (PTB) in Zhejiang Province, China. Methods: PTB notified incidence data reported to the National Notifiable …

cn (code pays fourni par la source)

Privacy-preserving computation scheme for the maximum and minimum values of the sums of keyword-corresponding values in cross-chain data exchange

Xin Liu, Hui Gao, Dan Luo, Likai Jia et autres

In the specific value computation scenario of blockchain cross-chain data exchange, participants can organize raw data in the form of data pairs, making the computed specific values become key information for cross-chain collaboration. The main challenges faced in this scenario include: the …

cn (code pays fourni par la source)

Targeting the SMOX/ATP5F1A Axis Ameliorates Mitochondrial Dysfunction in Diabetic Kidney Disease

Dan Luo, Xueqi Liu, Miaoyan Liu, Shu‐Ting Li et autres

Background: Diabetic kidney disease (DKD), the predominant etiology of end-stage renal disease, progresses through renal tubular epithelial cell (RTEC) injury and subsequent fibrosis. Although tubular pathology drives DKD progression, early drivers remain unclear. Transcriptomic analysis of human DKD biopsies revealed tubular spermine …

cn (code pays fourni par la source)

Clinical Status and Idea Analysis of Long Needle Penetration Acupuncture in the Treatment of Stroke Sequelae

Dan Luo, Weifeng Zhao, Jie Zhu, Xinyi Yang

Stroke is an acute cerebrovascular disease with a rapid onset. After a stroke, most patients suffer from motor, sensory, or cognitive impairments of varying degrees, lose their ability to live independently, and their quality of life is seriously affected. This has become …

Privacy-preserving computation protocol of multi-party sets intersection and union for internet of things environments

Xin Liu, Xinyuan Guo, Dan Luo, Ji Wang et autres

cn (code pays fourni par la source)