Accès ouvert
2026
article
OpenAlex
Takashi Uebanso, Kei Kobayashi, Ayumi Masuda, Hitomi Iba et autres
V. parahaemolyticus has several virulence factors, including thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH), and two separate type III secretion systems (T3SSs), T3SS1 and T3SS2. T3SS1 is responsible for cytotoxicity, primarily through the activity of its effector VP1680. To gain a detailed …
jp
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Accès ouvert
2025
article
OpenAlex
Kazuaki Mawatari, Yushi Onoda, Yasuko Kadomura-Ishikawa, Takahiro Emoto et autres
Ultraviolet (UV) disinfection is a powerful method for inactivating viruses. However, comparative wavelength-dependent sensitivities among human viruses and bacteriophages remain poorly characterized. Here, we evaluated the virucidal efficiencies of UV-light emitting diode (UV-LED) against multiple coliphages (MS2, Qβ, PhiX174, and T1) and …
jp, us
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Accès ouvert
2025
article
OpenAlex
Kazuaki Mawatari, Takashi Uebanso, Akira Takahashi, Tetsuya Shiuchi
Ultraviolet B (UVB) light exerts biological effects beyond the skin; however, its influence on systemic energy metabolism remains unclear. We investigated the effects of chronic, low-dose narrowband UVB irradiation on substrate utilization, circulating metabolites, and thermogenesis of brown adipose tissue (BAT) in …
jp
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Accès ouvert
2025
article
OpenAlex
Kazuaki Mawatari, Yasuko Kadomura-Ishikawa, Takahiro Emoto, Yushi Onoda et autres
Irradiation with ultraviolet light-emitting diodes (UV-LEDs) represents a promising method for viral inactivation, but a detailed understanding of the wavelength-dependent action spectra remains limited, particularly across different viral components. In this study, we established standardized UV action spectra for infectivity reduction in …
jp, us
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Accès ouvert
2025
article
OpenAlex
Kai Ishida, Miharu Nagahashi, Yushi Onoda, Toshihiko Aizawa et autres
Ultraviolet-light emitting diodes (UV-LEDs) have garnered attention for their efficient bacterial inactivation. However, in previous studies, it has been difficult to strictly compare the bacterial inactivation effect of UV irradiation among wavelengths differing by a few nanometers because detailed UV irradiation conditions …
jp
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Accès ouvert
2025
article
OpenAlex
Tran Quang Duc, Takashi Uebanso, Kazuaki Mawatari, Akira Takahashi
The gut microbiota plays a vital role in human physiology and nutrient metabolism. However, its capacity to synthesize essential amino acids (EAAs) as a nutrient source remains insufficiently characterized, with genomic evidence suggesting this potential but lacking direct in vitro validation. To …
jp
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Accès ouvert
2025
article
OpenAlex
Koichi Shinoda, Kazuaki Mawatari, Thi Kim Ngan Bui, Yasuko Kadomura-Ishikawa et autres
Far-UVC has emerged as a promising alternative for ultraviolet germicidal irradiation (UVGI). We developed a novel far-UVC light source using Luminous Array Film (LAFi), which excites phosphors by plasma discharge in a neon–xenon gas mixture within a glass tube. An optimal phosphor …
jp
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Accès ouvert
2025
article
OpenAlex
Michiyo Yamashita, Mutsumi Aihara, Yushi Onoda, Shiho Fukushima et autres
Fungi are one of the main sources of microbial contamination in food and residential environments. There has been reported that fungi are more resistant to drugs than are viruses and bacteria, so efficient sterilization methods are still required. In this study, we …
jp
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Accès ouvert
2024
article
OpenAlex
Sho Hatayama, Takaaki Shimohata, Junko Kido, Aya Tentaku et autres
Campylobacter jejuni (C. jejuni) is a causative food poisoning bacterium, it mainly ingesting undercooked chicken meat. Additionally, cooking utensils treated with raw chicken meat contaminated with C. jejuni and can induce the cross-contamination of food. Therefore, disinfection of kitchen equipment is a …
jp, gb
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Accès ouvert
2024
article
OpenAlex
Yushi Onoda, Miharu Nagahashi, Michiyo Yamashita, Shiho Fukushima et autres
Fungal contamination poses a serious threat to public health and food safety because molds can grow under stressful conditions through melanin accumulation. Although ultraviolet (UV) irradiation is popular for inhibiting microorganisms, its effectiveness is limited by our insufficient knowledge about UV tolerance …
jp, us
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Accès ouvert
2024
article
OpenAlex
Takao Nammo, Nobuaki Funahashi, Haruhide Udagawa, Junji Kozawa et autres
A lack of social relationships is increasingly recognized as a type 2 diabetes (T2D) risk. To investigate the underlying mechanism, we used male KK mice, an inbred strain with spontaneous diabetes. Given the association between living alone and T2D risk in humans, …
jp, us
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Accès ouvert
2024
article
OpenAlex
Kai Ishida, Yushi Onoda, Yasuko Kadomura-Ishikawa, Miharu Nagahashi et autres
Ultraviolet (UV) light is an effective disinfection method. In particular, UV light-emitting diodes (UV-LEDs) are expected to have many applications as light sources owing to their compact form factor and wide range of choices of wavelengths. However, the UV sensitivity of microorganisms …
jp
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